
Neuropsychopharmacology (NPP) is an official peer-reviewed publication of @ACNPorg. We report discoveries and promote training & outreach initiatives.
Nashville, TN
Joined February 2017
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This Hot Topics article highlights how interactions among multiple cell types may shape the onset and progression of schizophrenia
nature.com/articles/s41386-0…
How does THC affect emotion regulation in PTSD?
THC produced dose-related reductions in prefrontal engagement during negative emotion reappraisal, suggesting a role for cannabinoids in re-engaging efficient emotion regulation strategies in PTSD
nature.com/articles/s41386-0…
A rank-specific prefrontal-accumbens circuit links alcohol exposure to competitive social behavior
nature.com/articles/s41386-0… "
Ketamine reduced pain and pain-related brain activity while increasing dissociation, but these effects did not co-vary behaviorally or neurally, consistent with distinct correlates of its analgesic and dissociative properties
nature.com/articles/s41386-0…
In mice, fear conditioning triggers not only freezing, but also proximity-seeking toward a familiar partner. This social response requires an amygdala–hippocampus pathway & oxytocin signaling, and operates independently of freezing via a distinct circuit
nature.com/articles/s41386-0…
Welcome back to another rundown of what's new #ThisWeekInNPP
This week we're covering the latest on alcohol, kappa opioid receptors, norepinephrine, MDMA, and psilocybin 🍺💊🍄
#TWiNPP
#TWiNPP
A living systematic review and meta-analysis supports MDMA-assisted therapy as a promising treatment for PTSD / @singletonion @sattertt
nature.com/articles/s41386-0…
#TWiNPP
Results from Floris & Jefferson et al. suggests that phosphodiesterase-9 inhibition may improve the tolerability of psilocybin while maintaining its therapeutic potential
nature.com/articles/s41386-0…
This Hot Topics article proposes spousal relationships as an understudied determinant of cognitive aging and resilience
nature.com/articles/s41386-0…
Cannabis use may provide cognitive benefits for people with bipolar disorder
nature.com/articles/s41386-0…
In a large-scale study of MRI scans, a neuroanatomical signature of depression was identified across multiple cohorts
nature.com/articles/s41386-0…
Findings from animal models suggest that adolescent antipsychotic treatment may produce lasting alterations in cortical circuity that could influence adult brain function
nature.com/articles/s41386-0…
Neuropsychopharmacology retweeted
Symposia Submissions for #EBPS2027 in Cork, Ireland are now open. We have a great lineup of keynote presentations and are seeking symposia proposals covering a range of behavioural pharmacology topics.
More information on our website
ebps.org/events/ebps-2027-bi…
Buckle up, because we're back with another installment of #ThisWeekInNPP 💺
This week, we highlight emerging insights regarding obesity and metabolic disorders, as well as extinction and generalization in fear-related disorders
#TWiNPP
#TWiNPP
Here, Lee et al. identify ICER as a molecular regulator of inhibitory plasticity in amygdala fear engram neurons, linking weakened PV-mediated inhibition via Gabra1 suppression to maladaptive fear generalization
nature.com/articles/s41386-0…
#TWiNPP
From Hammerman et al., hippocampal dopamine-dependent memory updating supports more effective fear extinction, providing potential implications for PTSD and fear-related disorders
nature.com/articles/s41386-0…



