@DelgoffeLab

Cancer Immunometabolism - Professor - Director: Tumor Microenvironment Center - @PittTweet @UPMCHillmanCC - CoFounder:Novasenta - EiC:Immunology - views my own

 Pittsburgh, PA
delgoffe-lab.com
Joined June 2017
  • Tweets2.3K
  • Following395
  • Followers7.2K
263Media
Dearest gentle reader, we are delighted to announce a new story from our lab published in @Nature describing how a meal's systemic metabolic changes are interpreted by your immune system to enhance adaptive immunity. A thread 1/ nature.com/articles/s41586-0…
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Acyn
@AcynOct 25
TRUMP on HIGH GAS PRICES: We’re making money like we’ve never made before. They’ll say: President Trump is bragging about all the money they're making while people are suffering at the pump. I don’t give a damn. We’re making a freaking fortune.
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Excited to have played a role in this study of how diet and lifestyle can play roles in toxicities from checkpoint blockers. A tour de force from the Overacre group; check it out!
Overacre Lab@OveracreLabOct 22
Very excited to share our latest paper, out today in Cell, led by @ItzDipyaman! This project started out with a curiosity as to how and why irAEs happen. Even more peculiar is that WT mice never develop irAEs…and why was that? cell.com/cell/fulltext/S0092…

Lifestyle-induced regulatory T cell fragility primes adverse events after immune checkpoint blockade

Dietary and microbial alterations increase susceptibility to irAEs by promoting IFN-γ-driven Treg fragility and cytotoxic tissue-resident T cell responses. Treg-specific disruption of IFN-γ signaling...

cell.com
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Leaders of the House and Senate appropriations committees warned the White House not to impose new controls on how the NIH awards research grants. Political officials are weighing the creation of a commission to review awards. wapo.st/4AwjmCy

Congressional leaders warn White House against adding controls over NIH grants

Political officials are weighing the creation of a commission to review awards by the National Institutes of Health, The Post reported.

washingtonpost.com
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Someone with the right idea!
Jason Ukman@JasonUkmanSep 21
NEW: Reed Jobs, a prominent biotech investor (and son of another Jobs you may have heard of), calls for a doubling of the NIH budget to $100 billion. Via @statnews statnews.com/2026/09/21/nih-…

The NIH budget should be $100 billion per year

“We should be strengthening our investment in the NIH, not dismantling it,” writes Reed Jobs.

statnews.com
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Thanks for saying what we are all thinking.
Maggie Lovitt
@maggieofthetownSep 21
We live in hell
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We're sorry Western Michigan. NCAA Football Oversight Committee said if instant replay protocals at Michigan had been correctly followed, game's outcome would have been different. But they can't overturn the result. Remains a Michigan victory on3.com/news/fbs-oversight-c…

FBS Oversight Committee says protocols were not followed at end of WMU-Michigan, outcomes cannot be...

The FBS Oversight Committee has weighed in on the controversy surrounding the Western Michigan (WMU) vs. Michigan game.

on3.com
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Luke Sampe
@LukeSampeSep 13
Vikings 12th man today.
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The College Football Playoff has ruled to OVERRIDE Michigan’s win over WMU. The committee announces the game will officially be scored 12-7 in favor of Western Michigan. Historic 🤯
Readers added context they thought people might want to know
This post from the known parody account @BallsackSports falsely claims the CFP overrode the result. No such ruling was made; Michigan's official 13-12 win stands. footballscoop.com/2026/09/08/nca… espn.com/college-footba… apnews.com/article/michig…
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CFB Kings
@CFBKingsSep 8
BREAKING: Western Michigan has submitted formal appeals to the NCAA FBS Oversight Committee and the College Football Playoff to be recognized as the winner of their game vs. Michigan. The MAC commissioner states, “After further study and investigation, it is now evident that replay protocol was not properly followed in determining whether time remained.”
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Adding 1 second to the clock
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Lyle@WalkWithLyleSep 6
Recap of the Western Michigan-Michigan game
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As a proud alumnus of @WesternMichU, I have no words. Which is rare for me.
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Jason Shepherd@JasonSynapticSep 4
As director of a PhD program in the US...every week we have to deal with complete stupidity from our own government about international students. Serves no purpose other than chaos.
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Basil🧡
@LinkofSunshineSep 2
they already did
vo
@vanillaopinionsSep 2
they should make an affordable version of chicago
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Waggoner Lab@LabWaggonerAug 31
Review: Decoding T cell exhaustion in the tumour microenvironment nature.com/articles/s12276-0…
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K Holley@holleysweetlifeAug 28
Replying to @whole_isticway @factpostnews
What this graph doesn’t show is that many of the previous years’ recalls were voluntary after safety inspections found something during routine testing. This year’s recalls are happening bc people are getting sick and THEN the investigation and recall happens. That’s different.
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Tech entrepreneurs pivoting into biotech because it seems fun to cure all diseases when they realize that biology is hard
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View the complete details on this recall at: fda.gov/safety/recalls-marke….
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