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Discover the latest research from Vinny Augustine @UCSanDiego and an outstanding international community at #CPSNeuroImmune27 in New York.
Abstract deadline: April 30, 2027
hubs.li/Q04DyPVC0
Immunity retweeted
1) 📢 New study out in @ImmunityCP : We show that tumor-to-cDC1 reprogramming induces tertiary lymphoid structures (TLSs) across cancers. Read it here:sciencedirect.com/science/ar…. A thread 🧵
#TLS #reprogramming #immunotherapy
Graphical abstract by Avesta Rastan.
Online now: Tumor-to-dendritic cell reprogramming induces immunogenic lymphoid structures across cancers dlvr.it/TWBfLG
Online now: Mitochondrial DNA abundance is a determinant of immunogenic cell death in cancer dlvr.it/TW6zH0
Online now: Growth factor VEGF-B sustains intestinal Tfh cell stemness to restrict Taurinivorans outgrowth and microbiota-driven obesity dlvr.it/TW6F82
Immunity retweeted
Efficacy of PD-L1×4-1BB antibodies relies on PD-L1+ cDC1, which integrate antigen cross-presentation, IL-12, & 4-1BB costimulation to promote efficacious T cell-mediated antitumor immunity
cell.com/immunity/abstract/S… @ImmunityCP @DrIgMelero
@ClinicaNavarra @Teijeira_ITLive 🇪🇸
Immunity retweeted
PD-L1 on B cell zone reticular cells, including follicular dendritic cells, promotes humoral immunity by restraining a subset of Tfh that promotes Tfr development @ImmunityCP @eakamagarren @BostonChildrens
cell.com/immunity/abstract/S…
Online now: T cell cross-priming by PD-L1+ type 1 conventional dendritic cells mediates the antitumor efficacy of a PD-L1×4-1BB bispecific antibody dlvr.it/TW5dCV
Online now: PD-L1 expression in germinal centers promotes humoral immunity by restricting T follicular regulatory cell differentiation dlvr.it/TW5W2b
Hear from keynotes Ardem Patapoutian @ardemp @scrippsresearch & Gloria Choi @MIT at #CPSNeuroImmune27 in New York @NYAMNYC and share your own research with the neuroimmunology community.
Abstract deadline: April 30, 2027
hubs.li/Q04CtNzQ0
Online now: A microbiome-reactive TMIGD2hi Th17 subset is spatially enriched at the intestinal epithelium and expanded in inflammatory bowel disease dlvr.it/TW48GH
Online now: NF-κB phosphorylation controls enhancer selection to shape the inflammatory gene program dlvr.it/TW2L64
Immunity retweeted
Why Some People Age Like Fine Wine
CD8 cells in the immune system appear to reflect how healthy one's old age will likely be and could lead to a diagnostic test of aging. thedoctorwillseeyounow.com/c… #Aging #agingwell #immunity @ImmunityCP #immunehealth #inflammation #Granzymes #CD8
Immunity retweeted
Why does it take repeated exposures to become allergic, and why does one allergy lead to others? I talked with Claudia Hammond on BBC Health Check about our new @ImmunityCP paper: sensory neurons in mice remember allergen exposure. 🎧 podcasts.apple.com/us/podcas…
Immunity retweeted
Embracing macrophage complexity for research and translation. cell.com/immunity/fulltext/S… @ImmunityCP
Immunity retweeted
Spotlighting the macrophage cells in our blood and tissue, their role in diseases, and targeted interventions
cell.com/immunity/fulltext/S… @ImmunityCP
Immunity retweeted
What comes after M1/M2? In our Perspective with @FGinhoux in @ImmunityCP we explore how single-cell technologies and AI can decode the gene programs macrophages use across tissues & microenvironments, and how this modular view could transform immunotherapy
cell.com/immunity/abstract/S…
Immunity retweeted
This @ImmunityCP study found that #microglia exhibited acute and progressive morphological responses that preceded but paralleled ethanol-induced sedation.
📖 bit.ly/47jOSWW
First authors Evi Paouri and Sarah Stanko show that genetic deletion of microglial Myd88 protect against ethanol-induced microglial reactivity, neuronal damage and dysfunction, intoxication, and motor impairments by preventing #ECM disruption.

























