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Cutting-edge research in immunology from around the world. This account is no longer monitored, and content is automated. Join us on LinkedIn!

Cambridge, MA, USA
Joined May 2011
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Discover the latest research from Vinny Augustine @UCSanDiego and an outstanding international community at #CPSNeuroImmune27 in New York. Abstract deadline: April 30, 2027 hubs.li/Q04DyPVC0
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1) 📢 New study out in @ImmunityCP : We show that tumor-to-cDC1 reprogramming induces tertiary lymphoid structures (TLSs) across cancers. Read it here:sciencedirect.com/science/ar…. A thread 🧵 #TLS #reprogramming #immunotherapy Graphical abstract by Avesta Rastan.
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Online now: Tumor-to-dendritic cell reprogramming induces immunogenic lymphoid structures across cancers dlvr.​it/TWBfLG
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Online now: Mitochondrial DNA abundance is a determinant of immunogenic cell death in cancer dlvr.​it/TW6zH0
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Online now: Growth factor VEGF-B sustains intestinal Tfh cell stemness to restrict Taurinivorans outgrowth and microbiota-driven obesity dlvr.​it/TW6F82
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Efficacy of PD-L1×4-1BB antibodies relies on PD-L1+ cDC1, which integrate antigen cross-presentation, IL-12, & 4-1BB costimulation to promote efficacious T cell-mediated antitumor immunity cell.com/immunity/abstract/S… @ImmunityCP @DrIgMelero @ClinicaNavarra @Teijeira_ITLive 🇪🇸
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PD-L1 on B cell zone reticular cells, including follicular dendritic cells, promotes humoral immunity by restraining a subset of Tfh that promotes Tfr development @ImmunityCP @eakamagarren @BostonChildrens cell.com/immunity/abstract/S…
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Online now: T cell cross-priming by PD-L1+ type 1 conventional dendritic cells mediates the antitumor efficacy of a PD-L1×4-1BB bispecific antibody dlvr.​it/TW5dCV
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Online now: PD-L1 expression in germinal centers promotes humoral immunity by restricting T follicular regulatory cell differentiation dlvr.​it/TW5W2b
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Hear from keynotes Ardem Patapoutian @ardemp @scrippsresearch & Gloria Choi @MIT at #CPSNeuroImmune27 in New York @NYAMNYC and share your own research with the neuroimmunology community. Abstract deadline: April 30, 2027 hubs.li/Q04CtNzQ0
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Online now: A microbiome-reactive TMIGD2hi Th17 subset is spatially enriched at the intestinal epithelium and expanded in inflammatory bowel disease dlvr.​it/TW48GH
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Online now: Human brain cellular xenografts in neuroimmunology and beyond dlvr.​it/TW4233
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Online now: NF-κB phosphorylation controls enhancer selection to shape the inflammatory gene program dlvr.​it/TW2L64
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Why Some People Age Like Fine Wine CD8 cells in the immune system appear to reflect how healthy one's old age will likely be and could lead to a diagnostic test of aging. thedoctorwillseeyounow.com/c… #Aging #agingwell #immunity @ImmunityCP #immunehealth #inflammation #Granzymes #CD8
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Why does it take repeated exposures to become allergic, and why does one allergy lead to others? I talked with Claudia Hammond on BBC Health Check about our new @ImmunityCP paper: sensory neurons in mice remember allergen exposure. 🎧 podcasts.apple.com/us/podcas…
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Immunity retweeted
Spotlighting the macrophage cells in our blood and tissue, their role in diseases, and targeted interventions cell.com/immunity/fulltext/S… @ImmunityCP
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Immunity retweeted
What comes after M1/M2? In our Perspective with @FGinhoux in @ImmunityCP we explore how single-cell technologies and AI can decode the gene programs macrophages use across tissues & microenvironments, and how this modular view could transform immunotherapy cell.com/immunity/abstract/S…
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This @ImmunityCP study found that #microglia exhibited acute and progressive morphological responses that preceded but paralleled ethanol-induced sedation. 📖 bit.ly/47jOSWW First authors Evi Paouri and Sarah Stanko show that genetic deletion of microglial Myd88 protect against ethanol-induced microglial reactivity, neuronal damage and dysfunction, intoxication, and motor impairments by preventing #ECM disruption.
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Online now: Embracing macrophage complexity for research and translation dlvr.​it/TVxZsp
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