A 3-part clinical anthology on breast cancer screening is now live. Explore risk-stratified models, tailored dense breast strategies, and evidence-based next steps after abnormal findings. mdsc.pe/4rSWCsm

In managing high-risk IgA nephropathy (IgAN), what is your biggest clinical priority when evaluating emerging complement inhibitors?

More men are using testosterone than ever before. Prescriptions for testosterone replacement therapy (TRT) increased by 27% from 2018 to 2024, including a 58% increase among men aged between 35 and 44 years, a demographic in which a physician wouldn't expect to see symptoms associated with low testosterone. The American Urological Association estimates that perhaps a third of TRT recipients don't meet diagnostic criteria, and as many as 1 in 4 receive prescriptions without any measurement of their testosterone levels. Experts point to the influence of social media and the proliferation of online clinics marketing testosterone as a lifestyle product. Research also suggests that many are reluctant to disclose their steroid use to clinicians, often because they anticipate judgment or lack confidence in the doctor's ability to provide meaningful information or advice. So how can you begin the conversation with your patients about testosterone? Tap the link to read the story. mdsc.pe/3U9xQI7

Personalize cardiovascular prevention by matching strategies to each patient’s risk profile, preferences, and clinical needs. Explore practical methods for tailoring prevention plans and supporting better long-term outcomes. 🔗 mdsc.pe/4AQ8M9p

Among adults with type 2 diabetes (T2D) and atrial fibrillation (AF) or atrial flutter, starting a GLP-1 receptor agonist (RA) was linked to a 21% lower 1-year risk of developing venous thromboembolism compared with starting a DPP-4 inhibitor. "GLP-1RA's favourable VTE [venous thromboembolism] profile among patients with AF/AFL [atrial flutter] and T2DM [T2D] suggests that GLP-1RAs may confer vascular benefits and could be considered when selecting glucose-lowering therapy in this high-risk population. Importantly, these findings do not alter the established role of OAC [oral anticoagulant] for the prevention of AF-related stroke and systemic embolism," the authors wrote. mdsc.pe/4z7EH3Y

VDPHL01, an oral, extended-release formulation of minoxidil, successfully regrew hair in men with androgenetic alopecia over 6 months in a phase 3 trial, according to the product’s developer. In the phase 3 study of 536 men with mild-to-moderate male pattern hair loss, patients were randomly assigned to receive VDPHL01 8.5 mg once daily, VDPHL01 8.5 mg twice daily, or placebo. Phase 2 data were released last year, as reported by Medscape Medical News. mdsc.pe/4yA6d9a

As Manitoba adopts permanent daylight saving time, clinicians must consider health outcomes. mdsc.pe/4iflTZe

The buzz about retatrutide and the rapid uptake in GLP-1 use for weight loss could drown out the message that obesity is a complex, multifactorial disease requiring individualized, long-term management and instead shift focus to a public discourse on which drug helps people lose the most weight the fastest. Patients may be drawn to rapid weight loss, but treatment goals should be gradual and tailored to each patient’s health needs, personal circumstances, and preferences, with an emphasis on sustainable, long-term health improvements, according to the American Diabetes Association. mdsc.pe/4jBadCC

⚖️ Can we improve stroke prevention while minimizing bleeding risk? Explore emerging anticoagulation approaches, including FXI/XIa inhibitors, and the latest evidence shaping the future of patient care. 🔬 #AAFPFMX xitter.cf/i/broadcasts/1DxLdZleY…

⚖️ Can we improve stroke prevention while minimizing bleeding risk? Explore emerging anticoagulation approaches, including FXI/XIa inhibitors, and the latest evidence shaping the future of patient care. 🔬 #AAFPFMX xitter.cf/i/broadcasts/1DxLdZleY…

In the week ending October 10, 5% of flu tests run by clinical labs came back positive, up from 3.9% the week before, according to the CDC’s first weekly flu report of the season. The West Coast is seeing the most activity, and nearly all of it is H1N1, which made up 96% of the influenza A viruses the public health labs subtyped. The CDC said activity is higher than usual for this time of the year, though still within normal range of seasonal variation. The basic clinical approach hasn’t changed in view of an early flu season, two experts told Medscape Medical News. But the early start may have caught many patients before their flu shot, putting more weight on testing and antiviral decisions that are rarely clear-cut. mdsc.pe/488xCUR

What transformative science awaits at the upcoming #ESH Meeting in Basel? Our expert panelists give an exclusive preview of the key themes, scientific breakthroughs, and innovations in hypertension. Watch the full discussion ➡️ mdsc.pe/4jshO6m #MedEd #Hypertension

If you find it hard to keep patients exercising, you’re not alone: even in carefully designed studies, attrition ranges from 25% to 50%, and those who finish adhere only about 66% of the time. Motivational messages usually focus on the benefits of starting, such as a stronger heart, better balance, lower blood pressure, and improved brain health. But what happens when you stop? That may or may not motivate someone, but understanding the cellular effects of quitting could help patients recovering from injury or surgery, undergoing cancer treatment, or on bed rest, as well as people taking a break after a goal like a marathon. Tap the link to read more: mdsc.pe/3U9RqE6

Heading to #ESMO26? Hear from Prof. Susana Banerjee about an upcoming satellite symposium on novel targeted agents in platinum-resistant ovarian cancer. Visit booth #8072 to learn more. #OvarianCancer #Oncology

Could shorter, pulsed treatment strategies change how we manage mild-to-moderate NTM-MAC lung disease? Dr. Flume and Dr. Winthrop discuss shifting patient care goals and testing new treatment approaches. Watch the full discussion ➡️ mdsc.pe/4iidLHI #Pulmonology #CME

Updates to an FDA-approved colorectal cancer blood test increased the detection of advanced precancerous lesions, a new study showed. “The updated test has improved performance, better detection of advanced precancerous lesions, resulting in larger projected reductions in CRC incidence and mortality at the population level,” said first author Aasma Shaukat, MD, MPH, of the NYU Grossman School of Medicine in New York City. Although colonoscopy and stool-based testing continue to be recommended as first-line screening in American Cancer Society guidelines, “for patients who are unwilling or just will not proceed with screening, we can consider offering them a blood test,” said Shaukat, who presented the findings at the American College of Gastroenterology 2026 Annual Scientific Meeting. Read more at the link: mdsc.pe/3U6r4CY

Up to 80% of systemic sclerosis patients develop pulmonary or cardiac involvement, yet care often remains fragmented across isolated specialties. Managing a complex, multi-system autoimmune condition requires more than independent consultations—it demands coordinated care pathways between rheumatology, pulmonology, cardiology, and dermatology. When care is siloed, organ involvement progresses undetected. Establishing strong referral pathways to designated Scleroderma Research & Treatment Centers is critical for long-term patient outcomes. That’s why Medscape supports the National Scleroderma Foundation Rocky Mountain Chapter and their efforts to champion integrated, multi-disciplinary care models. 🎥 Watch the full "Rare, but Resilient" discussion between Dr. Tracy Frech, She Shutes (Patient Advocate), and Medscape Education. Link in the comments. #FoodFight2026 #SclerodermaAwareness #RareDisease

Starting in 1 HOUR ➡️ mdsc.pe/3VAHGTM Ready to level up your T2D care? Join Dr. Anderson, Davida Kruger & Casey Wells LIVE to address real-world AID adoption! 🗓️ Today ⏰ 12:00pm ET #DiabetesCare #PrimaryCare #MedEd

Put imaging into action with real patient cases. Explore how imaging findings can inform diagnosis, clinical decision-making, and next steps in care. 🔗 mdsc.pe/4zcU0YI

A quality improvement project nearly quintupled the rate of children receiving evidence-based, shorter courses of antibiotics for pneumonia and sinus infections, cutting unnecessary drug exposure without increasing treatment failures, according to the researchers. Research increasingly shows shorter courses of antibiotics — 3-5 days for community-acquired pneumonia and 5-7 days for acute bacterial rhinosinusitis — are safe in children. But clinical adoption has lagged. mdsc.pe/4elyvwM