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トンヌラ

@37phoenix

へっぽこ内科医。なんちゃって感染症専門医。論文メモ。

 Japan
Joined November 2011
  • Tweets4.9K
  • Following160
  • Followers2.2K
23Media
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MSSA菌血症の重症患者に発症したセファゾリン関連凝固障害。Dakota Sicignano. Antimicrob Steward Healthc epidemiol. 2026;e320. cup.org/4zwbZKo
Cefazolin-associated coagulopathy in a critically Ill patient with MSSA bacteremia: a case report |...

Cefazolin-associated coagulopathy in a critically Ill patient with MSSA bacteremia: a case report |...

Cefazolin-associated coagulopathy in a critically Ill patient with MSSA bacteremia: a case report - Volume 6 Issue 1

cambridge.org
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成人の無症候性動脈硬化症の有病率. 頸動脈、大腿動脈の3D超音波や冠動脈CTで検査。18〜29歳の男8.7%、女性6.7%で動脈硬化を認めた。N Engl J Med. 2026;395:1818. PMID: 42670946.　pubmed.ncbi.nlm.nih.gov/4267…
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麻疹のreview. Ann Intern Med. PMID: 42970799. pubmed.ncbi.nlm.nih.gov/4297…
Measles - PubMed

Measles - PubMed

Measles is reemerging, with cases and outbreaks increasing across the United States and other countries where measles had previously been eliminated. Most U.S. physicians have no experience with...

pubmed.ncbi.nlm.nih.gov
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コウモリ媒介人獣共通感染症のreview. BMJ. 2026;395:e100560. PMID: 42875048. pubmed.ncbi.nlm.nih.gov/4287…
Bat-borne zoonoses: transmission, impact, prevention, and management - PubMed

Bat-borne zoonoses: transmission, impact, prevention, and management - PubMed

Climate change and biodiversity loss are global environmental crises driving emerging infectious diseases, including bat-borne pathogens of public health significance: Ebola, Marburg, Nipah, Hendra,...

pubmed.ncbi.nlm.nih.gov
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重症患者に対する重炭酸ナトリウム。ベイズSR&MA. 生存に対する利益はないが、腎代替療法は減らしそう。Intensive Care Med. PMID: 42970124. pubmed.ncbi.nlm.nih.gov/4297…
Sodium bicarbonate therapy for metabolic acidosis in critically ill patients: a Bayesian systematic...

Sodium bicarbonate therapy for metabolic acidosis in critically ill patients: a Bayesian systematic...

Current randomised evidence does not demonstrate a clear survival benefit from sodium bicarbonate therapy in critically ill adults with metabolic acidosis, but suggests a high probability of reducing...

pubmed.ncbi.nlm.nih.gov
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抗菌薬耐性淋菌の世界的疫学。JAC Antimicrob Resist. 2026;8:dlag245. PMID: 42979400. pubmed.ncbi.nlm.nih.gov/4297…
The global epidemiology of antibiotic-resistant Neisseria gonorrhoeae - PubMed

The global epidemiology of antibiotic-resistant Neisseria gonorrhoeae - PubMed

Antimicrobial-resistant Neisseria gonorrhoeae is an evolving global public health threat that increasingly limits treatment options for one of the world's most common sexually transmitted infections....

pubmed.ncbi.nlm.nih.gov
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黄色ブドウ球菌菌血症時のフォローアップ血液培養は過剰に行われている可能性がある。Iris D N Van Bommel. Open Forum Infect Dis. 2026:ofag685. academic.oup.com/ofid/articl…
Potentially excessive follow-up blood cultures in Staphylococcus aureus bacteremia: opportunities...

Potentially excessive follow-up blood cultures in Staphylococcus aureus bacteremia: opportunities...

Follow-up blood cultures in Staphylococcus aureus bacteremia frequently exceed recommendations, with 50.6% of follow-up sets not in line with guidelines. L

academic.oup.com
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HAP、VAPに対してイミペネム/シラスタチン/funobactamはイミペネム/知らスタチン/レレバクタムに対して14日死亡で非劣勢だった。Lancet Infect Dis. PMID: 42982070. pubmed.ncbi.nlm.nih.gov/4298…
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過敏性腸症候群と腸脳相関。Lancet. PMID; 42956794. pubmed.ncbi.nlm.nih.gov/4295…
Irritable bowel syndrome and related disorders of gut-brain interaction - PubMed

Irritable bowel syndrome and related disorders of gut-brain interaction - PubMed

Irritable bowel syndrome, chronic constipation, and functional diarrhoea are disorders of gut-brain interaction, the symptoms of which include abnormal stool consistency or frequency accompanied by...

pubmed.ncbi.nlm.nih.gov
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発熱性好中球減少症での直腸スワブで薬剤耐性菌や緑膿菌が陰性なら境域な経験的治療でもいいかもしれない。７日以内の直腸スワブの陰性的中率は緑膿菌　99.3％、薬剤耐性GN 98.1％。Int J Antimicrob Agents. PMID: 42966420. pubmed.ncbi.nlm.nih.gov/4296…
Challenging the Dogma: Can Rectal Colonization Status Guide Narrow-Spectrum Empiric Antibiotic...

Challenging the Dogma: Can Rectal Colonization Status Guide Narrow-Spectrum Empiric Antibiotic...

Among high-risk neutropenic patients, negative RS predicted very low risk of PA or MDR-GNB BSI, challenging routine empiric antipseudomonal coverage. However, the low BSI incidence in our cohort...

pubmed.ncbi.nlm.nih.gov
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標準的な口腔ケアバンドルに0.12％クロルヘキシジンを追加してもVAPの発生や28日死亡の低下にはつながらなかった。Crit Care. 2026;30:553. PMID: 42958418. pubmed.ncbi.nlm.nih.gov/4295…
Chlorhexidine within a standardized oral-care bundle for the prevention of ventilator-associated...

Chlorhexidine within a standardized oral-care bundle for the prevention of ventilator-associated...

Clinical Trials Regisrty- India (CTRI) identifier [CTRI/2024/02/062201], registered [01 February 2024].

pubmed.ncbi.nlm.nih.gov
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耳鳴りのガイドライン。Otolaryngol Head neck surg. 2026. PMID: 42861423. pubmed.ncbi.nlm.nih.gov/4286…
Clinical Practice Guideline: Tinnitus Update - PubMed

Clinical Practice Guideline: Tinnitus Update - PubMed

The Guideline Update Group made strong recommendations for the following Key Action Statements (KAS): Clinicians should distinguish patients with bothersome tinnitus from patients with non-bothersome...

pubmed.ncbi.nlm.nih.gov
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メタロβラクタマーゼとセリンβラクタマーゼ産生菌における死亡率の比較。明確な差はないが、エビデンスの確実性は極めて低い。SR&MA. Clin Microbiol Infect. 2026;32:1797. PMID: 42526797. pubmed.ncbi.nlm.nih.gov/4252…
Mortality in infections caused by metallo-β-lactamase- versus serine carbapenemase-producing...

Mortality in infections caused by metallo-β-lactamase- versus serine carbapenemase-producing...

Mortality comparisons between infections caused by MBL-producing and SBL-producing Enterobacterales did not show a clear difference, but certainty of evidence was very low. Carbapenemase class alone...

pubmed.ncbi.nlm.nih.gov
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ベリムマブ投与中の血清反応陰性梅毒. Clinical picture. Clin Microbiol Infect.2026;32:1823. PMID: 41724328.clinicalmicrobiologyandinfec…
A silent spirochete: Treponema pallidum in seronegative syphilis

A silent spirochete: Treponema pallidum in seronegative syphilis

A 38-year-old man with undifferentiated connective tissue disease presented with a 3-week history of pruritic, erythematous-to-brownish papules, macules, and patches on the face, trunk, extremities,...

clinicalmicrobiologyandinfection.org
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エルサレムでの麻疹で入院した患者の重症化予測因子。死亡率1.4％。91％はワクチン未接種。呼吸サポートや重度の脱水は入院やICU入室と関連。市中肺炎の合併は脂肪やECMOと関連。Clin Microbiol Infect. PMID: 42957093. pubmed.ncbi.nlm.nih.gov/4295…
Predictors of severe measles outcomes in hospitalized patients in Jerusalem, 2025 - PubMed

Predictors of severe measles outcomes in hospitalized patients in Jerusalem, 2025 - PubMed

Despite high access to medical care in this urban setting, measles caused substantial morbidity and mortality. Respiratory compromise, severe dehydration, and bacteremia identified patients at...

pubmed.ncbi.nlm.nih.gov
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市中肺炎に対する免疫調節療法。Narrative review. Luke Flower. Clin Microbiol infect.PMID: 42966612. pubmed.ncbi.nlm.nih.gov/4296…
Immunomodulatory therapies in bacterial community-acquired pneumonia: Current evidence and future...

Immunomodulatory therapies in bacterial community-acquired pneumonia: Current evidence and future...

Immunomodulation represents an important adjunctive therapeutic strategy in bacterial community-acquired pneumonia. Although progress has been made, particularly with corticosteroids, evidence...

pubmed.ncbi.nlm.nih.gov
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妊娠中のオロプーシェウイルスの感染は母体出血や胎児喪失のリスクが約3倍高くなった。胎児の中枢神経異常のリスクも増加。Lancet Infect Dis. PMID: 42896562.　pubmed.ncbi.nlm.nih.gov/4289…
Oropouche virus infection in pregnant women in Rio de Janeiro, Brazil: a prospective cohort study -...

Oropouche virus infection in pregnant women in Rio de Janeiro, Brazil: a prospective cohort study -...

For the Portuguese translation of the abstract see Supplementary Materials section.

pubmed.ncbi.nlm.nih.gov
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腸球菌菌血症、血管内感染に対する補助的βラクタム薬。Narrative review. Rachel A Foster . Ther Adv Infect Dis. journals.sagepub.com/doi/10.…
Adjunctive β-lactams in combination therapy for enterococcal bacteremia and endovascular infectio...

Adjunctive β-lactams in combination therapy for enterococcal bacteremia and endovascular infectio...

Enterococcal bacteremia and endovascular infections remain difficult to treat because of intrinsic antimicrobial tolerance, increasing resistance, and frequent ...

journals.sagepub.com
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小児の咳に対するはちみつと市販薬の比較。はちみつは睡眠の質がわずかに改善。咳の頻度や重症度には有意な差はなし。SR&MA. Eur J Pediatr. 2026;185:706. PMID: 42671586. pubmed.ncbi.nlm.nih.gov/4267…
Honey vs. pharmacological treatment for acute cough in children: a systematic review and meta-ana...

Honey vs. pharmacological treatment for acute cough in children: a systematic review and meta-ana...

• Post-hoc sensitivity analysis suggests that honey is more effective than pharmacological therapy across all symptom domains. • Honey should be actively promoted over antitussives medications in...

pubmed.ncbi.nlm.nih.gov
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カンジダ敗血症。誰に経験的治療を行うのか。Editorial. Crit Care Med. pMID: 42951887. pubmed.ncbi.nlm.nih.gov/4295…
Candida Septic Shock: If Every Hour Matters, Who Requires Empiric Therapy? - PubMed

Candida Septic Shock: If Every Hour Matters, Who Requires Empiric Therapy? - PubMed

Candida Septic Shock: If Every Hour Matters, Who Requires Empiric Therapy?

pubmed.ncbi.nlm.nih.gov
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