Sherif (@AS_Shabaan97) header
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Sherif

@AS_Shabaan97
Joined July 2020
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Finishing the second day of @CNS_Update with Dr. Jeremiah presenting our propensity-matched analysis comparing two-level ACDF vs. two-level CDA @MayoSpine @MayoNsgyRes @BenElderMD @anthony_mikula @FogelsonMD @NLakomkin @ZachAPennington
Image from Abdelrahman Hamouda, MD (@Abdelraahhmmann)
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Breast capsule #pathology #hemepath #breastpath #breastpathology
Image from Surgical Pathology Cases (@surgpathcases)
Image from Surgical Pathology Cases (@surgpathcases)
Image from Surgical Pathology Cases (@surgpathcases)
Image from Surgical Pathology Cases (@surgpathcases)
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🥇 THE FIRST PLACE 🥇 CONGRATULATIONS to @MizzouGI represented by our superstar @IslaamHMohamed winning THE FIRST PLACE in #Endotitans competition at the @AmCollegeGastro, just one day after their flabbergasting performance in the #GIJeopardy of the #ACG2026. Simultaneously, @EzzeldienIbrahi, who happens to be THE SINGLE BEST trainee I have ever worked with, was conquering the medical residents frontline with three presidential awards. This is what happens when interest meets discipline.
Image from Ash Almomani, MD (@AlmomaniMD)
Image from Ash Almomani, MD (@AlmomaniMD)
Image from Ash Almomani, MD (@AlmomaniMD)
Image from Ash Almomani, MD (@AlmomaniMD)
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What is the most likely diagnosis in this 10-year-old patient presenting with a congenital, solitary, yellow-orange, hairless, verrucous plaque on the scalp, with gradual thickening and papillomatous changes over time? Dr. Harinder Singh Sandhu
Image from C.Alberto Ortega (@albertoortegana)
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Excited to attend #ICCS2026 meeting this weekend in Miami! 🌴 This will be my first time attending a conference filled with hematopathologists! Poster#130: Flow Features of Acute Promyelocytic Leukemia: A Single Institution Quality Improvement Project @ICCS_Education
Image from mahsa Hajizadeh (@mahsahajizadeh)
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Hi #PathTwitter #PathX! I’m Peyman (pay‑mon), a US-based IMG applying to pathology this cycle. Excited to learn, connect, and grow in this field! Outside of work, I enjoy mountain biking 🚵🏼‍♂️, maintaining my bikes 🔧, and exploring new trails 🌄. #PathMatch2027 #Pathology
Image from Peyman Nejat, MD (@NejatPeyman)
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T-LGL leukemia. STAT3 p.Y640F +. Nice linear arrays of granular lymphocytes expressing CD8, TIA, and granzymeB. This is a nice @BloodJournal paper from @moricemdphd describing these findings (bit.ly/2GIJRvH). #hemepath @SocforHemepath @hematogones
Image from Michael Cascio, MD (@mjcascio)
Image from Michael Cascio, MD (@mjcascio)
Image from Michael Cascio, MD (@mjcascio)
Image from Michael Cascio, MD (@mjcascio)
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Middle-aged patient with bowel thickening. What’s your differential diagnosis? #hemepath #gipath
Image from Anna (Ania) B. Owczarczyk, MD PhD FASCP (@cebulka26)
Image from Anna (Ania) B. Owczarczyk, MD PhD FASCP (@cebulka26)
Image from Anna (Ania) B. Owczarczyk, MD PhD FASCP (@cebulka26)
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🔬 Granular cell tumor — high-yield pearls 📍 Clinical • Solitary, slow-growing, firm nodule • Head/neck common, especially tongue 👅 • Usually benign; malignant tumors are rare 🧫 Histology • Poorly circumscribed, infiltrative dermal/subcutaneous neoplasm • Large polygonal cells with abundant coarse eosinophilic granular cytoplasm • 🔥 Granules = numerous intracytoplasmic lysosomes/autophagolysosomes • PASD+, diastase-resistant granules (do you know anybody who does it?) • Cells dissect between collagen bundles and may involve nerves or skeletal muscle • Overlying pseudoepitheliomatous hyperplasia may mimic SCC ⚠️ 🧬 IHC • Conventional granular cell tumor = Schwannian, S100+/SOX10+ • Non-neural granular cell tumor = non-Schwannian, S100−/SOX10− #pathology #pathologists #pathTwitter #dermpath #dermatology #dermtwitter
Image from A. Sarah Erem (@CakePath)
Image from A. Sarah Erem (@CakePath)
Image from A. Sarah Erem (@CakePath)
Image from A. Sarah Erem (@CakePath)
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What causes the circumferential lucent spaces, sometimes called “windows”, between these cells? #Boardfodder
Image from Kathryn Lindsey (@PathologyKate)
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What’s the associated mutation? #BoardFodder
Image from Kathryn Lindsey (@PathologyKate)
Image from Kathryn Lindsey (@PathologyKate)
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Going into derm? This one’s for you! 👇 Skip it if you’re just derm-curious or a total beginner 🙂 🔬 Histo: Psoriasiform dermatitis (see below). 👀 Clinical: they really want eczema! 🧠 Beyond morphology: Can we really see everything on H&E? How many stains/ancillary are enough? There is always some sponge around the corner! 🧬 Cytokine ISH : NOS2 and IL17 were positive, supporting psoriasis and consistent with the histopathology. IL13 and IFNG were negative (attached table for expression patterns). 🔬 Histo is king—but not the whole kingdom anymore! #pathology #pathologists #pathTwitter #dermpath #dermatology #dermtwitter
Image from A. Sarah Erem (@CakePath)
Image from A. Sarah Erem (@CakePath)
Image from A. Sarah Erem (@CakePath)
Image from A. Sarah Erem (@CakePath)
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"Windows" and mitotic figures in benign mesothelial cells. Pleural effusion #cytology #CytoPath
Image from Hubert Lau (@HubertLauMD)
Image from Hubert Lau (@HubertLauMD)
Image from Hubert Lau (@HubertLauMD)
Image from Hubert Lau (@HubertLauMD)
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#Dermpath for #Residents - Recognizing some cutaneous cystic lesions #pathology #dermatology
- Steatocystoma: Thin squamous lining with sebaceous lobules in the cyst wall - Eccrine hidrocystoma: Unilocular dermal cyst lined by 1–2 layers of cuboidal cells - Apocrine hidrocystoma: Secretory apocrine lining with decapitation secretion - Bronchogenic cyst: Ciliated pseudostratified columnar lining; may show goblet cells or cartilage - Branchial cleft cyst: Squamous or respiratory lining with dense lymphoid tissue - Trichilemmal cyst: Abrupt trichilemmal keratinization without a granular layer

ALT - Steatocystoma: Thin squamous lining with sebaceous lobules in the cyst wall - Eccrine hidrocystoma: Unilocular dermal cyst lined by 1–2 layers of cuboidal cells - Apocrine hidrocystoma: Secretory apocrine lining with decapitation secretion - Bronchogenic cyst: Ciliated pseudostratified columnar lining; may show goblet cells or cartilage - Branchial cleft cyst: Squamous or respiratory lining with dense lymphoid tissue - Trichilemmal cyst: Abrupt trichilemmal keratinization without a granular layer

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IgG4-Related Sclerosing Mastitis 🔥🔬 A fibroinflammatory lesion characterized by dense lymphoplasmacytic infiltrates, storiform fibrosis, and increased IgG4-positive plasma cells. #PathX #PathTwitter #breastpath
Image from Raza Hoda, MD (@RazaHoda)
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Let’s review epithelial-myoepithelial lesions of the breast this week! 🦑 Collagenous Spherulosis 🔬 Well-circumscribed intraluminal spherules of basement membrane-like material surrounded by a dual epithelial-myoepithelial cell population. #PathX #PathTwitter #breastpath
Image from Raza Hoda, MD (@RazaHoda)
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Introducing our chief residents for the 2026-2027 academic year: Alex Luniewski and Kyle Carlson!
Image from UVA Pathology (@UVA_Pathology)
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Review sheet of these entities
Image from Meredith Herman, DO (@MeredithKHerman)
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Sherif retweeted
Ana Yuil (@ana_yuil) profile picture
Ana Yuil@ana_yuilApr 13
Nice example of adenoid cystic carcinoma. #cytologyrocks @TJLynnMD
Image from Ana Yuil (@ana_yuil)
Image from Ana Yuil (@ana_yuil)
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Second look! 🧐 Exaggerated intracanalicular growth pattern with leaf-like stromal fronds and hypercellular stroma. Which molecular alteration is characteristic? A) MED12 and TERT promoter mutations B) CTNNB1 (beta-catenin) mutation C) MYC amplification D) ETV6::NTRK3 fusion
Image from Charlie Herndon (@DrCycloPath)
Image from Charlie Herndon (@DrCycloPath)
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