Amit Deshwar retweeted
We are very excited about infrastructure for bio at Gradient; following our investments in polyphron.com (@thematthewosman), @gamowlabs, and @KernaLabs
Amit Deshwar retweeted
Just a periodic reminder:
RNA abundance ≠ transcription activity.
RNA abundance is also regulated by RNA degradation.
Amit Deshwar retweeted
we're recruiting a leader for our RNA process & production team @newlimit
this role will have an impact on all the products in our portfolio. you'll explore frontier chemistry, train and lead talented scientists, & shepherd products to the clinic.
DM me if you're interested!
Amit Deshwar retweeted
How will AI change the way we design genetic medicines?
Our co-founder Melissa J. Moore will be speaking at @endpts AI Day on Oct 14! Join her in exploring how next-generation foundation models will help scale custom medicines.
NYC + virtual
events.endpoints.news/aiday2…
Amit Deshwar retweeted
Hell f*cking yeah
SF we are soooo back
* LinkedIn networking will get banned for hellyeah rave series
So existed to bring the wildest and cutest crowd in SF for this banger
We are almost at cap - RSVP NOW ⬇️
SF Tech Week has enough rooms for networking.
On Oct 9, we are bringing the underground rave scene back to SF, introducing Out of Office-The Techno Sound, a one-of-a-kind multimedia immersive rave experience in the Bay Area.
Come rave with the cutest crowd in SF 🤫
* LinkedIn networking is strictly banned on the dance floor.
👇 RSVP link in thread
Amit Deshwar retweeted
We were pretty stoked to be the first investor in @KernaLabs They've been heads down building and have just published a detailed essay on the future of RNA medicine.
kernalabs.substack.com/p/mrn…
More to come.
Melissa built one of the first mRNA platforms at Moderna. Now she's writing about the future of mRNA in the era of AI
AI is rapidly expanding the supply of therapeutic ideas, but turning them into effective medicines is still hard.
In our new essay, our co-founder Melissa J. Moore explores how better mRNAs can unlock novel medicines, and why mRNA’s most important chapter is still ahead.
kernalabs.substack.com/p/mrn…
Amit Deshwar retweeted
Programmable medicine has the potential to solve some of our most pernicious chronic diseases. I’m profoundly excited by the future that @KernaLabs is bringing to life. With their work, I’m optimistic that many of the diseases that erode our quality of life can soon be eradicated.
AI is rapidly expanding the supply of therapeutic ideas, but turning them into effective medicines is still hard.
In our new essay, our co-founder Melissa J. Moore explores how better mRNAs can unlock novel medicines, and why mRNA’s most important chapter is still ahead.
kernalabs.substack.com/p/mrn…
Amit Deshwar retweeted
AI is rapidly expanding the supply of therapeutic ideas, but turning them into effective medicines is still hard.
In our new essay, our co-founder Melissa J. Moore explores how better mRNAs can unlock novel medicines, and why mRNA’s most important chapter is still ahead.
kernalabs.substack.com/p/mrn…
Amit Deshwar retweeted
.@newlimit is hosting a dinner in boston on sept 24 to connect with talented scientists & engineers
we promise an evening of surprising conversations, good food, & better company
let us know if you or a friend are interested in joining!
newlimit.notion.site/3cf10a8…
Amit Deshwar retweeted
Moderna just showed what mRNA can do beyond vaccines: its individualized cancer therapy, with Keytruda, succeeded in Ph3.
When LLMs began rapidly progressing 3y ago, we made a bet that AI models can outperform human-led design to create better mRNAs. 🧵1/4
Amit Deshwar retweeted
why we seeded @KernaLabs
Amit Deshwar retweeted
We started Kerna on the thesis that mRNA would become a widespread therapeutic modality beyond vaccines. Today, Moderna’s mRNA cancer therapy + Keytruda met its Ph3 endpoints.
We’re already building the foundation models and in vivo data engine for what comes next.
Amit Deshwar retweeted
while the rest of the world was hating on/sleeping on mRNA - we backed @KernaLabs , founded by the former CSO of Moderna along with @AmitDeshwar and @juliapeng__
Watch this space
BREAKING: Moderna stock, $MRNA, surges over +110% after announcing the first ever positive Phase 3 results for a personalized cancer vaccine.
Amit Deshwar retweeted
We're growing our investment team at Gradient! If you're looking to invest with the best in seed-stage AI, apply through the link below or ping me directly.
1/ This is one of the most unique times to invest at the seed stage: Capital is everywhere and software has been mostly commoditized.
Amit Deshwar retweeted
today is international ME/CFS awareness day.
millions of people are living with a disease most doctors still don’t understand.
just “your labs look normal” and “have you tried therapy?”
Amit Deshwar retweeted
Stumbled upon a weird LLM failure mode: if you ask Sonnet 4.6 to translate a DNA sequence to protein, the output includes Cyrillic characters ~50% of the time. The frequency is sensitive to spacing, which suggests a tokenization issue. Short writeup: erle.bio/blog/2026-03-22-fai…
