MPI for Multidisciplinary Sciences Fluorescent #probes for live-cell #nanoscopy: #STED, #MINFLUX and #confocal. We do the job, all of you judge if it is useful!
Göttingen, Germany
Joined September 2018
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Chromatin labeling and imaging retweeted
BREAKING NEWS
The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
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📢 We are hiring!
My lab is looking for a postdoctoral researcher. If you are excited about understanding cholesterol transport between the endoplasmic reticulum and mitochondria, membrane biology, lipid metabolism, or super-resolution imaging, please apply by June 30th!
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Illuminating microtubule architecture – Check out the associated News and Views by Rūta Gerasimaitė Gražvydas Lukinavičius
nature.com/articles/s41589-0…
Chromatin labeling and imaging retweeted
CenSpark is a dual-ligand fluorescent probe simultaneously binding inner and outer microtubule sites – a configuration unique to doublet and triplet microtubules, enabling selective live imaging of centrioles and cilia across species
nature.com/articles/s41589-0…
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Women lose >90% of their #eggs by their mid-30s, with persistent #DNADamage driving this loss. But why isn’t this damage repaired?
Our new work in @CurrentBiology, led by @ninadini_sharma, reveals the causes of high DNA damage in aged oocytes.🧬💥
bit.ly/48e35Ee (1/13)
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Cost of having DNA methylation: DNA replication by DNA polymerase epsilon is a source of C to T mutations in CpGs, especially methylated ones. This expands our understanding of one of the most widespread endogenous mutational mechanisms. nature.com/articles/s41588-0…
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A team led by Steffen Sahl & @Stefan_W_Hell @mpi_nat and @mpi_mr_hd has succeeded in measuring distances within biomolecules using the #MINFLUX microscopy method, down to 1 nanometer and with Ångström precision. Read more in our press release:
mpinat.mpg.de/4816514/pr_241…
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BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
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The highest scientific honor – the Oscar of science – is the @NobelPrize! 10 years ago, our director @Stefan_W_Hell received the #NobelPrize in #Chemistry. With the #STED (#STimulatedEmissionDepletion) microscopy & related processes, he revolutionized #lightmicroscopy. 🔬
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Thrilled to announce our review paper on STED microscopy is out! Grateful for the opportunity to contribute and learn so much throughout this journey 😎
STED microscopy enhances the spatial resolution by reducing the effective fluorescence emission volume, disrupting the linear relation between excitation and spontaneous emission probability.
Find out how in this weeks Primer: go.nature.com/4dD0PYX
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Our #STED primer is out, you can learn about tips and tricks and current challenges in STED imaging
STED microscopy enhances the spatial resolution by reducing the effective fluorescence emission volume, disrupting the linear relation between excitation and spontaneous emission probability.
Find out how in this weeks Primer: go.nature.com/4dD0PYX
Chromatin labeling and imaging retweeted
STED microscopy enhances the spatial resolution by reducing the effective fluorescence emission volume, disrupting the linear relation between excitation and spontaneous emission probability.
Find out how in this weeks Primer: go.nature.com/4dD0PYX
Chromatin labeling and imaging retweeted
Thanks to our amazing author panel for all their work: @IlariaTesta4, @scilifelab, @KTHUniversity, @AndImaging, @mpi_nat, @jonatanalvelid, @KTHuniversity, @scilifelab, @Leibniz_IPHT, @fran_bottanelli
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Jonas Bucevicius @J_Bucevicius @mpi_nat rocking the stage at @BOS_2024_Riga #BOS2024Riga.
Enhancing the #biocompatibility of #rhodamine fluorescent probes by positional isomerism.
Curiously enough even the screen turned fluorescent 🚦🤔
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Two 🔥 computational postdoc positions 🔥are available in our lab, funded by @ERC_Research ! embl.org/jobs/position/HH002… and embl.org/jobs/position/HH002…. Join us and unleash the power of these just-delivered beasts 👇And please repost to help us!
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Me again…my lab has another exciting position for a research assistant in computational biology: ki.varbi.com/en/what:job/job…
Please apply if you’re interested to work with large single-cell and in situ RNAseq datasets collected from experiments on the developing mouse brain!
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My lab is looking for a research assistant to work on barcoded viral tracing in the developing mouse brain: ki.varbi.com/what:job/jobID:…
Please apply if you’re interested to explore molecular mechanisms of neural circuit assembly in vivo!
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These days mark the #10Years anniversary of the #SiR-Actin and tubulin paper by @AndImaging. Will never forget the very first image we acquired in neurons with some beautiful actin rings 😀 here it is! nature.com/articles/nmeth.29…
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Inside every cell in your body, two metres of DNA is carefully folded into a structure smaller than the width of a human hair. This #DNADay, explore how every fold and twist in the origami of our DNA can affect our bodies and ultimately our health:
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Physicist Peter Higgs has passed away at the age of 94. The Higgs particle, often called the God particle, is named after him.
Higgs was awarded the 2013 physics prize for the theory of how particles acquire mass.
Watch our interview with him: youtu.be/0WduRCAlIig
ALT Official Nobel Prize portrait of Peter Higgs. He is wearing a dark suit and white shirt and a dark blue tie.