Angela, RPh, RChT💜 retweeted
God’s Good News
Hebrews 7:25
Jesus is able to save completely those who come to God through him, because he always lives to intercede for them.
Ephesians 2:8-9
It is by grace you have been saved, through faith, not by works, so that no one can boast.
Angela, RPh, RChT💜 retweeted
🧪 Ninhydrin = presence of AA (+violet)
🧪 Xanthoproteic = W, Y, F (+yellow)
🧪 Millon = Y (+rose/salmon)
🧪 Pauly's = Y, W, H (+red)
🧪 Hopkin-cole = W (+violet ring)
🧪 Sakaguchi = R (+red)
🧪 Na Nitroprusside = C (+red)
🧪 Biuret = peptide bond (+violet)
Angela, RPh, RChT💜 retweeted
💡random tests in ORGANIC CHEMISTRY💡
📌 baeyer's - alkenes
📌 belstein - alcohol
📌 Lucas - 2° and 3° alcohol
📌brady - aldehyde and ketones
📌 iodoform - methyl ketones
📌 hinsberg - amines
Angela, RPh, RChT💜 retweeted
TESTS‼️
—UNSATURATED compounds
• BROMINE
• BAEYER’S
• XANTHOPROTEIC
—HALOGENATED compounds
• BEILSTEIN
—OXYGEN containing compounds
• LUCAS
• FERRIC CHLORIDE
• JONES OXIDATION
• TOLLEN’S
• FEHLING’S
• BRADY’S
• IODOFORM
—NITROGEN containing compounds
• HINSBERG
Angela, RPh, RChT💜 retweeted
Tri Cats of Ms. Diaz
>SulfaDIAZine + TRImethoprim --> For Toxoplasmosis
Fancy ParaDox (PyriDox) ano meaning neto? MALAy ko (Malaria)
>PYRImethmine + SulfaDOXine (Fansidar [BN]) --> For Malaria
Sulfamethoxazole + Trimethoprim (Bactrim [BN], Co-Trimoxazole) --> For PCP
🛑 Biochemistry – Rate Limiting Steps (Must Know ⚡)
🔷️ Glycolysis → PFK-1
🔷️ Gluconeogenesis → Fructose-1,6-bisphosphatase
🔷️ Glycogenesis → Glycogen synthase
🔷️ Glycogenolysis → Glycogen phosphorylase
🔷️ TCA Cycle → Isocitrate dehydrogenase
🔷️ HMP Shunt → G6PD
🔷️ Fatty Acid Synthesis → Acetyl-CoA carboxylase (ACC)
🔷️ β-Oxidation → Carnitine acyltransferase I
🔷️ Cholesterol Synthesis → HMG-CoA reductase
🔷️ Urea Cycle → CPS-1
🔷️ Purine Synthesis → PRPP amidotransferase
🔷️ Pyrimidine Synthesis → CPS-2
💡 Exam Trick:
👉 “Synthesis = usually first committed step”
👉 “Breakdown = key control enzyme”
Angela, RPh, RChT💜 retweeted
COENZYMES: organic compound derived from vitamins
📍Biocytin (B7) - carboxylation
📍Coenzyme A (B5) - acetylation
📍NAD+/NADH (B3) - transfer of electrons
📍FAD+/FADH (B9) - transfer of electrons
📍Pyridoxal PO (B6) - transaminases
📍Thiamine pyrophosphate (B1) - decarboxylation
Angela, RPh, RChT💜 retweeted
📌 Phases of Metabolism
🌟 𝗛𝗢𝗥𝗚𝗚𝗚𝗔𝗦𝗠 🌟
Phase 1: Functionalization Rxn
𝗛ydrolysis
𝗢xidation
𝗥eduction
Phase 2: Conjugation Rxn
𝗚lucuronidation
𝗚lycine conjugation
𝗚lutathione conjugation
𝗔cetylation
𝗦ulfation
𝗠ethylation
Angela, RPh, RChT💜 retweeted
🤸♀️ REMEMBER
Neonates: 0-30 days (first 4 weeks)
Infants: 1mon-12mons
Toddlers: 1-3yrs
Preschoolers: 3-5yrs
Late Childhood: 6-12yrs
Adolescence: 13-17yrs
Angela, RPh, RChT💜 retweeted
USMLE step 1 nightmares:
- Pyrimidine metabolism
- Purine metabolism
- HMP shunt
- Glycolysis, Gluconeogenesis
- Glycogenolysis, Glycogenesis
- Fructose and Galactose metabolism
- Fatty acid metabolism
- Amino acid metabolism
- Ketone metabolism
- Krebs cycle
- Urea cycle
Angela, RPh, RChT💜 retweeted
M1:
📍inorg mk: drive.google.com/file/d/1lIn…
M2:
📍metab paths & tests compressed: drive.google.com/file/d/102g…
M3:
📍pharmcal formulas drive.google.com/file/d/1nz-…
M4:
📍drive.google.com/drive/folde…
M5: xori 😣
M6:
📍qc&qa mk drive.google.com/file/d/1EAL…
📍qc formulas drive.google.com/file/d/1NDV…
Angela, RPh, RChT💜 retweeted
Most Abundant Elements Of The Earth's Crust
Element - Approximate % By Weight
✅Oxygen - 46.6%
✅Silicon (Si) - 27.7%
✅Aluminium (Al) - 8.1%
✅Iron - 5.0%
✅Calcium (Ca) - 3.6%
✅Sodium (Na) - 2.8%
✅Potassium (K) - 2.6%
✅Magnesium (Mg) - 1.5%
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Angela, RPh, RChT💜 retweeted
Zinc (Zn²⁺):
Zinc is an essential trace element involved in immunity, wound healing, growth, and enzyme function. The body does not store zinc → regular intake is important.
⚙️ What Does Zinc Do?
-Immune function → supports T-cells & antibody production.
-Enzyme cofactor (over 300 enzymes).
-DNA synthesis & cell division.
-Wound healing & tissue repair.
-Taste & smell perception.
-Normal growth & sexual development.
📌 Clinical Uses of Zinc:
1️⃣ Zinc Deficiency Treatment:
-Common in malnutrition, chronic diarrheas, malabsorption, alcoholism.
-Deficiency signs:
-Poor wound healing
- Loss of taste/smell
- Alopecia
-Periorificial dermatitis
-Recurrent infections
2️⃣ Acute Diarrhea (Children):
-WHO recommends zinc to reduce duration & severity of diarrhea.
3️⃣ Wound & Burn Care:
-Enhances epithelial repair and healing.
4️⃣ Common Cold (Adjunct):
-May shorten symptom duration if started early (evidence mixed).
⚠️ Important Interactions & Tips:
•High zinc ↓ copper absorption → risk of copper deficiency.
•Separate zinc from iron, calcium, tetracyclines, quinolones (2–4 hours).
•Chronic high doses → GI upset, immune dysfunction.
🍽️ Dietary Sources:
-Oysters (highest)
-Red meat & poultry
-Nuts & seeds
-Whole grains
-Dairy
Angela, RPh, RChT💜 retweeted
Selenium (Se)✨:
Selenium is an essential trace element that plays a key role in antioxidant defense, thyroid hormone metabolism, and immune function.
⚙️ What Does Selenium Do?
•Antioxidant activity → part of glutathione peroxidase.
•Thyroid hormone metabolism → converts T4 → T3.
•Immune function → supports T-cell activity.
•Protection against oxidative stress.
•Cardiovascular health.
📌Clinical Uses of Selenium:
1️⃣ Selenium Deficiency Treatment
Seen in:
•Long-term parenteral nutrition
•Malabsorption syndromes
•Chronic diarrhea
•Severe malnutrition
Deficiency manifestations:
•Keshan disease(dilated cardiomyopathy).
•Muscle weakness.
•Recurrent infections.
•Cognitive changes.
2️⃣ Thyroid Support:
•Used in Hashimoto thyroiditis.
•Reduces thyroid peroxidase antibodies (TPO-Ab).
⚠️ Selenium Toxicity (Selenosis):
•Garlic-like breath odor,
•Nausea, diarrhea.
•Hair loss.
•Brittle nails.
•Irritability, fatigue.
📌 Usually from excess supplementation, not diet.
🍽️ Dietary Sources:
•Brazil nuts (very high – caution).
•Seafood.
•Eggs .
•Whole grains .
•Meat & poultry.






























