Ankit Kalucha (@Ankitowledge) header
Ankit Kalucha (@Ankitowledge) profile picture

Easing oncology outcomes decision making

India
Joined December 2023
Photo by Ankit Kalucha (@Ankitowledge)Photo by Ankit Kalucha (@Ankitowledge)Photo by Ankit Kalucha (@Ankitowledge)Photo by Ankit Kalucha (@Ankitowledge)Photo by Ankit Kalucha (@Ankitowledge)Photo by Ankit Kalucha (@Ankitowledge)Photo by Ankit Kalucha (@Ankitowledge)Photo by Ankit Kalucha (@Ankitowledge)Photo by Ankit Kalucha (@Ankitowledge)Photo by Ankit Kalucha (@Ankitowledge)
AI Derived Emerging Targets at ESMO 2026 #oncology #CancerCare #esmo #HealthcareAI
🤖 Made with AI
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The other side of ASCO 2026. Used Gen AI to synthesize ASCO 2026 KOL negative commentary into a simple signal map.
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Ankit Kalucha retweeted
NEW ASCO Guidelines Assistant tool leverages Google Cloud Vertex AI platform & Gemini models, enabling oncology clinicians to quickly access evidence-based clinical guidelines.

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Immune cell effector-associated neurotoxicity syndrome (ICANS) is a less well understood entity related to cytokine disruption of BBB and comprising diverse neurological symptoms. ICANS was rare (<10%) and no ICANS 3 or more was observed. (pic from Sands Cancer 2024) 🧵12/15
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Do ΔORR and ΔDoR Predict PFS and OS Hazard Ratios Across Cancer RCTs? #CancerTrials #RCTs #MedicalAI
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Deep research cost evaluation of the recent Stage IV NSCLC With Driver Alterations: ASCO Living Guideline v2024.3 #nsclc #ASCO #lungcancer #Oncology
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SWOT by Deep Research. Potential SOC SERENA 6.
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Generative Reward Models Self-Taught Reasoning (STAR) in AI Training for cancer clinical trials
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Mixture-of-experts Concepts
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Biomarkers, Molecular Targets, and Methods of Detection for Precision Medicines in NSCLC (ESMO guideline)
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🫁 NCCN guideline updated 🫁 🫁 Part-1, NSCLC 🫁 🌟 Version 9.2024 — September 9, 2024 🌟 📌 Ver. 8 was updated on August 23, 2024, so went to ver. 9 in about 2 weeks, right in the middle of WCLC 2024.
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🫁 Lung Cancer - ICIs data 🫁 🌟 Summary of 5-year (long follow-up) data 🌟 NSCLC (NSQ & SQ) #Immunotherapy #Lungcancer #longfollowup #LCSM
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Ankit Kalucha retweeted
Seems like Ontologies are back - 20 years ago, ontologies were gaining traction. W3C OWL became a standard - 10 years ago it was a red flag. Don’t say the “o word” - Now w/ LLMs, we have the need to manage knowledge in a structured & governed manner What comes around, goes around
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🎯PFS-2 is a better surrogate for OS than PFS in advanced cancer trials 🔥 👉 PFS-2 has a stronger correlation with OS benefit (r = 0.70 vs r = 0.46) 🤔Should PFS-2 be the primary endpoint in future trials??? @ASCO @myESMO @eaonc @SWOG @EORTC @VPrasadMDMPH @VincentRK #PFS2 #OS #CancerResearch ascopubs.org/doi/10.1200/PO.…
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Summary of 5 new drugs/indications in GI malignancies that were @FDAOncology @US_FDA approved in 2023: - #Tucatinib - Mountaineer - #TAS102 + #Bevacizumab - Sunlight - #Pembro + Cis/Gem - KN966 - #Fruquintinib - FRESCO2 - #Pembro + Chemo - KN859 #OncTwitter #gism #crcsm
Summary of the 4 new drugs/indications that were approved for GI malignancies by @FDAOncology in 2022: - Nivo & Ipi/Nivo - Durvalumab - Futibatinib - Treme + Durva #GastricCancer #MedEd @OncoAlert @ASCO #GIOncology #CRCSM #MedTwitter #OncTwitter #Oncology #gism
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🎆🎯2023 FDA approvals. 👉🏼The FDA approved 55 novel therapeutics in 2023, the second highest count in the past 30 years 🙌🏼 👍🏼The FDA’s Center for Drug Evaluation and Research (CDER) approved 55 new drugs in 2023, as the small molecule and biologic pharmacopoeia continues to grow @tmprowell @FDAOncology @US_FDA @OncoAlert @NatRevDrugDisc @statnews nature.com/articles/d41573-0…
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