
Developmental Neurobiologist @UZH_Science | Microscopy Enthusiast | Science communication | Bluesky: @axonsalex.bsky.social Youtube: @AlexNeuroHealth
Axonal growth cone
Joined August 2020
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Can small extracellular vesicles guide growing axons?
Our new preprint provides evidence that small extracellular vesicle (sEV) secretion regulates axon guidance at a key ventral midline choice point during spinal cord development.
biorxiv.org/content/10.64898…
#neuroscience #EV
Wiring Both Sides of the Nervous System 🔬
#FluorescenceFriday #Neuroscience #DevelopmentalBiology #Microscopy #LifeSciences
This video shows axons crossing the midline of the developing spinal cord.
A Sticky Dance Between a Cell and a Neuron. #neuroscience #science #mysterious #HiddenWorld #cell #FluorescenceFriday
➡️A Schwann cell precursor interacting with sensory axons 🔬🧫
This is how actin shapes the neuronal growth cone 🔬
When a neuron grows, it doesn’t just extend blindly. It actively moves, explores its surroundings, and makes decisions along the way.
#Neuroscience
#ScienceCommunication
#Microscopy
#brain
#Science #LifeSciences #neuron
This Is What Drives Axon Growth. Axon growth is powered by the actin cytoskeleton at the growth cone.
Here, filamentous actin dynamics drive fast, directed axon extension in real time. #Fluorescencefriday #science #neuroscience
Thrilled to collaborate with @ZhixingChen2 Lab @PKU1898!
We tested new PK Mem dyes—gentle, photostable tools to label the plasma membrane in live neurons, making it easier to track growth cone motility & axonal transport. #liveimaging #neuroscience
tiny.cc/3qhp001
This time-lapse captures 17h of axonal growth from a chick dorsal root ganglion explant, seen through the actin cytoskeleton using live imaging. I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours!😉 #neuroscience
Time-lapse recording of floorplate cytonemes (green) interacting with axons (magenta). 1 image taken every second for 10 min (played at 30 fps). Cytonemes love interacting with axons! 💚#FluorescenceFriday
Replying to @JeffreyHaren @UZH_Science
It even looks like the growth cone on the left is doing a breakdance 🌊 to propel the particle to the other side! #FluorescenceFriday