Dr Denis Koltsov (@BREC_Solutions) header
Dr Denis Koltsov (@BREC_Solutions) profile picture

Physics PhD, Nanotechnologist, Entrepreneur, Director, Advisor, Standards expert, Speaker - let me tell you about new and old technologies that impact our lives

UK and Poland
Joined March 2010
Photo by Dr Denis Koltsov (@BREC_Solutions)Photo by Dr Denis Koltsov (@BREC_Solutions)Photo by Dr Denis Koltsov (@BREC_Solutions)Photo by Dr Denis Koltsov (@BREC_Solutions)Photo by Dr Denis Koltsov (@BREC_Solutions)Photo by Dr Denis Koltsov (@BREC_Solutions)Photo by Dr Denis Koltsov (@BREC_Solutions)Photo by Dr Denis Koltsov (@BREC_Solutions)Photo by Dr Denis Koltsov (@BREC_Solutions)Photo by Dr Denis Koltsov (@BREC_Solutions)
No words can describe the loss this civilisation suffered with the passing of Sir Patrick Stewart.
🤖 Made with AI
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Formation Bio $600M AI drug-development accelerator fund Formation Bio (AI-native pharma, previously valued ~$1.7–1.8B) launched a $600M fund to acquire and advance 10–15 Phase 1–2 drug programs over 3–5 years. It pairs dedicated capital with its AI platform and clinical operations in a hub-and-spoke NewCo structure, aiming to cut development costs 30–50% by addressing the post-discovery bottleneck. Source: axios.com/2026/10/29/formati… #AIDrugDiscovery #Biotech #Startups #VentureCapital #IntellectualProperty
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Nanobubbles advancing direct lithium extraction One World Lithium completed delivery of custom Moleaer industrial nanobubble generators to labs at UC Irvine and University of British Columbia. The equipment supports R&D on their patent-pending single-step Direct Lithium Carbonation Extraction (DLCE) process using CO₂ nanobubbles to produce lithium carbonate from brines, with a field pilot planned for early 2027. Source: mining.com/one-world-lithium… #Nanobubbles #Lithium #AdvancedMaterials #CriticalMinerals #Startups
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MIT modular nanoparticle platform for personalized cancer vaccines MIT engineers created a modular platform using modified M13 bacteriophage nanofibers that can be coated with controlled densities of cancer antigens. In mice, optimized versions prevented tumor development and generated stronger T-cell responses. The approach is designed to be patient-specific by swapping antigens. Source: news.mit.edu/2026/mit-engine… #Nanotechnology #CancerVaccines #AdvancedMaterials #Biotech #ScientificDiscovery
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Physical Intelligence (physical AI / robotics foundation models) Physical Intelligence is in talks to raise at least $1B at a ~$20B valuation (nearly double prior), led by existing backers Avenir and Lux Capital. Pre-revenue, it builds vision-language-action models that power robots across hardware for real-world tasks and recently opened an API beta for developer fine-tuning. Source: bloomberg.com/news/articles/… #PhysicalAI #Robotics #AIStartups #VentureCapital #FoundationModels
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A new £7.125 million UK funding opportunity has opened for digital advanced-materials innovation. Announced on 29 October by UK Research and Innovation, the programme focuses on Materials 4.0: connecting materials research with AI, automation, digital twins, advanced characterisation and interoperable data. ukri.org/opportunity/nmip-sa… Between three and eight collaborative projects are expected to receive funding, with project durations of up to 33 months. The opportunity is open to eligible UK research organisations, with industry participation encouraged. Expressions of interest close on 26 November 2026 at 16:00 GMT. Conclusion: Materials informatics and digital infrastructure are becoming central priorities in translating advanced materials into commercial products.
🤖 Made with AI
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Researchers have synthesised a new two-dimensional titanium-boride material using molten-salt chemistry. Published on 29 October in Advanced Materials, the work demonstrates the production of multilayer Ti₂B₂Clₓ, part of the emerging MBene family. advanced.onlinelibrary.wiley… The researchers selectively removed indium from Ti₂InB₂ using molten ZnCl₂ while introducing chlorine surface terminations. In-situ X-ray diffraction and theoretical calculations supported the proposed direct transformation mechanism. Preliminary electrochemical testing also indicated promising lithium-storage behaviour. Conclusion: The family of experimentally accessible two-dimensional materials continues to expand beyond graphene and MXenes. Further work is needed on material properties, production scale and industrial applications.
🤖 Made with AI
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Researchers have reported a solid-state lithium-metal pouch cell achieving 515 Wh/kg energy density. Published on 29 October in Advanced Materials, the study introduces a fluorinated polymer electrolyte containing poly(ionic liquid) components. advanced.onlinelibrary.wiley… The material creates improved lithium-ion transport pathways while stabilising the lithium-metal interface. At 30°C, ionic conductivity reached 0.38 mS/cm, with a lithium-ion transference number of 0.77. Experimental Li||NCM90 cells retained approximately 81% capacity after 600 cycles. Conclusion: Polymer-electrolyte engineering remains a promising route towards higher-energy solid-state batteries. Industrial lifetime, manufacturing yield and full-cell safety qualification still require validation.
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Researchers have demonstrated an individually addressable molecular spin qubit with an optical interface. Published on 28 October in Nature, the study uses a specially designed carbene molecule embedded in a compatible crystal. nature.com/articles/s41586-0… At 4.5 K, the system demonstrated approximately 2.2 ms spin coherence and 21 ms spin relaxation, together with stable optical behaviour. On the same day, NVision announced a partnership with HyperLight to explore integration of molecular qubits with photonic integrated circuits. Conclusion: Molecular chemistry could become a powerful tool for engineering quantum hardware, potentially complementing semiconductor-based qubit technologies. Manufacturing scalability and useful quantum-computing performance remain future objectives.
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Scientists have identified a previously undescribed class of extracellular vesicles associated with cancer-cell migration. Published on 28 October in Nature Cell Biology, the study describes motile vesicles, or MoVes, measuring approximately 2–5 micrometres. Unlike conventional small EVs, these structures form during retraction of the trailing edge of migrating cancer cells. nature.com/articles/s41556-0… They contain genomic DNA, mitochondria and other cellular components. Remarkably, their mitochondrial cargo can influence energy metabolism in recipient cells. Conclusion: EV biology extends beyond small exosomes. Different vesicle populations may carry fundamentally different biological information. The discovery also highlights the need for orthogonal particle-characterisation methods.
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IIT Ropar: Nanobubbles Improve Paracetamol Crystallization Yields Up to 65% Bulk nanobubbles (150–200 nm, generated from O₂/N₂/CO₂) accelerate nucleation, reduce crystal size, and raise yields in cooling/antisolvent crystallization of paracetamol without added hazardous chemicals. Demonstrates a cleaner, more efficient path for pharmaceutical manufacturing. researchmatters.in/news/nano… #Nanobubbles #Nanotechnology #Pharma #AdvancedMaterials #ScientificDiscovery
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OpenAI Reportedly Plans to Buy Google TPUs (Beyond Nvidia) Reports indicate OpenAI intends to purchase Google’s Tensor Processing Units to diversify compute supply. This follows earlier TPU rental testing and hiring for TPU optimization, signaling a pragmatic shift toward multi-vendor silicon strategy amid tight supply. reuters.com/business/openai-… #AI #Semiconductors #OpenAI #GoogleTPU #TechStrategy
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Microsoft Azure Hits $33.2B (+48% YoY); Total Revenue $92.3B Azure’s first full dollar disclosure shows strong AI-driven cloud demand, outperforming guidance. Free cash flow also beat expectations, offering evidence that AI infrastructure spending is converting into revenue growth even as CapEx remains elevated. reuters.com/business/retail-… #AI #CloudComputing #Microsoft #TechInvesting #DataCenters
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Formation Bio Launches $600M AI Drug Development Accelerator Fund The AI-native pharma company (backed by Altman and others) raised a dedicated $600M fund to acquire and advance 10–15 Phase 1–2 drug programs via NewCos, pairing capital with its AI platform, translational models, and clinical ops. It targets the development bottleneck after discovery accelerates. formation.bio/blog/introduci… #AI #Biotech #Startups #DrugDevelopment #VentureCapital
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Anthropic IPO Filing: Explosive Growth Meets Massive Compute Costs Anthropic’s S-1 shows revenue up ~1,368% in one quarter (to multi-billion levels) alongside an $80.7B H1 net loss (largely non-operating) and $600B+ compute commitments. Valuation talk centers on $1.5–2T; Aswath Damodaran models ~$1.475T equity value. This is the clearest public test yet of AI-scale economics. reuters.com/legal/transactio… #AI #Anthropic #TechInvesting #IPO #AIEconomics
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Nanobubble oxygenation expands in commercial land-based salmon farming Andfjord Salmon is installing Moleaer nanobubble generators in two additional production pools at its Norwegian land-based facility after positive operational experience with oxygen management and system stability in the existing pools. moleaer.com/press-releases/a… #Nanobubbles #FineBubbles #Aquaculture #WaterTech #AdvancedMaterials
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Atomic-scale coatings company lists on Nasdaq Forge Nano (ticker NANO) completed its SPAC merger and listed on Nasdaq. Its Atomic Armor ALD platform applies uniform nanoscale coatings for higher yields in AI-era semiconductor manufacturing and improved battery cycle life/performance. It is ringing the Nasdaq opening bell today. morningstar.com/news/globe-n… #Nanotechnology #AdvancedMaterials #Semiconductors #Batteries #IPO
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Chipmakers buy equity in their largest AI customer Nvidia is investing $3B and AMD $1B into Meta’s roughly $95–97.5B equity raise to fund AI infrastructure. The suppliers are taking ownership stakes while Meta expands deployment of Nvidia Vera Rubin systems and related hardware. cnbc.com/2026/10/27/nvidia-i… #AI #Nvidia #Meta #Investment #Chips
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AI models independently refute the Exponential Time Hypothesis OpenAI and Anthropic both claim their models disproved the Exponential Time Hypothesis (a ~30-year computer-science assumption about 3-SAT hardness) on the same day (16 Oct), with Lean-verified proofs. Independent experts are reviewing; the result is sub-exponential, not polynomial, so it does not resolve P vs NP. newscientist.com/article/259… #AI #ScientificDiscovery #ComputerScience #ETH #OpenAI
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Anthropic’s S-1 exposes the real AI capital constraint Anthropic’s S-1 shows $16.3B H1 2026 revenue (≈14x YoY) and its first quarterly operating profit, while non-cancellable compute commitments reach hundreds of billions across Google, Amazon, Microsoft, Broadcom and others. The binding constraint is locked-in capacity, not the large accounting loss. anthropic.com/news/s1-sec
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