Ben retweeted
Kinetics of sevoflurane vaporized directly in #ECMO membrane lung
🔬ex-vivo trials using circuits primed with Ringer’s lactate; sevoflurane vaporized at concentrations of 1–8% with SGF of 1–10 L/min.
💨 sevoflurane effectively crossed PMP membranes, rapidly reaching reproducible peak concentrations to values consistent with clinical targets for deep sedation; clearance increased significantly with higher SGF
⚠️ environmental concentrations well below occupational safety thresholds
Delivering sevoflurane vaporized directly into ECMO circuits feasible/safe alternative sedative strategy. These results provide a robust foundation for translating this into pilot clinical trial aimed at optimizing ECMO sedation with inhaled sevoflurane in patients with severe ARDS.
🔓 rdcu.be/fk2xq
Ben retweeted
UK multisociety consensus statement on the emergency management and resuscitation of patients with left-sided Impella support
🫀Recognition of cardiac arrest
🏥 Team structure
🕵️ Early troubleshooting
heart.bmj.com/content/early/…
Ben retweeted
#ECMO following acute type A aortic dissection repair?
🔍 SR/MA
🪦 successful weaning 48.3%, but high in-hospital mortality = 72.4%; late mortality 5.8% per 100 pt/y
🫘 AKI requiring CRRT 60.5%
🧠 neuro complications due to stroke 24.4%
🦵🏻 limb ischemia 7.6%
🩸 bleeding requiring reoperation 29.2%
#ECLS may be reasonable. Despite high morbidity and mortality (comparable with other PC-ECLS), myocardial recovery may be achieved with careful patient selection: young patients better candidates; pre-ECMO lactate peak appears strong predictor for mortality.
@asaiojournal
🔗 bit.ly/4osNa
Ben retweeted
The @ERC_resus 2025 Guidelines are here!
These guidelines have helped inform the RCUK 2025 Guidelines which will be published on Monday 27 October at midday.
👏 The Wait is over
🚀 The 'ERC 2025 Cardio Pulmonary Resuscitation Guidelines' is Released.
🫀 Click the link to know more
👉 erc.edu/news/2025-erc-guidel…
#ERC #CPR #Guidelines2025 #ERCGuidelines #savelives #RESUS25
Ben retweeted
British societies guideline on management of emergencies in patients on ECMO
🫀Recognition of cardiac arrest
🏥 Team structure
🕵️ Early troubleshooting
@BritishCardioSo @FICMNews @ICS_updates @BACCNUK @SCTSUK @BSHeartFailure @ResusCouncilUK @ACTACCUK
link.springer.com/article/10…
Ben retweeted
The @ELSOOrg ECMO Bedside Guide is now available globally FREE open access for everyone interested in #ECLS! Honoured being among leads for 📋 Checklists & ⚠️ Panic button sections
Other topics
⚖️ assess candidacy
📦 equipment
🧮 calculators
💉 medications
📚 resources
📱 bit.ly/ELSOBedsideGuideA
📢 2️⃣ years & > 1️⃣0️⃣0️⃣ people from around ELSO world came together to create something useful for our community: ELSO's ECMO Bedside Guide, free, intended to be useful to everyone interested in #ECMO.
We are thrilled to make this available globally!
📱 bit.ly/ELSOBedsideGuideA
Ben retweeted
In Organ Donation Week, confirm your decision on the NHS Organ Donor Register, and share your wishes with your family and friends. You could save a life.
Go to organdonation.nhs.uk #OrganDonationWeek
ALT Graphic has the blue NHS logo in the top right corner, and a light pink heart below. There is a dark pink box with white writing which says: "Someone will die today waiting for an organ donation". Below that it adds: Most of us would accept an organ if we needed one. Two minutes now can save up to 9 lives. Confirm your decision on the NHS Organ Donor Register. It's tbe best thing you'll do today. Visit organdonation.nhs.uk.
Ben retweeted
Coronary, renal & cerebral perfusion of VA #ECMO + #IABP in refractory cardiogenic shock
🔬in vitro study
🫀hemodynamic effects depend on CO, HR, site of #ECLS arterial cannulation
If severe low CO, axillary artery (vs femoral) cannulation + IABP showed greatest benefit in terms of coronary/cerebral flow but renal perfusion negatively affected.
#FOAMcc #FOAMecmo @asaiojournal
🔓 bit.ly/4jnn7jQ
Ben retweeted
🎥 Recording of the webinar: Hot topics in NRP, perfusionist’s perspective, a joint @The_EBCP & @EuroELSO event, is now available, open access #FOAMcc at
🎥 youtube.com/watch?v=RPd5nugH…
We discussed about:
🔥 Who should manage NRP
🔥 The circuit: #ECMO, #CPB or hybrid?
🔥 What the ideal perfusion targets? How to monitor perfusion?
🔥 Education & training
#EuroELSOwebinar
Ben retweeted
One important point about differential hypoxemia:
People often think the R radial sat will be the first site to show drop. This isn’t true.
The first vessel to experience hypoxemia It’s the coronary arteries.
Watch for cardiac ischemia as a sign of differential hypoxemia!
Ben retweeted
2024 @EACTS @EACTAIC @The_EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery:
🎓 training, education & service delivery
🛠️ heart-lung machine hardware
📦 CPB disposables
🖥️ monitoring
🫀🧠🫘🫁 organ protection
⚙️ preparation for CPB
🩸procedures during CPB
🔍 CPB for specific techniques & specific situations during #CPB
✂️ separation from CPB
🚧 gaps in knowledge
🔑 key messages
Open access
🔓 bit.ly/3X06hz0
Ben retweeted
You all know Harlequin, now meet RIDDLER, ECMO’s newly named syndrome of differential decarboxylation in spontaneously breathing patients.
ahajournals.org/eprint/ZTN6H…
@FOAMecmo @iceman_ex @EchoSoliman @EduardArgudo @DYannopoulos @ECMOdaily @GomorraDoc @EuroELSO
Ben retweeted
Out now! Ep3 of the #THINKAORTA podcast re-unites survivor Anne Cotton with Dr. Martyn Bell, who diagnosed her acute #AorticDissection in @RoyalDevonNHS Barnstaple Hospital Emergency Department 9 years ago. Watch the full story here: youtu.be/MvHB_T34N9Q?feature… – at Norwich, England
Ben retweeted
Blood cell salvage & transfusion requirements after decannulation from VV #ECMO
🔎 841 pts, 2 🇬🇧 centers
🩸BCS decreased PRBC transfusion, no changes in inflammatory & coagulation markers, nor in transfusion of other blood products in 2 days
🔓 rdcu.be/d2DRy
Ben retweeted
Normothermic machine perfusion is increasingly used to approximate human physiology, preserve organs outside the body, provide dynamic graft assessment. Although NMP application is relatively new, its concept, foundation, development can be traced back to 1930s:
💡prototypical experimental surgeon-scientist
🩸Carrel & Lindbergh perfusion device
📜 legacy
💡 Carrel & Lindbergh’s lasting impression on NMP
@asaiojournal
🔗 loom.ly/pOGycXI
Ben retweeted
For shock patients you can always call our cardiorespiratory failure team and speak to a consultant 24/7 with options for retrieval if needed. Always happy to take ECMO/MCS referrals any time and we work closely with our cardiac colleagues
guysandstthomas.nhs.uk/refer…
Ben retweeted
Fantastic eCPR education half day for the South Thames ED regional training day. Lots learning for the participants and MDT faculty, great opportunity to refine process/kit for this challenging group of patients. Drowning/hypothermic cases challenging decision making @GSTT_ICU
Ben retweeted
Normothermic regional perfusion in DCD donors is ANYTHING BUT euthanasia!
🔓bit.ly/3wGV7VP
🪦circulatory determination of death is made using well accepted criteria
🩸procedures to regionalize perfusion are undertaken after death/before starting #NRP
🧠CBF is not restored during TA/A-NRP (moreover brain sustained prolonged no-flow anoxia, and eventually pre-existing injury)
🫀🫁🫘NRP resuscitates/recovers organs intended for #transplantation in as good a condition as possible (respecting an individual's decision to donate after death) & does NOT restore life itself
Just out on @JCVAonline, in reply to @JonahRubinMD
Ben retweeted
🚨Exciting update from the #ERC 2025 Committee! The ERC is including cardiac arrest survivors & patient organisations in the 2025 #resuscitation guidelines. 🚑💖 Need your help! 🙏 Reach out if you are connected to cardiac arrest survivor groups or patient organisations. Let's make ERC 2025 guidelines inclusive & patient-focused.
📢 Spread the word & mail us your contacts at [email protected]. Together, we can save lives! #CardiacArrestAwareness #PatientInclusion #CollaborateForChange #ERCGuidelines2025 #RESUS24
