Senior Principal Investigator at New England Biolabs and Honorary Professor at Durham University. Views my own. He/him.
New England Biolabs, MA
Joined September 2020
- Tweets220
- Following1.4K
- Followers1.8K
- Likes543
Tim Blower retweeted
You can now apply for a #ListerPrize2027 Research Fellowship.
£300,000 flexible funding to support outstanding early-career researchers within the biomedical sciences field based in the UK and Ireland.
All details 👉 lister-institute.org.uk/rese…
Tim Blower retweeted
Phages invented sgRNAs before humans!!
Obviously, for mischief… 😈
Loved seeing this story unfold!
biorxiv.org/content/10.64898…
Tim Blower retweeted
NEB researchers systematically screened 186 MazF homologs, identifying >130 active endoribonuclease with diverse sequence preferences. Read more about how Tth-MazF1 can be a powerful tool for RNA analysis in Nucleic Acids Research: doi.org/10.1093/nar/gkag338
Tim Blower retweeted
Rejection is part of science. So is resilience. 🔬
@BlowerLab and @CJStewart7 share how setbacks helped shape their careers. We don't talk about this enough.
🔁Please repost and share your own stories of defeat or bouceback. Break the stigma!
lister-institute.org.uk/news…
ALT Head and shoulder photos of Chris Steward (left) and Tim Blower (right). Both are wearing dark navy jackets and navy ties against blurred backgrounds.
Tim Blower retweeted
We are delighted to host Professor Tim Blower @BlowerLab as keynote speaker to our MID symposium
@WarwickLifeSci
Date: 20th of June Venue: GLT1 We invite MBio, PhD students and Postdocs to submit abstracts for posters and talks by 11th of June to
@CRodriguesLab
Tim Blower retweeted
For those of you who approached me at @MicrobioSoc #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
Tim Blower retweeted
The final version of our Serratia paper is now out! Congrats to @TomCX99 and (X-less) Suraj, and a big thank you to @BlowerLab and @StephenRG97. tinyurl.com/3vnyvufa
New pre-print from the lab, led from (for now Twitter-less) star-RA Tom Cummins. If you did receive his PhD application, you do not want to miss this chance, Tom is a star!
As always, fun collaboration with the amazing @BlowerLab and @StephenRG97
Tim Blower retweeted
Over the moon to share some amazing news—I’ve been awarded an MRC Career Development Award to pursue my research at the University of Glasgow @UofGSii ! 🎉 Can’t wait to get started on this exciting new chapter. Stay tuned—I’ll soon be advertising a PDRA position!
Tim Blower retweeted
Using cryoEM we understood the structural basis of chiral DNA wrap by bacterial gyrase (and also produced the most complete/highest resolution E coli gyrase model to date).
@JohnInnesCentre @DurhamU34989 @MCB_UJ
Tim Blower retweeted
Thrilled to share my latest postdoc paper published in
@NatureComms
NTase toxin targeting serine tRNA 3'-ends by CMP addition in M. tuberculosis H37Rv. Thanks to all the co-authors,
@GenevauxPierre
@BlowerLab
@ONeyrolles
rdcu.be/dZle4
Tim Blower retweeted
When experiments don’t work... build a phage costume! 🎃
Happy PHAGEOWEEN!!! 👻🧬#Teamwork
Tim Blower retweeted
journals.asm.org/doi/10.1128…
Our thoughts on how toxins bound to TAs are activated: via conformation changes, not by selective degradation of ATs by a protease (makes little sense since both are structured). Remarkable insights determined by studying various TAs as they inhibit phage.
Tim Blower retweeted
Researchers @blowerlab and colleagues use biochemistry, biophysics, and crystallography to characterize a mechanism of antitoxin induced autophosphorylation that can neutralize nucleotidyltransferase toxins of Mycobacterium tuberculosis
nature.com/articles/s41467-0…
Tim Blower retweeted
Congratulations to @BlowerLab and @tomarrow234
Happy to be involved in this wonderful collaboration!
NTase toxins are truly amazing!
Dissecting the antitoxin-mediated Toxin auto-phosphorylation
rdcu.be/dSXxi
Tim Blower retweeted
My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses.
(👇 I recommend sound ON for the video 🎹)
1/
Tim Blower retweeted
A #PDRA position in #evolutionary #microbiology is available in the lab of Dr James Hall (UoL) as part of a BBSRC project in collaboration with the MultiDefence Consortium (sites.exeter.ac.uk/multidefe…)
Information/Apply tinyurl.com/3p85rrtw
@LivUniHLS @LivUni_IVES @LivUniResearch
Tim Blower retweeted
🚨 JOB ALERT 🚨
Join the @Multi_Defence consortium as a postdoctoral researcher within my lab @UniofBath. The project will aim to understand the regulation of multiple bacterial defence systems.
Apply here by 9th Sept: bath.ac.uk/jobs/Vacancy.aspx…
@lifesciencebath @MilnerCentre
Tim Blower retweeted
Keep watch… plenty starting to happen with the #CRISPR conference in NZ next February.
Get ready for #CRISPR2025 in #NewZealand. We are fortunate to have Malcolm White @mfwhite2 as our Keynote speaker.
Tim Blower retweeted
Amazing new method that enabled us to determine this Aca2 structure. Keep your eyes peeled 👀 for the paper on the biology and mechanism due to drop next month…
This quoted post is unavailable.
Tim Blower retweeted
Recently, a few cool papers have revealed defence system synergies 🛡️🤝🏻🛡️ – for example by the @MarraffiniLab (cell.com/molecular-cell/full…) and the @BlowerLab (academic.oup.com/nar/article…).
However, our study illustrates that defence systems can also be mortal enemies! 🛡️☠️🛡️ [11/n]
