CPPopt retweeted
The President’s Commendation for a sustained contribution to the College was presented to Dr Rana Hafiz Ur Rehman.
Dr Ari Ercole gave the Macintosh Professor Lecture. Seen here with President Dr Claire Shannon and Prof Iain Moppett.
Read more: ow.ly/NsKo50UeHFx
ALT HRH The Princess Royal presenting the President’s Commendation to Dr Rana Hafiz Ur Rehman.
ALT Dr Ari Ercole holding a certificate for the Macintosh Lecture with President Dr Claire Shannon and Professor Iain Moppett.
CPPopt retweeted
Wonderful news for a remarkable colleague, friend, and doctor.
Following recommendations from @NIAAResearch, we are pleased to announce that 2 Macintosh Professorships have been awarded.
@RonelleMouton - RCoA & VASGBI Macintosh Professor
@AriErcole - RCoA Macintosh Professor
Congratulations both.
ow.ly/4W9m50QoPzW
ALT Pictures of Dr Ronelle Mouton, Honorary Associate Professor of Anaesthesia, Translational Health Sciences, Bristol Medical School and Dr Ari Ercole an anaesthetist and intensive care physician, holding a substantive consultant post in neuroscience and intensive care medicine at Cambridge University Hospitals NHS Foundation Trust.
CPPopt retweeted
Traumatic brain injury #TBI phenotypes from @CenterTBI #ICU data by probabilistic time-series clustering
𝗧𝗲𝗺𝗽𝗼𝗿𝗮𝗹 𝘃𝗮𝗿𝗶𝗮𝘁𝗶𝗼𝗻 of brain injury 𝗯𝗶𝗼𝗺𝗮𝗿𝗸𝗲𝗿𝘀 = missing link in describing the 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹 course
authors.elsevier.com/c/1i5LY…
@TheLancetNeuro
CPPopt retweeted
ICP is strongly confounded by therapeutic intensity level (TIL) after #TBI. Measuring TIL crucial to understand severity
Various TIL scores validated in @CenterTBI doi.org/10.1089/neu.2023.037…
@TBI_data_guy nails TIL representing 'refractory' ICP:
TILᵐᵉᵈ≥7.5
CPPopt retweeted
A solution to the age-old problem of where to zero the transducer in neurocritical care...
rdcu.be/dlTOs
doi.org/10.1007/s12028-023-0…
CPPopt retweeted
Does what happens in #ICU stay in ICU after #TBI?
Well done @TBI_data_guy for time-series #machinelearning model ingesting 𝑎𝑙𝑙
@CenterTBI data with minimal pre-processing looking at contribution of clinical course events to outcome in
@npjDigitalMed
nature.com/articles/s41746-0…
CPPopt retweeted
Precision medicine to improve outcome after traumatic brain injury: data-driven approaches to identify pathophysiological or pathobiological mechanisms to individualize treatments
🧠suggestions for #TBI phenotypes
🧠methodological considerations
#FOAMcc
🔓 rdcu.be/dhtsr
CPPopt retweeted
Machine learning and novel algorithmic techniques show great potential, but need to be applied and interpreted correctly
Right question+right data+right method
doi.org/10.1038/s41591-022-0…
@CC4AIM
CPPopt retweeted
Unsupervised clustering in @CenterTBI finds 6 stable endotypes of #TBI in the #ICU
⚠️Systemic metabolic stress important differentiating patients as well as traditional GCS classification
doi.org/10.1186/s13054-022-0…
rdcu.be/cSxc0
CPPopt retweeted
#TraumaticBrainInjury research often dichotomises outcomes. Here's how to handle ordinal outcomes from @shubhayu_neuro including a #machinelearning approach using 𝙖𝙡𝙡 the @CenterTBI features for best prediction
doi.org/10.1371/journal.pone…
CPPopt retweeted
Some 𝘷𝘦𝘳𝘺 important things to know about the challenges of large-scale observational data collection in #TBI from @CenterTBI
doi.org/10.1007/s12028-022-0…
CPPopt retweeted
Primary analysis of @global_neuro Global Neurotrauma Outcomes Study #GNOS published tonight @TheLancetNeuro.
thelancet.com/journals/laneu…
Phenomenal collaboration of clinicians from 57 countries 🌍.
#WFNS2022 #globalneurosurgery #globalneurotrauma #TBI
CPPopt retweeted
Yes, and Cogitate study is one of the most read papers in 2021!!
Check out the most read papers from Journal of Neurotrauma. liebertpub.com/action/showMo…
CPPopt retweeted
Glasgow Coma Score & pupil reactivity=crucial #TBI outcome determinants but timepoints frequently missing in real-world data
Evaluation of methods for effective imputation by @CenterTBI...
... the answer depends on the question!
doi.org/10.1371/journal.pone…
CPPopt retweeted
There are many linear & non-linear methods for detecting causal relationships between signals. Which to use?
➡️turns out not all as robust as each other
Caveat emptor!
Mathematical review with code by @tedinburgh_
doi.org/10.1063/5.0053519
Code doi.org/10.5281/zenodo.47208…
CPPopt retweeted
2️⃣ Individualising care of severe #TBI in the #ICU using autoregulation-guided precision care: the #COGITATE study from @AriErcole and also @aries_marcel , @DrSmielewski @GMeyfroidt and the @CPP_opt team at #naccs2021. One size does not fit all!
CPPopt retweeted
DeepClean: a self-supervised algorithm to detect artefacts in physiological waveform data using Deep Generative Learning
Well done @tedinburgh_ and thanks to @CCIMathInfo
doi.org/10.1007/978-3-030-59…
CPPopt retweeted
𝘊𝘢𝘷𝘦𝘢𝘵 𝘦𝘮𝘱𝘵𝘰𝘳...
Not all methods for determining causality between time-series behave the same, as nicely demonstrated in this preprint by @tedinburgh_
arxiv.org/abs/2104.00718
CPPopt retweeted
Large variation in how #ICUs use aggressive treatments for #TBI
But patients who require 'high intensity' treatments can still have good outcomes: Such treatments should be chosen carefully however
No place for nihilism!
ccforum.biomedcentral.com/ar…
doi.org/10.1186/s13054-020-0…
