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The world's most painful condition demands urgent action. Help us accelerate access to the most effective therapies for cluster headaches.

Joined April 2025
Since launching ClusterInfo.org 8 weeks ago, the site has been read by over 3,000 people across 80+ countries and 8 languages, with no ad spend (yet). Help us reach more patients by sharing it (or, if you have a website, linking to it, which helps patients find us).
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How much did the NIH spend on cluster headache in 2024 relative to other similarly prevalent conditions? Narcolepsy: $10M Cluster headache: $0.5M Funding to prevent the worst pain a human can experience is a rounding error. This needs to end.
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New in Neurology: Results from international survey on DMT for cluster headache. 67% said DMT completely eliminates pain from attacks - most within 30 seconds. Research by Dr. Schindler at Yale & Clusterbusters. 📄 Study: neurology.org/doi/10.1212/WN…
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"An honest conversation about life with one of the most painful conditions known to medicine... The challenges, the isolation, the resilience it takes to keep moving forward, and the importance of finding people who truly understand."
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New results on DMT for cluster headache. "Among those who used DMT to abort attacks (n = 85), the majority reported it completely eliminates pain (67.5%) and that it works every (45.7%) or almost every (35.8%) single time. Over half reported that DMT worked in under 30 seconds"
Published in Neurology, "the most widely read and highly cited peer-reviewed neurology journal", on June 9 2026 Results From a total 248 completed surveys, 100 participants met criteria for cluster headache. Of these, 84% were male and average age was 49 years. The most common place to have learned about DMT treatment was social media/online. More than one mode of ingestion was often tried, but 75% had used a vape pen. Among those who used DMT to abort attacks (n = 85), the majority reported it completely eliminates pain (67.5%) and that it works every (45.7%) or almost every (35.8%) single time. Over half reported that DMT worked in under 30 seconds, and all participants reported either no change or an improvement in their health with DMT use.
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Today we're launching ClusterInfo.org: High-quality, multilingual guides on cluster headache treatments, for patients, caregivers, and doctors looking for reliable information on what actually works. clusterinfo.org/?utm_source=…
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Our goal with ClusterInfo is to reach thousands of patients and help them find effective treatments faster, especially in countries where little information is available. We will publish more guides and translate the website into more languages in the coming weeks.
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How to help: - Take the patient survey if the guides help you: clusterinfo.org/en/survey - Share with anyone who could benefit - Give us feedback on the guides and their translations (easily done via the website) - Donate to ClusterFree: clusterfree.org/about#donate
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Treating cluster headaches with 5-MeO-DALT: Tommy Young's testimonial "5-MeO-DALT has definitely given me my life back." youtube.com/shorts/phfiIAxgU…
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Tommy is a chronic cluster headache patient (since 2021) from Scotland. After standard pharmaceutical treatments failed to treat his clusters, Tommy has found relief in psychedelic medicine. LSD brought some relief, but 5-MeO-DALT has been a life-saver.
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Tommy also uses N,N-DMT to abort attacks when they're getting more severe; the pain goes away within minutes.
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Mark, chronic cluster headache patient, shares his experience using DMT. "It's very effective, very fast. I don't like the ride afterwards, but you do come back quickly. And it stops the pain immediately." youtube.com/shorts/ZnGFn-RjN…
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"And that pain is so intense, there's no way to describe what that is to the normal person. […] You don't really know what pain is until you've had CH. DMT gives you some peace of mind of being out of that pain quickly."
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Gracias a @ArturoGP_ por este video sobre la cefalea en racimos y el trabajo que estamos haciendo con ClusterFree! youtube.com/watch?v=SZa34RLz…
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My article “Near-Instantly Aborting the Worst Pain Imaginable with Psychedelics”. It's about ClusterFree — @QualiaRI's initiative for cluster headache patients. Co-founded by @algekalipso and @alfredoparrah As much of it as fits is in the screenshots. The link → next tweet.
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Why are the best treatments for one of the most painful conditions known to medicine illegal? Philosopher @PeterSinger discusses cluster headaches in his latest Project Syndicate column, and urges readers to sign our open letters. We can change this. Read the column below.
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