🇵Postdoc @RIMLS_Science. Using iPSCs to understand and find treatments for 👁 diseases.Currently focusing on #aniridia and all things PAX6. Previously @UCLeye.
London, England
Joined June 2018
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Congratulations @Suz_Stelloo!👏👏 Looking forward to your talk on Saturday!
@RIMLS_Science @Radboud_Uni
On my way to beautiful Stockholm to attend the European Aniridia Conference 2024 @AniridiaEurope. Looking forward to presenting my latest work from @JoHZhou_Lab and meeting so many colleagues and friendly faces again!
Dulce Cunha retweeted
Be a Research Fellow & fight rare eye disease!
@mariyamoosajee seeks talent for RLBP1 gene therapy. Develop treatments using stem cells & advanced tech. PhD & experience req. Apply by May 22 bit.ly/3UYmuEd #RetinaResearch #GeneTherapy #JobAlert
Couldn't miss #RareDiseaseDay! Very proud to be part of a community of researchers & clinicians who study #aniridia 👁️
In my current NWO Off Road Grant @RIMLS_Science, I grow #cornea #organoids from patients stem cells to find out how the cornea is affected and how to treat it.
Dulce Cunha retweeted
🚨 IT'S RARE DISEASE DAY GLOBALLY! 🚨 Join us marking #RareDiseaseDay 2024! Spread awareness, share stories, and support those living with rare diseases. Together, we make a lasting impact! #ShareYourColours
It was a pleasure! Looking forward to present more work on aniridia at the #EuroAniridiaConf in May. Hope to see you all there!
Another excellent speaker from our #ANUKConf last year was @DLimaCunha, who shared the results of her study demonstrating that #Amlexanox rescues #PAX6 levels in #aniridia stem cell-derived models. Find out more and watch her presentation here:
aniridia.org.uk/2024/02/26/a…
Dulce Cunha retweeted
We are glad to share with you all, the extensive list of speakers and their abstracts for the EAC 2024. With about 30 speakers and topics covering a wide range of perspectives connected to aniridia this conference will be of highly scientific interest! 👉aniridiaconference.org/eac20…
New paper from @JoHZhou_Lab out in @PLOSBiology! We performed a big multi omics study that identified novel TFs interplay required for limbal epithelial stem cell identity and showed new TF #FOSL2 involvement in #cornea disease. ⬇️
@RIMLS_Science
Multiomic comparison of #LimbalStemCells (maintain the #cornea) with #keratinocytes (maintain the #skin) reveals an intriguing interplay of TFs that drive #epithelial similarities & differences in health & disease @JoHZhou_Lab @svheeringen #PLOSBiology plos.io/3rYksbG
Always a pleasure to attend #ANUKconf and present past and future #aniridia projects. Thank you @AniridiaNetUK for the kind invitation and hope to see you next year at the @AniridiaEurope meeting!
So happy my past main project in @MariyaMoosajee group @UCLeye is out! We generated iPSC-derived retinal and corneal models from #aniridia patients and dosed with nonsense supression drugs. We propose #amlexanox as a promising candidate for rescuing #PAX6 defects in these models.
Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs #MTNA dlvr.it/SrK0PS
This was such challenging work with lots of effort and teamwork!💪 Wouldn't have been possible without all the help and support from other authors Hajrah Sarkar, @PhilippaHarding @JEintracht @JoHZhou_Lab and of course the guidance and belief of @MariyaMoosajee! Thank you all!!
Dulce Cunha retweeted
Read this. Worth 5 minutes of your time.
It matters who does science science.org/content/blog-pos…
Saying goodbye to #NewOrleans after an amazing week at @ARVOinfo #ARVO2023! So much great work and lovely to chat with so many people doing amazing science. Lots of new ideas for the return to the lab!
And the city and the food? Amazing!!
Dulce Cunha retweeted
Fantastic @womeninvisionuk social @ARVOinfo. Thanks to all who joined, its so great to see so many brilliant academics at all stages of their career representing UK talent at #ARVO2023 in New Orleans!
Dulce Cunha retweeted
Today, it will be my turn to present my work about retinal organoids as model for #RDH12-associated retinopathies! Come to see my poster C0387 from 11.45 or at "all poster" session! A beautiful work with @MariyaMoosajee @Dr__NO @Lyes_Toualbi & Hajrah Sarkar! @UCLeye @TheCrick
ALT Screenshot of ARVO app which presents details to see my poster: C0387: Characterisation of induced pluripotent stem cells derived retinal organoid models of RDH12-retinopathies. Tuesday 25th April. 11.45-1.30. Session #178 Cécile Méjécase (University College London) Location - Exhibit Hall
Congratulations @DorsaAbdolkarim for this much needed review on #aniridia disease models! Very glad to have contributed 🙂
Big shout out to @DorsaAbdolkarim from @UniofBath who joined my lab @UCLeye last year to undertake her BSc research project- she has published her first paper on #PAX6 disease models for #aniridia 🥳
Read 👉🏼journals.lww.com/ijo/Fulltex…
#WellDone #FridayFeeling @womeninvisionuk
The preprint of my main project with @MariyaMoosajee @UCLeye is out on bioRxiv. We tested several readthrough drugs on novel #aniridia iPSC-derived retinal #organoids & #cornea models. We 💪 to move forward with possible treatments for patients. Peer-review is ongoing 🤞
Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs biorxiv.org/cgi/content/shor… #bioRxiv
Thank you very much to the other authors @JEintracht @PhilippaHarding @JoHZhou_Lab for your hard work and assistance throughout this challenging project!