RT @DjuranovicLab: Ready for three scientific weeks and RNA in Japan. Going from tRNA meeting
trna2024kanazawa.jp/
in Kanazawa to Molecu…
Lucy Dimitrova-Paternoga retweeted
Now out in peer-reviewed format at @nchembio …rdcu.be/dXhoi
Our preprint reporting the structure and mechanism of the natural product translation inhibitors paenilamicins is out…completely novel binding site on the ribosome! dlvr.it/T7CNnf…great collaboration with @Suessmuth_Lab @shuramankin
Lucy Dimitrova-Paternoga retweeted
Excited to share our latest research on co-translational mRNA decay by the exosome in human cells! We uncover how the exosome-SKI complex is recruited to ribosomes and propose a novel role for SKI in recognizing collided disomes. @MPI_Biochem
👇👇👇
Lucy Dimitrova-Paternoga retweeted
1/ 🚨 New Paper Alert! Our latest research in bioRxiv uncovers how translation inhibitors kasugamycin, edeine, and GE81112 target different steps in bacterial translation initiation, offering high-resolution insights into their mechanisms. 🧬🔬 #StructuralBiology #CryoEM
Our latest work on structures of translation initiation complexes trapped by natural product inhibitors kasugamycin, edeine and GE81112 is out in the Biorxiv…biorxiv.org/content/10.1101/…
Lucy Dimitrova-Paternoga retweeted
Our results finally explain the essential role of snR30 snoRNA! Check out the details in our preprint to find out more 👉👉👉 biorxiv.org/content/10.1101/…
#ribosome #cryoEM #RNA
Lucy Dimitrova-Paternoga retweeted
Our collaboration with @WilsonLab2 and @vpelech is out in @NAR_Open! The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site
academic.oup.com/nar/advance…
Lucy Dimitrova-Paternoga retweeted
Excited to be elected as @RNASociety Director! Congrats to co-elected Directors @AndrzejDziembo1 and @BeAScientist, and President-Elect Fatima @GebauerLab!
Congratulations Fátima Gebauer (Centre for Genomic Regulation, Spain) on being elected as President-Elect of the RNA Society! Fátima will serve as RNA Society President for the two-year term spanning 2025-2026.
Congratulations also to Marina Chekulaeva (Berlin Institute for Medical Systems Biology, Germany), Andrzej Dziembowski (International Institute of Molecular and Cell Biology, Poland), and Olivia Rissland (University of Colorado, USA) who were elected to serve as RNA Society Directors for the two-year term spanning 2025-2026!
Lucy Dimitrova-Paternoga retweeted
Finally, out!
MFSD1 functions as a general dipeptide uniporter in lysosomes!
This was a real team effort. Many thanks to @Kathaschnatta, @DammeMarkus, @OceaneGuelle and Bruno Gasnier, @AhmadRezaMehdi1, @abu_remaileh, and everyone else involved!
See: doi.org/10.1038/s41556-024-0…
Lucy Dimitrova-Paternoga retweeted
Our latest submission to @biorxivpreprint is now available online:
biorxiv.org/content/10.1101/…
A joint effort between Harpreet, Jutta, and Asen, and our previous rotation students Eric, Christian, David, Katalin, Daniel, and Felix @UniHeidelberg
@biorxiv_biochem @dfg_public
Lucy Dimitrova-Paternoga retweeted
Out in @NAR_Open! A transcontinental consortium involving @WilsonLab2 @gem__atkinson and other ribosomal aficionados establishes YlmH as a new ribosome-associated quality control (RQC) factor in Bacillus subtilis! academic.oup.com/nar/advance…
Congratulations!!!
Out in @NAR_Open! A transcontinental consortium involving @WilsonLab2 @gem__atkinson and other ribosomal aficionados establishes YlmH as a new ribosome-associated quality control (RQC) factor in Bacillus subtilis! academic.oup.com/nar/advance…
Lucy Dimitrova-Paternoga retweeted
Together with @WilsonLab2 and @pelechanolab we show that yeast ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site.
biorxiv.org/content/10.1101/…
Lucy Dimitrova-Paternoga retweeted
#RNA24 is finally here! Keynotes in Pentland Auditorium
Lucy Dimitrova-Paternoga retweeted
Our preprint reporting the structure and mechanism of the natural product translation inhibitors paenilamicins is out…completely novel binding site on the ribosome! dlvr.it/T7CNnf…great collaboration with @Suessmuth_Lab @shuramankin
Lucy Dimitrova-Paternoga retweeted
Special credit to first authors @TimmKoller and Max Berger. Also thanks to @shuramankin for hosting Max in Chicago to complete some experiments for this project and to Bertrand Beckert from @DCI_EM for great cryoEM data as always.
Our preprint reporting the structure and mechanism of the natural product translation inhibitors paenilamicins is out…completely novel binding site on the ribosome! dlvr.it/T7CNnf…great collaboration with @Suessmuth_Lab @shuramankin
Lucy Dimitrova-Paternoga retweeted
bioRxiv: Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis dlvr.it/T7CNnf
Lucy Dimitrova-Paternoga retweeted
Structural mechanism of angiogenin activation by the ribosome | Nature nature.com/articles/s41586-0…
Cool stuff from the Plaschka lab (@plaschka_lab). Finally some mechanistic insight into the connection between the TREX and the TREX-2 complex. Bravo! biorxiv.org/content/10.1101/…
Lucy Dimitrova-Paternoga retweeted
Thrilled to finally share the work from my PhD where we performed cryo-ET on C. elegans centrosomes. A short thread follows:
biorxiv.org/content/10.1101/…
Lucy Dimitrova-Paternoga retweeted
Our (Helge Paternoga and myself) Biospektrum review now out in English…biospektrum.de/magazinartike…
As a scientific society, we want to be open to all scientists who conduct research in Germany and are interested in becoming members, including those who do not speak German. What do you think of "English as an option" for @Spektrum_BIO? We look forward to your comments!





















