@EricGreerLab

We are a lab studying the molecular mechanisms of epigenetics and how epigenetics impacts a variety of biological processes and diseases

 Wash U in St. Louis
thegreerlab.com/
Joined June 2019
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  • Followers2K
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18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis dlvr.it/SwTBv5

18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis

Liberman et al. labeled and tracked heritable non-genetic information from parents to their children. They identified that m6,2A methylated rRNAs are transmitted across generations in response to...

cell.com
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Online Now: 18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis dlvr.it/SvzgwS

18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis

Liberman et al. labeled and tracked heritable non-genetic information from parents to their children. They identified that m6,2A methylated rRNAs are transmitted across generations in response to...

cell.com
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🚨Postdoc alert🚨 My group at the Leibniz Institute on Aging in Jena is looking for postdoc candidates to study microbiome dynamics during host-aging. jobs.leibniz-fli.de/jobposti…
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Happy to see the preprint of the work I collaborated with during my postdoc at @EricGreerLab finally out! 🙌🏻 NOP16, a histone mimic protein that regulates H3K27me3 in breast cancer. biorxiv.org/content/10.1101/…

NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression

Post-translational modifications of histone tails alter chromatin accessibility to regulate gene expression. Some viruses exploit the importance of histone modifications by expressing histone mimetic...

biorxiv.org
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The Oberdoerffer lab is expanding in size and scope! Please apply if you are interested in pursuing a postdoc in RNA modifications and the development of cancer therapeutics. nature.com/naturecareers/job… #jobs

Postdoctoral Fellow: RNA Epigenetics and Therapeutics - Bethesda, Maryland

Fully-funded postdoctoral position to examine the regulation of protein translation through mRNA modifications and development of novel therapeutics.

nature.com
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Last year, the same author team tackled adenine methylation in DNA (6mA) and adenine methylation in RNA (m6A) in two separate reviews:
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Means, mechanisms and consequences of adenine methylation in DNA go.nature.com/3tFz1gS #Review by Konstantinos Boulias & @EricGreerLab @BostonChildrens @harvardmed

Means, mechanisms and consequences of adenine methylation in DNA

Nature Reviews Genetics - In this Review, Boulias and Greer provide an overview of current approaches for detecting and mapping N6-methyl-2′-deoxyadenosine (6mA or m6dA), and discuss the...

nature.com
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Biological roles of adenine methylation in RNA go.nature.com/3grXEeo #Review by Konstantinos Boulias & @EricGreerLab @BostonChildrens @harvardmed

Biological roles of adenine methylation in RNA

Nature Reviews Genetics - Boulias and Greer review the functions of N6-methyladenosine (m6A) in RNA at the molecular, genomic and organismal level. They describe the impact of m6A deposition on RNA...

nature.com
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Eric Greer Lab retweeted
LabAnimal@LA_NatRes19 Apr 2023
New online│ News and Views by Eric Lieberman Greer (@EricGreerLab) on the study by Takahashi et al. in @CellCellPress reporting a new mouse model with directed DNA methylation to study transgenerational epigenetic inheritance in mammals. nature.com/articles/s41684-0…
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Eric Greer Lab retweeted
MS NOW
@MSNOWNews6 Apr 2023
Tennessee state Rep. Justin J. Pearson slams Republicans for effort to expel lawmakers over anti-gun violence protest: "It is no coincidence that the two youngest Black lawmakers in the state of Tennessee, and one of two women are on trial today. That is not accidental."
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Eric Greer Lab retweeted
Nature Aging@NatureAging23 Jan 2023
See the associated 💡 News&Views by Eric Lieberman Greer doi.org/10.1038/s43587-022-0…

Deadly males accelerate aging with piRNAs

Nature Aging - Mating is known to accelerate the aging of the opposite sex in a variety of species. A transcriptomic analysis of extracted germlines from mated and unmated Caenorhabditis elegans by...

nature.com
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Eric Greer Lab retweeted
Cell Reports@CellReports19 Dec 2022
Hypoxia induces transgenerational epigenetic inheritance of small RNAs dlvr.it/SfdFVF
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Biological roles of adenine methylation in RNA go.nature.com/3grXEeo #Review by Konstantinos Boulias & @EricGreerLab @BostonChildrens @harvardmed

Biological roles of adenine methylation in RNA

Nature Reviews Genetics - Boulias and Greer review the functions of N6-methyladenosine (m6A) in RNA at the molecular, genomic and organismal level. They describe the impact of m6A deposition on RNA...

nature.com
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The promises and pitfalls of specialized ribosomes dlvr.it/SSScdW

The promises and pitfalls of specialized ribosomes

The concept of specialized ribosomes has garnered equal amounts of interest and skepticism since it was first introduced. We ask researchers in the field to provide their perspective on the topic and...

cell.com
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Eric Greer Lab retweeted
Valenzano Lab@valenzanolab9 May 2022
🚨 Postdoc position alert Our lab is looking for a postdoc to work on the microbiome:host immune axis during aging. Join us in Jena at the Leibniz Institute to do groundbreaking work and address fundamental questions in biology of aging.
Leibniz-Institut für Alternsforschung (FLI)@LeibnizFLI9 May 2022
Looking for #postdoc position in #agingresearch and #immunology🐟? @valenzanolab @LeibnizFLI in #Jena 🇩🇪is inviting applications for DFG funded project👉jobs.leibniz-fli.de/jobposti… @PostdocPhd @PostdocP @UniJena @jobRxiv @academics_de @ResearchGate @DFG_public #jobsinscience
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Eric Greer Lab retweeted
Harvard University
@Harvard16 Apr 2022
A study led by researchers at @harvardmed and @BostonChildrens explains why COVID-19 causes severe inflammation in some people, leading to acute respiratory distress and multi-organ damage hms.harvard.edu/news/inflamm…

Inflammatory Insights

Study reveals how COVID-19 triggers severe immune response

hms.harvard.edu
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We're hiring! 🧵👇🏽 1/4 We're looking for an experimentally-minded postdoc interested in exploring the interplay between host aging and age-dependent microbiota changes in our experimentally accessible, naturally short-lived African turquoise killifish (Nothobranchius furzeri).
Valenzano Lab@valenzanolab11 Apr 2022
We have openings a many levels (from postdoc to master student). Join us to: - explore the crosstalk between aging of the immune system and the microbiome - chart the microbial ecology of killifish populations in nature valenzano-lab.github.io/labs…
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Means, mechanisms and consequences of adenine methylation in DNA go.nature.com/3tFz1gS #Review by Konstantinos Boulias & @EricGreerLab @BostonChildrens @harvardmed

Means, mechanisms and consequences of adenine methylation in DNA

Nature Reviews Genetics - In this Review, Boulias and Greer provide an overview of current approaches for detecting and mapping N6-methyl-2′-deoxyadenosine (6mA or m6dA), and discuss the...

nature.com
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Eric Greer Lab retweeted
Julien Sage@SageJulien23 Nov 2021
Please RT: faculty position at Stanford! PhD, MD, MD/PhD candidates in the broadly-defined fields of pediatric cancer or stem cell transplant, laboratory and/or computational research programs welcome. Amazing environment! Feel free to contact me + check: app.smartsheet.com/b/form/ac…
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We are currently recruiting for a Ph.D fellowship position! Candidates would pursue computational projects to develop methods for study aging in high-dimensional data describing changes across cells, individuals, and populations. Contact me with a C.V. and statement of purpose.
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