A peer-reviewed, open-access online journal with no APC (Indexed in ESCI, Scopus, Google Scholar, DOAJ, CAS), COPE member E-mail: [email protected]
Joined October 2021
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Exploration of Neuroprotective Therapy retweeted
ARES Review System supports fast, transparent, and high-quality peer review across Open Exploration journals.
🔹 Intelligent reviewer matching
🔹 Global expert network
🔹 Reviewer recognition & rewards
Advancing scientific publishing through innovation.
aressystem.com/Index/HowItWo…
Exploration of Neuroprotective Therapy retweeted
📢 CALL FOR PAPERS
Special Issue: Breakthroughs in Mechanisms and Treatments for Neurodegenerative Diseases
explorationpub.com/Journals/…
🎁Benefits
No APC before July 31, 2026
Indexed in Scopus, Google Scholar, DOAJ, CAS, etc.
Chance to win the "Highly Cited Paper Award" ($300-$1000)
Exploration of Neuroprotective Therapy retweeted
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration @NatureNeuro
nature.com/articles/s41593-0…
Exploration of Neuroprotective Therapy retweeted
Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing - The Lancet thelancet.com/journals/lance…
Exploration of Neuroprotective Therapy retweeted
This is the most comprehensive review on Alzheimer’s and inflammation I’ve read in a long time. Highly recommended for anyone interested in learning about AD research or future therapeutic possibilities in AD.
nature.com/articles/s41577-0…
Exploration of Neuroprotective Therapy retweeted
Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans: Cell Metabolism cell.com/cell-metabolism/abs…
Exploration of Neuroprotective Therapy retweeted
The macrophages that pretend to be a neuron 🤣🤣🤣take a look at our study published in Nature and see how macrophage exert ms modulation of sensation and action via glutamate. Fantastic collaboration with @digiovannilab @LabPerrier
nature.com/articles/s41586-0…
Exploration of Neuroprotective Therapy retweeted
Scientists may have discovered why ApoE4 causes Alzheimer’s disease and ApoE2 prevents it. Hint: the reasons are different. @Denalitx ow.ly/vMyS50Ukn90
Exploration of Neuroprotective Therapy retweeted
nature.com/articles/s41380-0…
Very exciting paper - still need to go through all of it, but already liked the use of cOpn5 to stimulate astrocytes. Potentially interesting if ATP and glutamate are released through independent mechanisms
Exploration of Neuroprotective Therapy retweeted
Our paper hot off the press in @alzdemjournals shows APOE4 carriers have blood-brain barrier breakdown even *before* amyloid accumulation or cognitive impairment, which correlates with microstructural damage. alz-journals.onlinelibrary.w… #Alzheimers #APOE #bloodbrainbarrier #dementia
Exploration of Neuroprotective Therapy retweeted
#CoPathology
Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases
doi.org/10.1016/j.pneurobio.…
#MDSCongress @JKordower
Exploration of Neuroprotective Therapy retweeted
Want to know more about that neglected cell-type in brain, oligodendrocytes? Great recent review on oligo bioenergetics, including what happens in demyelinating diseases. doi.org/10.1111/jnc.16219
Exploration of Neuroprotective Therapy retweeted
Excited to share a new work from @kipnislab by amazing Wenqing Gao (twitter-less) on developing engineered T cell therapy for CNS injury || nature.com/articles/s41586-0…
Exploration of Neuroprotective Therapy retweeted
And another publication! Ignacio led this study, where we show that activating CB1 receptors in astrocytes shifts glycolysis toward d-serine production, crucial for synaptic and cognitive functions. Read it in @NatureComms now! nature.com/articles/s41467-0…
Exploration of Neuroprotective Therapy retweeted
Our newest pub📢: Menopausal hormone therapy (MHT) can be beneficial or not on brain health. Why? 1) length of time since menopause (too late=not as effective); 2) type of estrogens used (E1 not as effective as E2) ++. Here we 👀E1 vs E2 on neuroplasticity onlinelibrary.wiley.com/doi/…
Exploration of Neuroprotective Therapy retweeted
Microglia-specific IL-10 gene delivery inhibits neuroinflammation and neurodegeneration in a mouse model of Parkinson’s disease | Science Translational Medicine science.org/doi/10.1126/scit…
Exploration of Neuroprotective Therapy retweeted
NEW!
Flortaucipir PET uncovers relationships between tau and amyloid-β in primary age–related tauopathy and Alzheimer’s disease | Science Translational Medicine science.org/doi/10.1126/scit…
Exploration of Neuroprotective Therapy retweeted
Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism: Neuron cell.com/neuron/fulltext/S08…
Exploration of Neuroprotective Therapy retweeted
Oligodendrocytes produce amyloid-β in AD mice and reveal a threshold for plaque deposition. Great study by Andrew Sasmita, Constanze Depp et al. nature.com/articles/s41593-0…
Exploration of Neuroprotective Therapy retweeted
Engineered Brain Parasite (Toxoplasma gondii 弓形蟲) to deliver large proteins (80-110 kD) to Mouse Brain👹
A truly creative NATURE paper😎
Surely Neuron, any glia or vasculature?😁
Not impacting Lung/Spleen/Liver
How about Spinal cord or Heart?🧐
Two secretion pathways (rhoptry Toxofilin-Cre; dense granule GRA16-Cre)
Proteins delivered with retained functions: MeCP2 (Methyl-CpG binding protein); Cre
[ZFNs, Cas9 on their ways🤠◀️what determine the parasite-to-host cytosol/nuclei success?🤔]
Can we make a nonvirulent or even self-eliminating strain to digest Amyloid plaques?😆
@shaharbrr @gtesta72 @SheinerLab @AdrianoAguzzi @OdedRechavi @NatureMicrobiol 2024
nature.com/articles/s41564-0…
