The Immunotherapy Integrated Research Center accelerates discovery by promoting cross-disciplinary and cross-divisional collaboration @fredhutch.
Seattle, WA
Joined October 2019
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Immunotherapy IRC @fredhutch retweeted
Fred Hutch is recruiting an open-rank faculty member in cancer immunotherapy. Join a leading immunotherapy research community and help advance next-generation treatments from discovery to clinical translation. Apply: apply.interfolio.com/188969
Immunotherapy IRC @fredhutch retweeted
Autoantibodies cause autoimmune disease, shape infection outcomes, and alter cancer immunotherapy. But what role might they play in neuropsychiatric disease? In our new preprint, Katlyn Nemani and @JillianRJaycox take on this question in schizophrenia. 🧵
biorxiv.org/content/10.64898…
ALT https://www.biorxiv.org/content/10.64898/2026.05.04.722731v1
Immunotherapy IRC @fredhutch retweeted
T cells do the heavy lifting when it comes to the anti-tumor action of checkpoint immunotherapy. But do antibodies play a role too?
That’s the question @yile_dai looked to answer in his thesis work, out today in @Nature! 🧵below
nature.com/articles/s41586-0…
Immunotherapy IRC @fredhutch retweeted
"Huge thanks to an amazing team, mentors, and collaborators at @fredhutch @FH_IRC and globally
📄 Nature: “The ubiquitin ligase KLHL6 drives resistance to CD8⁺ T cell dysfunction”
🔗 (nature.com/articles/s41586-0…)
Immunotherapy IRC @fredhutch retweeted
Cell therapy legend Prof. Rainer Storb, recipient of the Wallace H. Coulter Award, prefacing the #ASH25 Plenary Session in front of a packed room. 🙌
@fredhutch #fanboy
Immunotherapy IRC @fredhutch retweeted
Fred Hutch at #ASH25: Dr. Danielle Kirkey & team identified CLEC2A as a cancer-specific antigen in AML — silent in normal cells, enriched in high-risk KMT2A-r AML. CLEC2A CAR T cells showed strong preclinical efficacy & head to clinical trials in 2026. #AML #CARTherapy
Immunotherapy IRC @fredhutch retweeted
Fred Hutch #BMT and #GVHD expert Dr. Geoffrey Hill (@Geoff_Hill_Lab) spoke to Fred Hutch News about the lifesaving strides that have been made in GVHD treatment, and where the research is focused next. Read more: bit.ly/48FyccO
Immunotherapy IRC @fredhutch retweeted
The world is a few steps closer to a cure for #HIV, a hopeful sign illuminated by two studies published Monday featuring work from Fred Hutch's Lillian Cohn, Daniel Reeves and others. #WorldAIDSDay bit.ly/44JxZ6X
Immunotherapy IRC @fredhutch retweeted
Fred Hutch's Immunotherapy Integrated Research Center is recruiting an Open Rank Faculty position to lead a laboratory-based program focused on tumor immunology and cancer immunotherapy with a strong vision/path toward clinical translation.
Learn more: apply.interfolio.com/176403
Immunotherapy IRC @fredhutch retweeted
6/
🧾 Takeaway:
GSI + BCMA CAR-T improves survival in BCMA-naïve RRMM, especially with low BCMA expression.
Not effective in BCMA-exposed disease. Grateful to @fredhutch co-authors @emilyliangmd, @mshadman, and others.
➡️ Prospective trials needed.
📄 astctjournal.org/article/S26…
Immunotherapy IRC @fredhutch retweeted
This month, the Big Ten Cancer Research Consortium highlights our member institution @fredhutch Cancer Center and Lawrence Fong, MD, who serves as scientific director of the Immunotherapy Integrated Research Center at Fred Hutch.
Read more: bigtencrc.org/member-feature…
Immunotherapy IRC @fredhutch retweeted
A landmark study published in @Nature by @aaronmring et al. has revealed that autoantibodies — immune proteins traditionally associated with autoimmune disease — may profoundly influence how cancer patients respond to immunotherapy. bit.ly/4o4HANS
Immunotherapy IRC @fredhutch retweeted
@mshadman at @FredHutch was honored with the #Binaytara Distinguished Faculty of the Year Award for improving #CancerCare access and education at #SCHD25. 📖Discover how Dr. Shadman enhances CAR-T access: buff.ly/sZuz5gP 🎯Join our CME/ACPE-accredited events: buff.ly/ro3NOxb #MedX #MedTwitter #MedEd #leusm #lymsm #CLLsm #hemepath #ALL #Oncology #Hematology #Nonprofit #GlobalHealth #Quote
Immunotherapy IRC @fredhutch retweeted
Big thanks to Lamar Advertising of Seattle-Tacoma for helping us light up Seattle with Obliteride spirit! Your support helps #CureCancerFaster. 💥🧡
Immunotherapy IRC @fredhutch retweeted
We are pleased to share our work evaluating some of the latest single-cell platforms, including updated chemistries, in two separate experiments using peripheral blood mononuclear cells (PBMCs). biorxiv.org/cgi/content/shor…
Immunotherapy IRC @fredhutch retweeted
Using in situ spatial transcriptomics? Try Proseg, @danielcjones’s new cell segmentation method based on probabilistic and Cellular Potts modeling. Great for @vizgen_inc Merscope, @10xGenomics Xenium, and @nanostringtech CosMx data. Preprint & code: (1/n)
doi.org/10.1101/2024.04.25.5…
Immunotherapy IRC @fredhutch retweeted
The Fred Hutch #Immunotherapy Integrated Research Center (IIRC) seeks qualified candidates for its two-year Immunotherapy Physician Scientist Program. Learn more and apply: apply.interfolio.com/121183
Immunotherapy IRC @fredhutch retweeted
Hey you. This is a wonderful opportunity to come and join us @fredhutch. Looking for people pursuing exciting areas of immunology or gene therapy as they relate to HCT. Lab-based position (ie, not looking for a physician, although Physician-scientists are of course also welcome!)
We're #hiring! Check out this great opportunity for an assistant/associate level faculty position in hemopoietic cell transplantation #HCT and/or #genetherapy at Fred Hutch: apply.interfolio.com/114766
Immunotherapy IRC @fredhutch retweeted
Fred Hutch is looking for a director of the Fred Hutch Innovation Lab (FHIL). The lab is evaluating, developing, and applying the next generation of genomics and cellular analysis technologies.
Take a look at this opportunity to join us in Seattle!
careers-fhcrc.icims.com/jobs…