@FlyFan7

pathologist

Joined June 2019
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🔬 When a T-cell lymphoma expresses CD20… think twice! An exceedingly rare case of CD20-positive primary cutaneous T-cell lymphoma, NOS, with an aggressive clinical course. The diagnostic challenge? True coexpression of CD3 and CD20—a finding that can easily raise the possibility of a B-cell lymphoma. T-cell receptor clonality and the overall clinicopathological picture were crucial in establishing the diagnosis. A striking reminder that aberrant immunophenotypes can challenge even our most familiar diagnostic algorithms. Read the full paper by Danielle R Rinck, Michael S Chang, Christopher Iriarte, and Robert Willim Link here bit.ly/4zWfZV7
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New in #HumPathol: BAP1 Loss and TFE3 Immunoexpression in High-Grade Clear Cell Renal Cell Carcinoma. sciencedirect.com/science/ar… #pathology #PathTwitter #PathX #GUpath
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A 70 Yr 👵 A Huge left ovarian mass. ➻ Thoughts ? #PathTwitter #FGT #Pathology #pathx – at Ethiopia
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Finally, a histologic biomarker for USP6-associated tumors, led by Margarita Muñoz de Toro @StanfordPath: pubmed.ncbi.nlm.nih.gov/4285… A new technique also highlighted in the excellent recent work by Dinh et al: pubmed.ncbi.nlm.nih.gov/4250… #BSTpath
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Tumors of the Breast, WHO 6th edition update: A high-grade or HER2-positive carcinoma with mucin should be called invasive ductal carcinoma/NST with mucin production/secretion Avoid “IDC with mucinous features.” Colleagues may interpret that as pure mucinous carcinoma, which this is not. Dr. Allison. 2026 Diagnostic Pathology Update #USCAP #pathology #pathX
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Parotid Oncocytomas Express the Glycoprotein Non-metastatic Melanoma Protein B (GPNMB): A Potential Link with Birt-Hogg-Dubé Syndrome A Peraza-Labrador, J Bishop, LS Schmidt, et al rdcu.be/FdAnLhUNSfLa #HeadNeckPathol #HNPJ #HeadandNeckPath #Pathology #ENTPath #PathologyTweet
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🎃 WTR Case Series | October 🔬 Case 11: Thyroblastoma, NOS • Primitive thyroid follicles • SALL4+ primitive cells • Immature neural elements • Focal mature bone & squamous nests 🧬 TTF1+ • PAX8+ • SALL4+ • Synaptophysin+ • TP53+ 👉 admin.worldtumorregistry.org… #Pathology
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fanbotao retweeted
Bin Xu@BinXu168 Jun 2017
Replying to @BinXu16 @kriyer68 @smlungpathguy @VijayPatho @sam_albadri @DraEosina @ENTpathology @marenwhymd @GeronimoJrLapac @Histopatolomon @Helena_Path @DrjohninNE @lara_pijuan @NRiddleMD @pathowitter
👍to all who get the diagnosis in no time. PTC Cribriform morular variant, with prominent supra & subnuclear vacuoles. #ENTpath #thyroid
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Happy to share that our study is now published in Human Pathology! We found that TFE3 expression is significantly more frequent in BAP1-deficient clear cell RCCs, potentially creating a diagnostic pitfall, particularly in limited biopsy specimens. sciencedirect.com/science/ar…
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Kidney can also have lots of different tumors. Female, 45yo with a metanephric adenoma!. Stains are PAX8 and WT1
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Epithelioid mesothelioma in the peritoneum: • Can look morphologically similar to serous borderline tumor (pic 1) • Can show calcifications similar to low-grade serous carcinoma (pic 2) Warning: PAX8 and SOX17 are not reliable in this differential, they can be positive in up to ~15% of peritoneal mesotheliomas Helpful stains: ER and PR are almost always negative in mesotheliomas An ER/PR-positive proliferation is unlikely to be a mesothelioma Dr. Chapel. Peritoneal Mesothelial Pathology #ISGyP #pathology #PathX
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🔬 Folliculin mutated renal tumor: H&E & GPNMB IHC Want to sharpen your GU pathology expertise? Join Johns Hopkins faculty for Contemporary Issues in GU Pathology: What Every Pathologist Should Know, Feb 5–7, 2027. Online CME/MOC with updates on WHO classifications.
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Today's case. Not too hard, but fun. Appendix mass. #pathology #gipath
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Histopathological patterns for the specific diagnosis of lymphadenopathies (LADs), illustrating architectural alterations in lymph node compartments. 🔬 mdpi.com/2673-6357/5/3/26
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Bone. What is your diagnosis?🔎 Poll below 🗳️👇 #PathPuzzle 🕵️‍♂️ @UMichPath #Pathology #PathX #PathTwitter
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One look at this intraoperative smear prep and you can diagnose this brain tumor. #pathology #neuropath #pathtwitter
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Direct tumour–adipocyte contact/Stroma AReactive Invasion Front Area (TAC/SARIFA) predicts adverse outcome in colorectal cancer: a focused evidence synthesis and meta‐analysis #GIpath pmc.ncbi.nlm.nih.gov/article…
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Read the article "Periocular Endocrine Mucin-Producing Sweat Gland Carcinoma and Mucinous Carcinoma—An Institutional Series Including 49 Patients" by Dr. Stone et al. Link to read: mdpi.com/2296-3529/13/4/48
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#DiagnoseThis! The patient is a 67 y/o Caucasian female with slowly progressive kidney disease and 2.3 gm/24 hr proteinuria. Aside from hypertension she has no significant past medical history. Congo red was negative, however immunofluorescence showed IgG and lambda staining within glomeruli. What is this immunoperoxidase stain? For bonus points, what was found on electron microscopy? #renalpath #kidneypath #pathology #renal
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Tumor-to-tumor metastasis! Invasive ductal breast carcinoma metastatic to a meningioma: a fascinating example of one tumor finding its way to another. #PathTwitter #MedTwitter #BreastPath #NeuroPath #PathResident
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