Research Scientist @ CRCT-IUCT Toulouse | T lymphocytes, RNP granules, immune checkpoints, small molecule drug discovery.
Toulouse
Joined May 2022
- Tweets86
- Following318
- Followers83
- Likes548
Don-Marc Franchini retweeted
P-bodies; sites of excess RNA accumulation, or actors in gene regulation? We tackle this long-held question by looking at the RNA content in p-bodies across the cell cycle. Feedback much appreciated.
authors.elsevier.com/c/1jtTs…
Don-Marc Franchini retweeted
Please RT.
Are you interested in performing your master thesis with us @imbmainz? We have exciting projects on nuclear myosin VI in genome stability. Details below
imb.de/fileadmin/imb/PDO_Web…
If interested please apply via the link or contact me directly.
Don-Marc Franchini retweeted
Excited to see our story showing that the #stressresponse regulator #HSF1 modulates NK cell anti-tumour immunity out in @NatureCellBio. Thanks to fantastic work with @nkourtis @iannisaifantis1 and team @nyulangone 🧵👇 nature.com/articles/s41556-0…
Don-Marc Franchini retweeted
1/Excited to share our latest study showing that RNA sequestration in P-bodies sustains myeloid leukemia - now out in @NatureCellBio! nature.com/articles/s41556-0…. 🧵 below:
Don-Marc Franchini retweeted
I am very proud of the superstar postdoc @Yang_Haojun_01, who discovered how to translation control underlying fasting and ketogenic diet in health and cancer.
nature.com/articles/s41586-0…
Don-Marc Franchini retweeted
Excited to announce our latest publication from the amazing Ying Xie in @MolecularCell
We find that stress granules and P-bodies fluidize the cytoplasm in response to diverse stresses. Tweetorial soon!
cell.com/molecular-cell/abst…
Don-Marc Franchini retweeted
@Xisca_Aguilo and me have curated a collection on translational regulation and #cancer, out now in @NAR_Cancer_EIC
🔗academic.oup.com/narcancer/p…
Contributions from @LorenzoMontana4 @s_millevoi @GebauerLab @johnprensner @Denicourt_Lab @Sblancolab @FallerLab and others
#RNA #RBP
Don-Marc Franchini retweeted
If you are interested in NK cells and cancer immunotherapy, two positions are open in @EricVivier1's lab at @CIML_Immunology. For more info 👇
Don-Marc Franchini retweeted
I am recruiting a talented and dedicated postdoc!
tRNA epitranscriptomics-immunoOncology
Please apply @ [email protected]
giga.uliege.be/upload/docs/a…
@Translacore @EACRnews @epitran @TSI_lab_LIH @ArnBlomme
Don-Marc Franchini retweeted
Delighted to share our article on the Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders published @iScience_CP. Thanks to the authors @AnaisCornebois @MarieSorbara @Margot_Cristol @CordelierPierre and our collaborators from @sanofi!
cell.com/iscience/fulltext/S…
Don-Marc Franchini retweeted
Our recent work (led by @sammykeyport) on evolution of biomolecular condensation is now highlighted as a featured article (and is open access) 🔬 nature.com/collections/bbcae… nature.com/articles/s41467-0…
Don-Marc Franchini retweeted
🚨Postdoc position announcement!!! Please share and RT.🚨
The Scipioni Lab is seeking a highly motivated and skilled postdoctoral researcher to work on cutting-edge projects involving the design, development, and implementation of advanced microscopes (see below) 1/4
Don-Marc Franchini retweeted
Online Now: Time-resolved profiling of RNA binding proteins throughout the mRNA life cycle dlvr.it/T5GfWv
Don-Marc Franchini retweeted
Finally, out!
DDX6 modulates P-body and stress granule assembly, composition, and docking: doi.org/10.1083/jcb.20230602…
We show that the P-body protein and RNA helicase DDX6 regulates stress granules by limiting RNA and RNA binding protein partitioning.
Don-Marc Franchini retweeted
Make sure not to miss this workshop on RNA and cancer research organized by students together with @FabienneMEGGET2 of the RNA focus research axis of the @crctoncopole. Great science is guaranteed!
Curious about #RNA & #cancer research? Don't miss the 𝟐𝐧𝐝 𝐑𝐍𝐀&𝐜𝐚𝐧𝐜𝐞𝐫 𝐰𝐨𝐫𝐤𝐬𝐡𝐨𝐩 at the Cancer Research Center of Toulouse on May 23. Present your research next to international keynote speakers and industry sponsors. Submit here: rnacancer.sciencesconf.org.
Don-Marc Franchini retweeted
Very excited to share our paper out today in @naturemethods, introducing TREX (Targeted RNase H-mediated Extraction of X-linked RBPs), a novel approach to reveal proteins that bind to any region of any RNA molecule of interest in living cells🧪: rdcu.be/dyZ2c (1/10)
Don-Marc Franchini retweeted
Stress response silencing by an E3 ligase mutated in neurodegeneration nature.com/articles/s41586-0…
Don-Marc Franchini retweeted
Pleased to share our Opinion published in @TrendsBiochem! We propose that 'mRNA accessibility' within mRNPs is an important determinant of gene expression, based on recent studies by us and others that dovetail nicely to support this concept.
authors.elsevier.com/c/1iDe1…