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Our laboratory investigates molecular pathways that sculpt the connectivity of circuits, alter their performance, and shape behavior. @UmassMedical

Worcester, MA
Joined September 2019
Photo by Michael Francis Lab (@FrancisLab4)Photo by Michael Francis Lab (@FrancisLab4)Photo by Michael Francis Lab (@FrancisLab4)Photo by Michael Francis Lab (@FrancisLab4)Photo by Michael Francis Lab (@FrancisLab4)Photo by Michael Francis Lab (@FrancisLab4)Photo by Michael Francis Lab (@FrancisLab4)Photo by Michael Francis Lab (@FrancisLab4)Photo by Michael Francis Lab (@FrancisLab4)Photo by Michael Francis Lab (@FrancisLab4)
Michael Francis Lab retweeted
Presented a short and simple adaptation of my thesis, in 3 min with only one slide. 3MT finalist. UMass Chan Medical School
Well done @KasturiBiswas9 on a fantastic #3minutethesis presentation! Stress Wars: Neurons Strike Back
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Michael Francis Lab retweeted
Our lab’s new publication in @NatureComms by Jacob Stillmam @NeurobioUMass @UMassChan @UMassChanGSBS and Francisco Mendes Lopes. A great joint effort to show how lipofuscin-like autofluorescence can confound microglial engulfment analyses. nature.com/articles/s41467-0…
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Michael Francis Lab retweeted
🔬 The Francis Lab (@FrancisLab4) at @UMassChan defines an unappreciated role for DVE-1 in directing #synapse elimination during circuit remodeling, likely through transcriptional regulation of protein degradation processes. @NatureComms | bit.ly/3RhmI7T
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Come to the @UMassChan @UMassChanGSBS booth #56 @SfNtweets
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Started Day 2 at #SfN23 with a talk from Ailsa from the Lodato Lab @UMassChan @UMassChanGSBS
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Michael Francis Lab retweeted
Finally out! Check our new resource of neuropeptide-GPCR interactions in C. elegans. We identify 461 peptide-GPCR pairs that allow mapping peptidergic circuits. See also this application on the worm's peptide connectome doi.org/10.1101/2022.10.30.5… Resource: doi.org/10.1101/2022.10.30.5… 🧵
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Michael Francis Lab retweeted
4️⃣Several of these in vitro interactions were validated in vivo through our network of excellent collaborators (including @domiglauser @betenoire1 @WpiJagan @FrancisLab4 @wormychew @LabSchafer), characterizing novel roles of neuropeptides in animal behavior and physiology.
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Michael Francis Lab retweeted
Resubmission to different journals xitter.gq/_figensezgin/status/15…
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Michael Francis Lab retweeted
Congratulations 💐 to Dr. Monika Chitre for defending her thesis. We are very proud! @NeurobioUMass , @UMassChan
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Chair of the Neurobiology Department, Vivian Budnik, PhD, received the 2022 Outstanding Mentoring to Women Faculty Award at the 22nd annual Women’s Faculty Awards! #UMassChan umassmed.edu/news/news-archi…
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Congratulations to my chair, mentor, friend, and scientific hero Dr. Vivian Budnik for the @UMassChan @UMassNeuro Chancellors Award for Excellence in Mentoring. You are a guiding light.
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Michael Francis Lab retweeted
How do #synapses form and maintain their architecture? Oliver et al describe a mechanism for stabilizing mature circuit connectivity through adhesion by the presynaptic protein neurexin in #Celegans 🔎: doi.org/10.1371/journal.pgen… @devblair3 @alison_marie1 @FrancisLab4 #neurons
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Michael Francis Lab retweeted
Looking to hire at least 2 motivated Research associates. Feel free to contact me directly via email. You can find me at schaferlabumms.com
Michael Francis Lab retweeted
We’re in Wormtown Brewery with @akwalker_lab and @FrancisLab4!
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Michael Francis Lab retweeted
Editor going over the manuscripts submitted just before Christmas
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On his last week leading #nih - #TBT to @NIHDirector's 2019 visit to @UMassChan with @RepMcGovern. A grateful medical research community salutes your service and leadership! #whyumasschan @UMassChanGSBS #ThankYouDrCollins
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Michael Francis Lab retweeted
Join us at the next virtual public @UMassMedPostDoc Science Cafe and hear about out research! @sramac2 @FrancisLab4 and @s_werneburg @SchaferLabUMCMS @UMassChan
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Michael Francis Lab retweeted
Former labmate @NavonilBanerjee gives an amazing talk at #Worm21 ! Distinct interneurons can establish similar behaviors across life stages. Beautiful imaging data. Congrats Navonil!
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Michael Francis Lab retweeted
Very happy to share this tweet from @JCellBiol . 6 years of work by graduate student Dharmendra (not in twitter), great team work by @keerthanaponba1, @swagatad86, Kasturi (MSc student of NBRC/now at UMASS) and @basu_atrayee. Great support from @DBT_NBRC, @India_Alliance
Work from Dharmendra Puri et al. @GhoshRoyLab @DBT_NBRC shows that the #Kinesin-13 family #microtubule depolymerizing factor KLP-7 is important for the establishment of microtubule polarity in neurons. bit.ly/3xkXIj8 Supported by @DBTIndia @India_Alliance
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UMASS Medical School is hosting a new Voices in Science (ViS) seminar series organized by students, postdocs, and faculty! The ViS seminar series will highlight scientific successes of scientists from diverse backgrounds. Dr. Woappi is our first ViS speaker! DM me for zoom link