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The Stem Cell and Leukemia Lab @Lund_Stem @lunduniversity. Focus on normal- and malignant hemtopoietic stem cells and single-cell genomics.

Lund, Sweden
Joined May 2020
Photo by KarlssonLab@LU (@GKarlssonLab)Photo by KarlssonLab@LU (@GKarlssonLab)Photo by KarlssonLab@LU (@GKarlssonLab)Photo by KarlssonLab@LU (@GKarlssonLab)Photo by KarlssonLab@LU (@GKarlssonLab)Photo by KarlssonLab@LU (@GKarlssonLab)Photo by KarlssonLab@LU (@GKarlssonLab)Photo by KarlssonLab@LU (@GKarlssonLab)Photo by KarlssonLab@LU (@GKarlssonLab)Photo by KarlssonLab@LU (@GKarlssonLab)
#MyOAarticle "Scarf enables a highly memory-efficient analysis of large-scale single-cell genomics data" received 5,567 downloads since its publication! Access the article here tinyurl.com/38hkfhxj
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Congratulations to Fatemeh Mojgan Safi for brilliantly defending her thesis on HSC lineage priming and CD9 @Lund_Stem! Great discussion with opponent Kim Theilgaard-Mönch. #science #research #PhD #thesisdefense #LundStemCellCenter
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Presenting at the fantastic Danish single-cell meeting
Systematically mapping enhancers in hematopoietic stem and progenitor cells👍 Göran Karlsson @GKarlssonLab Lund University @lunduniversity @Lund_Stem #singlecellCPH23 biorxiv.org/content/10.1101/…
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The lab is very proud of Dr Parashar Dhapola who brilliantly defended his thesis today. Thanks to Kostya Khodosevich @KhodosevichLab for being an excellent faculty opponent! Congrats @ParasharDhapola!
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The latest work from our lab by @ParasharDhapola and colleagues!Scarf is a memory efficient tool for single-cell genomic analysis with important applications. nature.com/articles/s41467-0…
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So proud of Mikael Sommarin for receiving his PhD yesterday! 🍾🎓Thanks David Kent @scienceadvocacy for a brilliant discussion!
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Minireview from our lab and our friends in @BoiersLab on the power of single-cell heterogeneity analysis for understanding developmental hematopoiesis. frontiersin.org/article/10.3…
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1/7 We are delighted to introduce Scarf, a single-cell analysis toolkit that puts atlas-scale datasets within the reach of all scientists, requiring just a laptop. One can process scRNA-Seq data of 4 million cells using less than 16GB of RAM. Preprint: doi.org/10.1101/2021.05.02.4…
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2/7 Scarf allows the analysis of the largest existing datasets – including single-cell RNA and ATAC-Seq – with high memory efficiency and low computation time.
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Single-Cell Multiomics Reveals Distinct Cell States at the Top of Human Hematopoietic Hierarchy disq.us/t/3vyf410 Latest work from our lab!
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Single‐cell sequencing in translational cancer research and challenges to meet clinical diagnostic needs onlinelibrary.wiley.com/doi/…
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:)
Congratulations to Göran Karlsson on being awarded the prestigious Wallenberg Acadamy Fellow prolongation grant! #cancer #stemcells #leukemia @StemCellsandLe1 @KAWstiftelsen @medfak_LU @Lundsuni kaw.wallenberg.org/en/resear…
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Our PhD students continue to impress! Today Rebecca Warfvinge elegantly presented our perhaps most advanced single-cell project involving multi-omic analysis of rare patient material from two clinical trials.
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An audience of 80 listened as our talented PhD student Parashar Dhapola @parashar_tweets delivered a fantastic educational seminar in how he analyses single-cell genomic data in hematology. Several of his tools and method should be published in the summer/autumn so stay tuned!
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Nice blog from our friends in the Yuan lab! Remedy for the covid-19 crisis is to get important work done before 7 am. We are all doomed :).
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Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction disq.us/t/3obvzkg Latest work from the lab! :)
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