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Gopinath Lab (@GopinathLab) profile picture

Gopinath Lab

@GopinathLab

We study the vaginal microbiome and mucosal immunology @HarvardChanSPH! PI @SmitaGopinath. Account run by lab members.

 Boston, MA
Joined August 2021
  • Tweets21
  • Following43
  • Followers70
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Photo by Gopinath Lab (@GopinathLab)Photo by Gopinath Lab (@GopinathLab)Photo by Gopinath Lab (@GopinathLab)Photo by Gopinath Lab (@GopinathLab)
Gopinath Lab retweeted
Devlin Lab (@DevlinLab) profile picture
Devlin Lab@DevlinLab18 Sep 2023
Please share! The Devlin lab is looking for postdoc fellows. Candidates with experience in either 1) tissue culture & cell-based assay development or 2) analytical chemistry, biochem, or organic chem. are encouraged to visit our lab website & email Prof. Devlin directly. (1/2)
Image from Devlin Lab (@DevlinLab)
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That’s our very own @AndaAdams 🤩
IDSOG (@idsog_org) profile pictureIDSOG@idsog_org28 Jul 2023
3 captivating oral abstracts are being shared during this session! Check them out from 10:30-11:15 AM. #IDSOG50
Image from IDSOG (@idsog_org)
Image from IDSOG (@idsog_org)
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Catch @AndaAdams at IDSOG session 4 where she will be presenting her work on bacterial cell walls inhibiting herpesvirus infection!#IDSOG50
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Congrats Nora on finishing the summer internship and learning how to transform finicky lactobacilli!
Image from Gopinath Lab (@GopinathLab)
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Check out our review about the role of microbiota in cancer initiation, promotion, and progression! Congrats to @JenTekle for a wonderful job! 🥳 nature.com/articles/s41568-0…
Bacteria in cancer initiation, promotion and progression

Bacteria in cancer initiation, promotion and progression

Nature Reviews Cancer - The role of the microbiota in tumorigenesis has garnered considerable attention over the past two decades. In this Review, El Tekle and Garrett explore the current and...

nature.com
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Birthday cake and science nails! Happy birthday Gin and Maryam🥳
Image from Gopinath Lab (@GopinathLab)
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We are hiring a postdoc/PhD student to investigate the mechanism of differentiation of T cells and dendritic cells. Details can be found in the link below. Our lab is located about 30 min from New York City. Pls RT. JREC-IN Portal : Postdoc in immunology jrecin.jst.go.jp/seek/SeekJo…
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Do you have #recurrentBV? Have antibiotics failed over and over? Live in the Boston area? Check out our clinical research study of vaginal microbiome transplant #VMT motifstudy.org @kwonlab
Image from Caroline Mitchell (@bostonvaginadoc)
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Congrats @AndaAdams🤩!
hutlab (@hutlab) profile picturehutlab@hutlab17 May 2023
Thank you to everyone for an amazing @HCMPHmicrobiome Symposium, including but definitely not limited to all speakers, our keynotes @bushmanlab, Joeseph Petrosino, and @kyrpides, and a big congratulations to @AndaAdams and @ManderzzG for strong posters, winning our poster awards!
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Gopinath Lab retweeted
hutlab (@hutlab) profile picture
hutlab@hutlab11 May 2023
It's almost time for the annual HCMPH Symposium! We've reached capacity in person, but we'd love to welcome more attendees virtually. Register for free thanks to sponsorship from Corundum Systems Biology, Seres Therapeutics, PacBio, and others at hcmph.sph.harvard.edu/hcmph-…
Image from hutlab (@hutlab)
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Be a vagina superhero! Pre-menopausal people in/near Boston who have never had BV and want to donate vaginal fluid to improve #BVtreatment - contact us! motifstudy.org @kwonlab @SmitaGopinath @MGHVCRBResearch
Image from Caroline Mitchell (@bostonvaginadoc)
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Excited to see @RuthFranklinLab’s talk today!
Harvard Immunology and Infectious Diseases Dept (@HarvardIID) profile pictureHarvard Immunology and Infectious Diseases Dept@HarvardIID10 May 2023
Join us today, May 10th, from 11:30 a.m. - 12:30 p.m. for a special seminar presentation by Ruth Franklin, PhD: Macrophages regulate inflammatory responses following viral respiratory infection. For more event information, visit this link: loom.ly/wmP-Rj4
Image from Harvard Immunology and Infectious Diseases Dept (@HarvardIID)
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Officially a PhD candidate🤩! Congrats to Gin on passing her PQE with flying colours!!
Image from Gopinath Lab (@GopinathLab)
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Gin is now an #NSFGRFP fellow!! Congratulations on a fantastic proposal investigating microbial responses to menstruation! ⭐️🩸
Image from Gopinath Lab (@GopinathLab)
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Replying to @AndaAdams
@AndaAdams presents her work on how inter-microbial ineractions affect vaginal viral infections at MEWG today!
hutlab (@hutlab) profile picturehutlab@hutlab13 Feb 2023
We hope to see you at MEWG today, where Amanda Adams from @SmitaGopinath's Lab will be presenting her work studying interactions between bacteria and virus in the vaginal microbiome!
Image from hutlab (@hutlab)
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Gopinath Lab retweeted
mSphere (@mSphereJ) profile picture
mSphere@mSphereJ11 Jan 2023
Vaginal lactobacilli metabolically contribute in species-specific manner to cervicovaginal homeostasis. Lactobacilli altered metabolites related to amino acid metabolism such as N-acetyl amino acids & aromatic lactic acids @ScientistNicole @HerbstKralovetz journals.asm.org/doi/10.1128…
L. mulieris JV-V16, L. iners AB-107, and L. paragasseri JV-V03 colonize 3D human CEC models. Pseudocolored SEM images of L. mulieris JV-V16 (blue), L. iners AB-107 (yellow), and L. paragasseri JV-V03 (red) demonstrate colonization of 3D CECs. SEM images were captured at 3,500× (top) or 10,000× (bottom) magnification. All vaginal Lactobacillus strains exhibited a bacillus or rod-shaped morphology and colonized 3D CECs in aggregates. CECs colonized by L. iners AB-107 showed signs of cell stress. Arrows indicate extracellular material and bacterial cells that were regularly observed in the lactobacilli autoaggregates.

ALT L. mulieris JV-V16, L. iners AB-107, and L. paragasseri JV-V03 colonize 3D human CEC models. Pseudocolored SEM images of L. mulieris JV-V16 (blue), L. iners AB-107 (yellow), and L. paragasseri JV-V03 (red) demonstrate colonization of 3D CECs. SEM images were captured at 3,500× (top) or 10,000× (bottom) magnification. All vaginal Lactobacillus strains exhibited a bacillus or rod-shaped morphology and colonized 3D CECs in aggregates. CECs colonized by L. iners AB-107 showed signs of cell stress. Arrows indicate extracellular material and bacterial cells that were regularly observed in the lactobacilli autoaggregates.

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When your science and baked goods meet! Thank you for a beautiful cake @ceciliawebber_ 🤩😋
Image from Smita Gopinath (@SmitaGopinath)
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Replying to @AndaAdams
@AndaAdams presenting our lab's work on bacterial-viral interactions in the vaginal mucosa today in #kshumanmicro22 - Amanda won a travel fellowship for her work and has been bringing some much needed glycobiology wisdom to our mucosal immunology lab!
Amanda Adams (@AndaAdams) profile pictureAmanda Adams@AndaAdams5 Dec 2022
Keystone symposia on the ecology and evolution of the microbiome is off to a great start! Can’t wait to present some of our work from @GopinathLab @HarvardIID #kshumanmicro22 check out this Banff hotel view 😍
Image from Amanda Adams (@AndaAdams)
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For those of you at #kshumanmicro22, be sure to check out @AndaAdams’ Tuesday morning talk about how the vaginal microbiome influences viral infection!!
Amanda Adams (@AndaAdams) profile pictureAmanda Adams@AndaAdams5 Dec 2022
Keystone symposia on the ecology and evolution of the microbiome is off to a great start! Can’t wait to present some of our work from @GopinathLab @HarvardIID #kshumanmicro22 check out this Banff hotel view 😍
Image from Amanda Adams (@AndaAdams)
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