Preclinical and clinical research groups at the intersection of addiction, stress, and affect led by Markus Heilig. Part of @CSAN_LiU at @liu_universitet
Linköping, Sverige
Joined March 2018
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Heilig Lab retweeted
Dr. Markus Heilig kicked off day 2 of the biennial workshop with an engaging talk on deconstructing and reverse-translating alcohol addiction to uncover molecular targets for treatment.
Heilig Lab retweeted
#TWiNPP
Lofberg et al. evaluate the neurobiological cravings signature (NCS), an fMRI-based machine learning marker, as a predictor of outcomes in alcohol use disorder🧠 / @NeuroIP @Heilig_Lab @CSAN_LiU
nature.com/articles/s41386-0…
Heilig Lab retweeted
#ThisWeekInNPP
Studies in animal models & healthy humans suggested that increasing the eCB ligand AEA (via FAAH inhibition) may be a novel PTSD treatment - but did it work? Find out in this recent paper from @MayoOnTheBrain @canna_brain @Heilig_Lab & co
nature.com/articles/s41386-0…
Heilig Lab retweeted
A huge thank you to all of our speakers and attendees for making "The Intersection of Stress and Addiction" such a success!
Heilig Lab retweeted
Our final keynote speaker, Dr. Markus Heilig @Heilig_Lab, delivered a thought-provoking talk on “Deconstructing alcohol addiction in search of druggable molecular mechanisms”!
Heilig Lab retweeted
Why do some heavy drinkers keep choosing alcohol over other rewards, even when it costs them? An interesting paper from the @Heilig_Lab looks into how drinking severity influences choice when alcohol competes with natural reward.
Heilig Lab retweeted
#JNeurosci: Toivainen, Petrella et al. generated and characterized a novel PKCδ-Cre knock-in rat model that offers novel opportunities for functional studies of PKCδ-expressing neurons in behaviors relevant to human conditions. @liu_universitet
jneurosci.org/lookup/DOI/10.…
Heilig Lab retweeted
Time for another CSAN seminar! Today Wolfgang Sommer @UniHeidelberg gave a very nice translational overview on the concepts of #habit and #compulsion in #AUD.
Heilig Lab retweeted
Visit of the week: I visited @CSAN_LiU & @Heilig_Lab. The quality of their research spanning from molecular biology to clinical trials is truly remarkable. I highlight one of the center's excellent papers on ghrelin effects on delay discounting in humans
pubmed.ncbi.nlm.nih.gov/3704…
Heilig Lab retweeted
Congratulations to @Lorenzo__Leggio for being appointed as the NIDA IRP Clinical Director 🎊
We are lucky to have you, Sir 🤓✨️
@NIDAnews @IRPatNIH
Heilig Lab retweeted
Fabulous review on heroin and its metabolites by Aldo Badiani and colleagues
👉Heroin users do not take a single drug but a combo of four drugs: heroin > 6-MAM > morphine > M6G
This might explain why heroin remains the most abused opioid world-wide
1/N
nature.com/articles/s41398-0…
Heilig Lab retweeted
The role of Ghrelin in value-based decision making. It took 10 years with many twists and turns but now it is finally out. I feel a little bit like I can retire now jci.org/articles/view/168260…
Heilig Lab retweeted
SO EXCITED this paper is finally out! @NeuroIP & I (+ many @CSAN_LiU colleagues) spent the past 5+ yrs exploring what mechanisms may render individuals resilient to SUD development after childhood maltreatment
Spoiler alert: the answer is the endocannabinoid system (as always)
Childhood maltreatment is a risk factor for #SUD later in life. What makes some people #resilient to developing #SUD? We show the mechanisms that might be behind it. Another fun and heroic @CSAN_LiU effort, with glorious partner in crime @MayoOnTheBrain rdcu.be/c9LAE
Heilig Lab retweeted
Childhood maltreatment is a risk factor for #SUD later in life. What makes some people #resilient to developing #SUD? We show the mechanisms that might be behind it. Another fun and heroic @CSAN_LiU effort, with glorious partner in crime @MayoOnTheBrain rdcu.be/c9LAE
Heilig Lab retweeted
Att den illegala narkotikamarknaden stryps vid en legalisering av droger är feltänkt. Det visar flera studier, kommenterar LiU-forskare Markus Heilig en uppmärksammad video från CUF Storstockholm. @Heilig_Lab tv4.se/artikel/2FWeV57cA5Zvy…
Heilig Lab retweeted
New in @npp_journal: Activation of GABAB receptors in central amygdala attenuates activity of PKCδ + neurons and suppresses punishment-resistant alcohol self-administration in rats @EsiDomi @Heilig_Lab
nature.com/articles/s41386-0…
Heilig Lab retweeted
Faktaresistens med potential att döda – professorn i psykiatri Markus Heilig skriver ett engagerat försvar för de ifrågasatta depressionsläkemedlen (SSRI) och menar att vi i Sverige kan känna oss trygga med hur depressioner behandlas.
kvartal.se/artiklar/faktares…
Heilig Lab retweeted
Finns det något speciellt i hjärnan hos den som är villig att donera organ? @AndersHansen74 besöker LiU:s Campus US för att få svar i Din hjärna - ond eller god. @LiU_CMIV @CSAN_LiU @NeuroIP svtplay.se/video/KLD9nX5/din…
Heilig Lab retweeted
🚨🚨PAPER ALERT🚨🚨
We're glad to share with you our laboratory's first paper published in @npp_journal about alcohol and social choice in Wistar rats (full text: nature.com/articles/s41386-0…).
We also have a🧵for you!
Heilig Lab retweeted
Låga nivåer av ett protein i hjärnan kan göra vissa mer utsatta för #ångest och posttraumatiskt stressyndrom (#PTSD). Det visar en studie från LiU.
@Heilig_Lab @CSAN_LiU tidningenhalsa.se/artiklar/h…