Multidisciplinary research on the contribution of genes, epigenetics, physiology and environment to Substance Use Disorders. Innovative treatment developments.

Joined November 2018
Congratulations Jacquie on your Assistant Professor position and new lab at Mount Sinai! @jmferland
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Come join the Hurd lab on Nov. 13th to attend Tanni Rahman's dissertation defense! @tanni_rahman @SinaiBrain @neurovoice
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Dr. Hurd will be making a presentation at the Consulate General of Italy this Wednesday evening!
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Mark your calendars for October 11th! Yasmin Hurd @neurovoice will be the keynote speaker!
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It was great working with the interns this summer in the Hurd lab! If you would like to attend next summer, apply here labs.neuroscience.mssm.edu/i…
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Great Hurd team representation at the FBI Retreat. Wonderful job all around!!
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Congratulations Randy Ellis PhD graduate. You are a champion! @randalljellis
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Congratulations to Yasmin Hurd for being inducted into the National Academy of Sciences!
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Dr. Hurd will be answering your questions tonight during the premiere of this @NOVAeducation program on the clinical potential of psychedelics at 9pm ET. Watch it here: youtube.com/watch?v=bhFxZovI…
Discover how psychedelics are unlocking new ways to treat conditions like addiction and depression. "Can Psychedelics Cure?" premieres tonight, WED OCT 19 at 9/8c on @PBS. to.pbs.org/3yI6jiY
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Postdoc @bara_anissa presenting at #WCBR2022 on the effects of prenatal #cannabis exposure on developmental reprogramming in the placenta! @MountSinaiPsych @winter_brain
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Finally, STRING PPIs identified other epigenetic regulators in the Kmt2a complex that were altered in our datasets, emphasizing the profound effects of PTE on epigenetic regulation.
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Next, we used CRISPR to upregulate Kmt2a in neural progenitor cells, and RNA-seq showed perturbations *again* to synaptic plasticity-related genes, and gene-gene correlations similar to our in vivo data!
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Conducting ChIP-seq with H3K4me3 (Kmt2a target) in the NAc revealed a surprising overlap of genes with H3K4me3 enrichment and *reduced* mRNA expression!
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We conducted RNA-seq to elucidate the effects of PTE on the NAc transcriptome and identified overlapping DEGs between DESeq2 and limma related to synaptic and neuronal functioning.
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