🎙️#JAMAAIConversations: In this episode, host Roy Perlis, MD, MSc, and Kevin Roose discussed how rapid change in #ArtificialIntelligence complicates reporting, research, and clinical adoption. The conversation examines how clinicians and health systems may need to assess new AI tools as their capabilities evolve from week to week. 🎧 Listen now: ja.ma/3W2JiFU

In a #PieceofMyMind, a physician describes how long-term hospitalization blurs the boundaries between parent, clinician, guest, and caregiver. ja.ma/4iakqTX

🎙️#HealthyDialogue: In this episode, host Derek Angus, MD, MPH, and Nancy Davidson, MD, discussed how #BreastCancer has become increasingly manageable as treatment has become more tailored to #tumor biology. The discussion describes how biologically targeted therapies have expanded options for luminal and ERBB2-positive #disease while unmet needs remain in triple-negative disease, prevention, and reducing adverse effects. 🎧 Listen now: ja.ma/4yzH8uW

Compounded #GlucagonLikePeptide1 receptor agonists used for #WeightLoss increased rapidly in Nebraska prescription monitoring data beginning in 2024 and were dispensed entirely by out-of-state pharmacies. Most were self-paid, which indicates that claims-based surveillance may miss a large share of this market and supports the need for pharmacovigilance infrastructure that tracks compounded products separately from US Food and Drug Administration approved products. ja.ma/4shW9Ac

💬 Viewpoint by Sunjay Letchuman, MD, and @SenBillCassidy, MD: Recent actions by the Centers for Medicare & Medicaid Services include the Version 28 risk adjustment model, exclusion of diagnoses from unlinked medical record reviews and audio-only telehealth encounters beginning in 2027, and stronger Risk Adjustment Data Validation audits. Further reform of #MedicareAdvantage payment policy could help limit coding-related overpayments and slow added pressure on federal spending and the Medicare Hospital Insurance Trust Fund. ja.ma/4hXFpdX

#MedNews: ✈️ Pilots and flight attendants may have a higher risk of death from radiation-related cancers than all other professions, a recent study suggests. Learn more about in-flight radiation exposure and what could help address the risk. ja.ma/3WzfOQ6

#MedNews: Updated clinical guidance from the American College of Obstetricians & Gynecologists supports the removal of both fallopian tubes during certain previously scheduled surgeries, reflecting growing evidence that it can help reduce ovarian cancer in average-risk women. Here's what to know about opportunistic bilateral salpingectomy. ja.ma/4yzJkmn

💬 Perspective by Nikhil Sahni, MBA, MPA/ID, Merjan Ozisik, MBE, David Cutler, PhD, and @ZekeEmanuel, MD, PhD: US #HealthCare spending growth slowed from 2009 to 2019, but recent increases have renewed uncertainty about future spending as a share of gross domestic product. Potential moderating forces include wider #AI adoption, site-neutral payments, slower price growth for specific drugs, expansion of value-based specialty care, reduced Medicare Advantage risk adjustment overpayment, and downstream offsets from glucagon-like peptide-1 therapies. ja.ma/4itgwa6

💬 Viewpoint by Brett Burstein, MDCM, PhD, MPH, Paul Aronson, MD, MHS, Prashant Mahajan, MD, MPH, MBA, and Nathan Kuppermann, MD, MPH: For well-appearing #FebrileInfants who meet modern low-risk criteria, routine #LumbarPuncture may be more likely to cause harm than prevent bacterial meningitis. Newer risk stratification approaches, particularly those incorporating procalcitonin, support more selective cerebrospinal fluid testing even in infants in the first month of life. ja.ma/4z492Ay

Among children conceived using assisted reproductive technology (#ART), childhood cancer incidence was modestly higher than among children not conceived using assisted reproductive technology, although absolute risks were low. The higher risk was concentrated in children conceived after frozen embryo transfer and intracytoplasmic sperm injection, while no association was observed for in vitro fertilization. ja.ma/4BgviZe

Use of #naloxone documented by emergency medical services also declined after May 2023, while total naloxone administrations per 100 overdose activations remained stable. These findings suggest that reduced overdose incidence, rather than increased naloxone use per overdose event, may help explain recent changes in overdose outcomes and may inform medical and public health responses. ja.ma/4jwsgtE

💡 JAMA Insights: #Metabolic dysfunction-associated steatotic liver disease (#MASLD) is the most common cause of chronic #LiverDisease in children and adolescents worldwide and is often asymptomatic. This JAMA Insights indicates that screening with annual alanine aminotransferase testing starting at age 10 years is recommended for children with #obesity and for some children with #overweight or other #cardiometabolic risk factors, which may support earlier diagnosis and referral. ja.ma/4yuLbZy