@JorgensenGroup

Research group based in Aarhus. Asymmetric organocatalysis. Student run account.

 Aarhus, Denmark
groupjorgensen.com
Joined February 2020
  • Tweets169
  • Following273
  • Followers2.8K
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Master's degree✅Congratulations to Mikkel, who successfully defended his Master thesis last week🥳 Well done and all the best moving forward👏#AUChemistry
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Primary amine-catalysis enables stereoselective synthesis of chiral hydrindanone-based motifs as electrophilic scaffolds for covalent protein-labeling🧪 Fresh off the press in Organic Chemistry Frontiers!👏 @OrgChemFront #AUChemistry pubs.rsc.org/qo/article/doi/…

Primary amine-catalysis enables stereoselective synthesis of chiral hydrindanone-based motifs as...

An enantioselective eliminative inverse electron-demand Diels–Alder reaction of α-branched aldehydes enabled by a cinchona alkaloid-based primary amine cat

pubs.rsc.org
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Now the final version of the publication is out🎉 nature.com/articles/s41467-0…

Divergent concerted and stepwise cycloadditions via enantioselective cross-conjugated iminium-ion...

Nature Communications - The authors report experimental and DFT-computational investigations that reveal the versatile reactivities of cross-conjugated unsaturated iminium-ion intermediates. These...

nature.com
Jørgensen Group@JorgensenGroupAug 3
In press at @NatureComms🎉 Divergent [4+2] cycloadditions via asymmetric cross-conjugated iminium-ion catalysis–opens new paths in asymmetric catalysis🧪 Thanks for a fruitful collab to the @houk1000 group. Congrats to @erlaaitz and the team👏 #AUChemistry nature.com/articles/s41467-0…

Divergent concerted and stepwise cycloadditions via enantioselective cross-conjugated iminium-ion...

Nature Communications - The authors report experimental and DFT-computational investigations that reveal the versatile reactivities of cross-conjugated unsaturated iminium-ion intermediates. These...

nature.com
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Replying to @NatureComms
@NatureComms! One of nature’s most fascinating mysteries has been solved: the chirality of the narwhal’s extraordinary tusk.🐋🌀 A beautiful example of how chirality reaches far beyond molecules—and into the structures created by nature. nature.com/articles/s41467-0… 📷Jens Ascanius
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Read more here: politiken.dk/viden/viden/art…

Mysterium om narhvalens stødtand er løst

Narhvalens stødtand er lige, selv om dyret boltrer sig i koldt og kraftfuldt vand. Den robuste struktur har længe været et mysterium, men nu har forskere knækket koden.

politiken.dk
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Excited to share our latest review - now out in Chem Rev! 🙌 Modern higher-order cycloadditions: connecting mechanistic insight with synthetic opportunity 🧪✨ Congrats Anne! 🤩 #AUChemistry doi.org/10.1021/acs.chemrev.…

Modern Higher-Order Cycloadditions

Abstract. Higher-order cycloadditions, defined as pericyclic reactions involving more than 6π-electrons, have emerged as powerful and mechanistically diver

pubs.acs.org
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In press at @NatureComms🎉 Divergent [4+2] cycloadditions via asymmetric cross-conjugated iminium-ion catalysis–opens new paths in asymmetric catalysis🧪 Thanks for a fruitful collab to the @houk1000 group. Congrats to @erlaaitz and the team👏 #AUChemistry nature.com/articles/s41467-0…

Divergent concerted and stepwise cycloadditions via enantioselective cross-conjugated iminium-ion...

Nature Communications - The authors report experimental and DFT-computational investigations that reveal the versatile reactivities of cross-conjugated unsaturated iminium-ion intermediates. These...

nature.com
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Now out in @J_A_C_S!🎉 A new paradigm in controlling the peri- and regioselectivity of troponoids in aminocatalytic [4+2] cycloadditions with α,β-unsaturated aldehydes🧪 Enabled by combining computational and experimental work!🔬 Congrats👏 #AUChemistry pubs.acs.org/jacsat/article/…

Substituent Control of Peri- and Regioselectivity in Enantioselective Aminocatalyzed Cycloadditions...

Abstract. Troponoids exhibit unique reactivity in Diels–Alder and higher-order cycloadditions, since they can partake as 2π-, 4π-, 6π-, and 8π-components,

pubs.acs.org
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Master's degree✅Congratulations to Fabien and Cristina on their successful defenses this Friday👏 It has been a pleasure having you in the group! #AUChemistry
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Social responsibility: Providing homework support in socially disadvantaged residential areas. linkedin.com/posts/faculty-o…
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Just accepted in @JOC_OL! We are lighting up ҉      asymmetric nucleophilic catalysis in [8 + 2] cycloadditions of tropolones🧪 Great collaboration with @KaasikChem and thanks to the team👏! #AUChemistry pubs.acs.org/doi/10.1021/acs…

One-Pot Nucleophilic Organocatalytic Enantioselective [8 + 2] Cycloadditions of Photogenerated...

Abstract. This work presents diazoketones as ketene precursors under photochemical conditions, in conjunction with an isothiourea catalyst, to enable an en

pubs.acs.org
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Beyond classic Diels–Alder: our newest article dives into enamine catalyzed [10+4]- and [10+6] higher-order cycloadditions of 3-oxidopyidinium betaines!🔬 Congrats to @FaghtmannJ and all the authors!👏 Check it out: chemistry-europe.onlinelibra… #AUChemistry

Stereoselective Higher‐Order [10+4]‐ and [10+6] Cycloadditions Between Two Highly Unsaturated and...

Aminocatalytically generated isobenzofulvenes and 3-oxidopyridinium betaines act as ambiphilic reaction partners in orbital-symmetry-allowed [10+4] cycloadditions or formally symmetry-forbidden...

chemistry-europe.onlinelibrary.wiley.com
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Now out in #AccountsofChemicalResearch! Check out our account on enantioselective nucleophilic activation of cyclopropanes⚗️🧪 Congrats @erlaaitzz!👏 @ACSPublications #AUChemistry pubs.acs.org/doi/10.1021/acs…

Nucleophilic Activation of Cyclopropanes for Enantioselective Catalytic Transformations

Conspectus. Activation of cyclopropanes remained a challenging process until the 1980s, when pioneering reports by Wenkert and Reissig showed that cyclopro

pubs.acs.org
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Good news! The ICOS 2026 Early Bird registration deadline is extended to April 30! Don’t miss out - register now and save with the Early Bird rate! Icos2026.com #ICOS2026 #EarlyBird #Chemistry
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Our latest work is hot off the press in @J_A_C_S! We achieve full stereodivergence in Diels-Alder reactions by minimal modifications of a single prolinol-derived catalytic system. Congrats to the whole team! 🙌 @e_marcantonio95 #AUChemistry pubs.acs.org/doi/10.1021/jac…

Stereodivergent Inverse Electron-Demand Diels–Alder Reactions Enabled by Modification of Prolinol...

Abstract. Access to the full array of stereoisomers of molecules bearing multiple stereocenters from the same substrates is an enduring challenge in asymme

pubs.acs.org
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Here we are, once again: After 20 years still opening new doors! 🚀Check out our latest review on diarylprolinol silyl ethers in asymmetric catalysis in @angew_chem✨ #organocatalysis #AUChemistry @e_marcantonio95 onlinelibrary.wiley.com/doi/…

The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis

Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been...

onlinelibrary.wiley.com
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Did you know you can use quinine🍸and cobalt⚗️to design a biomimetic catalyst that imitates the active site of the fungal galactose oxidase enzyme🍄? Congratulations to @SebRicko and the team👏 Out in @Orgmet_ACS! #AUChemistry pubs.acs.org/doi/10.1021/acs…

Mechanistic Insights in Cobalt-Salen Complexes in Oxa-6π Electrocyclizations

Abstract. The present work studies the role half-salen cobalt-complexes in the oxa-6π electrocyclizations of O’Donnell’s Schiff bases. Based on chemical mo

pubs.acs.org
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PhD complete✅ Congratulations to René, who defended his dissertation this Friday🥳 Very impressive work! Thank you to the committee @mogens_br, @LucaDellAmicoLD and Marianne Glasius for joining us at #AUChemistry👏
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Congratulations to Jonas for successfully defending his PhD!🥳 Very well done! Thank you to the committee @mogens_br, Łukasz Albrecht and Marianne Glasius for coming | #AUChemistry🧪
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Ceci n'est pas une SNAr - It's a 𝘵𝘦𝘭𝘦-SNAr🤯 Check out our paper on highly enantioselective nucleophilic aromatic substitution on tropones through a 𝘵𝘦𝘭𝘦-substitution mechanism🧪 Congrats to Valdemar and the team👏 Out now in @J_A_C_S! #AUChemistry pubs.acs.org/doi/10.1021/jac…

An Enantioselective Nucleophilic Aromatic tele-Substitution

Abstract. This work presents the first leaving-group-directed aminocatalytic enantioselective nucleophilic aromatic tele-substitution on the tropone scaffo

pubs.acs.org
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Forget 6-membered rings — 8 is now the magic number!💍An organocatalyzed [4+4] cycloaddition delivers chiral 8-membered rings from furan ortho-quinodimethanes🧪👏 Congrats to the team on this discovery in @angew_chem! #AUChemistry onlinelibrary.wiley.com/doi/…

Organocatalytic Enantioselective [4 + 4] Cycloadditions of Furan Ortho‐Quinodimethanes

The first organocatalytic enantioselective [4 + 4] cycloaddition of furan ortho-quinodimethanes is presented. The reaction proceeds in good yields and with high enantioselectivities allowing for the...

onlinelibrary.wiley.com
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