Jun He (@JunHeJason) profile picture

Jun He

@JunHeJason

PhD, MPH. Postdoctoral Associate. @YalePsych

Joined April 2021
  • Tweets31
  • Following35
  • Followers17
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Photo by Jun He (@JunHeJason)
I am seeking motivated Postdoc and Postgrad trainees to join our multidisciplinary team @YalePsych. We analyze large-scale molecular, clinical, and imaging data to investigate psychiatric disorders, behavioral traits, and other complex phenotypes. nature.com/naturecareers/job…
Postdoc and Postgrad Positions in Computational Biology, Human Genetics, and Molecular Epidemiology...

Postdoc and Postgrad Positions in Computational Biology, Human Genetics, and Molecular Epidemiology...

Postdoc and postgrad positions open in Dr. Renato Polimanti’s group at the Yale University School of Medicine.

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🚨Our new study, led by @JunHeJason, is out on @alzdemjournals! Leveraging @uk_biobank and @AllofUsResearch, we uncovered sex-specific effects of socioeconomic factors and cognitive performance on the assessment of #alzheimers family history. alz-journals.onlinelibrary.w…
Sex differences in the confounders influencing the relationships linking socioeconomic factors and...

Sex differences in the confounders influencing the relationships linking socioeconomic factors and...

INTRODUCTION Limited information is available regarding sex differences in the relationship of socioeconomic status and cognitive performance with Alzheimer's disease and related dementias (ADRD)...

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Our new study led by Dora Koller is out on @JAMAPsych! Through analyses using @uk_biobank and @FinnGen_FI, we assessed the relationships between #endometriosis, #trauma, and #PTSD, uncovering independent links with contact traumas and polygenic risk. jamanetwork.com/journals/jam…
Observational and Genetic Analyses of Traumatic Experiences and Endometriosis

Observational and Genetic Analyses of Traumatic Experiences and Endometriosis

This case-control study analyzes genotypic and phenotypic information from individual-level UK Biobank data, along with genome-wide information from a large meta-analysis and the FinnGen cohort, to...

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Don't miss this episode with @RenatoPolimanti, a human geneticist who recently identified 100+ genes associated with anxiety. He covered how he got started in #science, overcoming the toughest period of his career, life outside the lab, & more. peoplebehindthescience.com/d… @WuTsaiYale
Image from People Behind the Science (@PBtScience)
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Updated #PolimanTEAM picture! Potluck with delicious dishes from around the 🌎. Very thankful to an amazing group advancing #science by bringing together their different perspectives! #ThisIsWhatScientistsLookLike
Image from Renato Polimanti (@RenatoPolimanti)
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Attending #ASHG2024? Take a look at our latest work! On Thursday, @JunHeJason will present a symptom-level analysis of Gulf War Illness and @DavidDavtian1 will show our transcriptomic analyses of COVID-19. On Friday, check out the GWAS of anxiety disorders led by @ElenaFriligkou
Image from Renato Polimanti (@RenatoPolimanti)
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Our new study led by @ElenaFriligkou is on @NatureGenet! Analyzing 1.2M participants, we uncovered genes and biological processes involved in #anxiety risk. Big thanks to current and former #PolimanTEAM members for contributing to this group effort! nature.com/articles/s41588-0…
Image from Renato Polimanti (@RenatoPolimanti)
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Our new preprint led by @JunHeJason is out! Using @uk_biobank and @AllofUsResearch, we characterized sex-specific effects of sociocultural factors when assessing the family history of #alzheimer's disease due to reporting, recalling, and surviving biases medrxiv.org/content/10.1101/…
Sex differences in the associations of socioeconomic factors and cognitive performance with family...

Sex differences in the associations of socioeconomic factors and cognitive performance with family...

INTRODUCTION While higher socioeconomic factors (SEF) and cognitive performance (CP) have been associated with reduced Alzheimer’s disease (AD) risk, recent evidence highlighted that these factors...

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Brain-wide pleiotropy investigation of alcohol drinking and tobacco smoking behaviors medrxiv.org/cgi/content/shor… #medRxiv
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Our new article led by @JunHeJason is out on @Brain1878! Combining #GWAS with imaging data available from @uk_biobank, we explored sex differences linking #brain structure ad function with #hearing problems in adults. @YalePsych academic.oup.com/brain/advan…
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Check out our work about the causal relationships among bipolar disorder, schizophrenia, behavioral traits and suicide attempt! nature.com/articles/s41386-0…
Estimating the direct effects of the genetic liabilities to bipolar disorder, schizophrenia, and...

Estimating the direct effects of the genetic liabilities to bipolar disorder, schizophrenia, and...

Neuropsychopharmacology - Estimating the direct effects of the genetic liabilities to bipolar disorder, schizophrenia, and behavioral traits on suicide attempt using a multivariable Mendelian...

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Very proud of our latest study, where we explored the impact of assortative mating, participation bias and socioeconomic status on the genetic risk of mental health traits. Check it out! 😊 nature.com/articles/s41562-0…
Image from Brenda Cabrera Mendoza (@brendacabreram)
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Another new study led by @brendacabreram is on @NatureHumBehav! Using @PGCgenetics, @VAResearch, and @uk_biobank, we assessed assortative mating, participation bias, and SES effect on behavioral PRS. Big thanks to @LoicYengo for working with us on this! nature.com/articles/s41562-0…
Image from Renato Polimanti (@RenatoPolimanti)
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Our first 2024 preprint led by @ElenaFriligkou is out! We conducted a multi-ancestry #anxiety GWAS of 1.2 million participants combining @uk_biobank, @AllofUsResearch, @FinnGen_FI, @PGCgenetics, #iPSYCH and @VAResearch #MVP. Many novel loci and mechanisms! medrxiv.org/content/10.1101/…
Gene Discovery and Biological Insights into Anxiety Disorders from a Multi-Ancestry Genome-wide...

Gene Discovery and Biological Insights into Anxiety Disorders from a Multi-Ancestry Genome-wide...

We leveraged information from more than 1.2 million participants to investigate the genetics of anxiety disorders across five continental ancestral groups. Ancestry-specific and cross-ancestry...

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A study led by VA Connecticut Healthcare Center and #yalepsych researchers reveals ancestries around the world possess a shared genetic architecture for problematic alcohol use (PAU) – habitual heavy drinking, accompanied by harmful consequences. bit.ly/3uLuTAm
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Our new article led by @dianazanoaga is out on @BiologicalPsyc1! Leveraging @uk_biobank, @FinnGen_FI, and @VAResearch, we identified generalizable effects linking changes in #brain structure and function to #anxiety disorders and symptoms. @YalePsych sciencedirect.com/science/ar…
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Our new study led by @GitaPathakPhD and @ktk_496 is out on @JAMAPsych! Leveraging @uk_biobank, @VUMChealth #BioVU, @VAResearch #MVP, @MassGenBrigham biobank, and @UMich #MGI, we demonstrated #PTSD impact on multiple circulatory and respiratory outcomes. jamanetwork.com/journals/jam…
Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabo...

Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabo...

This genetic association study uses electronic health record data to investigate the association between polygenic score of posttraumatic stress disorder symptom severity and clinical diagnoses and...

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Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration led by @isabelleazimmer is now online @NatureComms - @ucl @KingsCollegeLon @YalePsych. Article here: bit.ly/3RBPkJg Sumstats here: bit.ly/3ZBHoKa
Image from Joseph D. Deak, PhD (@Joseph_Deak)
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Our new preprint led by @dianazanoaga is out! Leveraging @uk_biobank, @VAResearch #MillionVeteranProgram, and @FinnGen_FI, we investigated the relationships linking #anxiety disorders and symptoms to #brain structure and function. medrxiv.org/content/10.1101/…
Brain-Wide Mendelian Randomization Study of Anxiety Disorders and Symptoms

Brain-Wide Mendelian Randomization Study of Anxiety Disorders and Symptoms

Background To gain insights into the role of brain structure and function on anxiety (ANX), we conducted a genetically informed investigation leveraging information from ANX genome-wide association...

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🚨📢 We have open postdoc and postgrad positions to work on projects funded by @NIMHgov, @OneMindOrg, @NIDAnews, @VAResearch, and @Alkermes! Please reach out to learn more about these opportunities. #Retweets appreciated. @YalePsych @YaleGenetics @WuTsaiYale @KavliAtYale
Image from Renato Polimanti (@RenatoPolimanti)
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