Kristen Demoruelle (@KDemoruelle) header
Kristen Demoruelle (@KDemoruelle) profile picture

Kristen Demoruelle

@KDemoruelle

Rheumatologist | Interested in the lung in the development of RA, NETs, RA-ILD and sex differences in RA | @CURheumatology

Joined March 2023
  • Tweets11
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  • Followers48
Kristen Demoruelle retweeted
Jason S Knight (@jasonsknight) profile picture
Jason S Knight@jasonsknight30 May 2024
🫚👀 Should we all be eating more of this spice? @BBC bbc.co.uk/food/articles/ging…
Should we all be eating more of this spice?

Should we all be eating more of this spice?

Lots of things can make us feel sick from time to time. From pregnancy and anxiety to stomach bugs and motion sickness. But can this commonly used spice help? And does it have other health benefits?

bbc.co.uk
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"Why Do Women Have a Higher Risk of Developing Autoimmune Disorders?" Article and Q&A with @KDemoruelle Kristen Demoruelle, MD, PhD in the Division of Rheumatology in CU Anschutz news: news.cuanschutz.edu/medicine…
Why Do Women Have a Higher Risk of Developing Autoimmune Disorders?

Why Do Women Have a Higher Risk of Developing Autoimmune Disorders?

It’s complicated, says CU associate professor of medicine Kristen Demoruelle, MD, PhD, but genetics, sex hormones, and different environmental factors are likely at play.

news.cuanschutz.edu
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Kristen Demoruelle retweeted
NIAMS (@NIH_NIAMS) profile picture
NIAMS@NIH_NIAMS14 Mar 2024
#NIAMSfunded news: A study from @cudeptmedicine explains how gut bacteria can break down tryptophan, a common amino acid found in most diets, into an inflammatory chemical that leads to collagen-induced arthritis in mice. Read the #OpenAccess paper: jci.org/articles/view/167671
The paper’s graphical abstract illustrating 5 steps: 1) Intestinal dysbiosis in CIA enhances indole production. 2) Indole promotes a pro-inflammatory cytokine signature. 3) Indole skews Th17:Treg ratio. 4) Indole alters anti-CII complement binding, IgG2b isotype switching, and galactosylation. 5) Indole is required for the development of collagen-induced arthritis.

ALT The paper’s graphical abstract illustrating 5 steps: 1) Intestinal dysbiosis in CIA enhances indole production. 2) Indole promotes a pro-inflammatory cytokine signature. 3) Indole skews Th17:Treg ratio. 4) Indole alters anti-CII complement binding, IgG2b isotype switching, and galactosylation. 5) Indole is required for the development of collagen-induced arthritis.

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DOM faculty @KristiKuhn’s latest research, published in @jclinicalinvest, explores how tryptophan, often a force for good, can be converted into a pathway for inflammatory disease such as rheumatoid arthritis. Learn more ⬇️ bit.ly/48MIAgF
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Kristen Demoruelle retweeted
ACR_Journals (@ACR_Journals) profile picture
ACR_Journals
@ACR_Journals1 Mar 2024
Expansion of HLA-DR+ Tph cells and CXCR5−CD11c−CD38+ naive B cells in a cohort of ACPA+ individuals, incl. those who developed inflammatory arthritis & classified RA, supports a key role of these cells in transition from pre-RA to classified RA In A&R loom.ly/dGY3Ezk
Expansion of HLA-DR+ Peripheral Helper T and Naïve B cells in Anti-Citrullinated Protein Antibody-Positive Subjects At-Risk for Rheumatoid Arthritis. Graphical abstract created with BioRender

ALT Expansion of HLA-DR+ Peripheral Helper T and Naïve B cells in Anti-Citrullinated Protein Antibody-Positive Subjects At-Risk for Rheumatoid Arthritis. Graphical abstract created with BioRender

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See our new collaborative study that found elevations of peripheral Tph cells in pre-RA #rheumatoidarthritis @CURheumatology bit.ly/3SUi677
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Kristen Demoruelle retweeted
Jason S Knight (@jasonsknight) profile picture
Jason S Knight@jasonsknight22 Sep 2023
news.cuanschutz.edu/news-sto…
New Research Adds Evidence to the Benefits of Ginger Supplements for Treating Autoimmune Diseases

New Research Adds Evidence to the Benefits of Ginger Supplements for Treating Autoimmune Diseases

New Research Adds Evidence to the Benefits of Ginger Supplements for Treating Autoimmune Diseases

news.cuanschutz.edu
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Kristen Demoruelle retweeted
Jason S Knight (@jasonsknight) profile picture
Jason S Knight@jasonsknight22 Sep 2023
🫚🕸️👀 Ginger intake suppresses neutrophil extracellular trap formation in autoimmune mice and healthy humans insight.jci.org/articles/vie… @KDemoruelle
Image from Jason S Knight (@jasonsknight)
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Kristen Demoruelle retweeted
ACR_Journals (@ACR_Journals) profile picture
ACR_Journals
@ACR_Journals28 Aug 2023
Anti-citrullinated protein antibodies both prevent and help to reduce joint inflammation in the early phases of an animal model of arthritis. Do certain autoantibodies arise as compensatory mechanisms to mitigate inflammation? In A&R loom.ly/7CXYPrA
Figure created with BioRender.com

ALT Figure created with BioRender.com

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👏Congratulations @FanZhang_Jessie @CURheumatology on being a 2023–24 ANRF Scholar! #RheumatoidArthritis
Arthritis National Research Foundation (@CureArthritis) profile pictureArthritis National Research Foundation
@CureArthritis6 Jul 2023
Announcing the 2023 - 2024 ANRF Scholars! "We could not be more confident in the abilities of this exceptional cohort to improve our understanding of these complex diseases and bring us closer than ever to a cure for #arthritis," says CEO Emily Stormoen. bit.ly/23Scholars
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