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Kurrasch Lab (@KurraschLab) profile picture

Kurrasch Lab

@KurraschLab

Managed by Deepika Dogra. Uncovering the molecular basis of neurological development and disorders by using mice, zebrafish and human brain organoids. @UCalgary

 University of Calgary, Canada
cumming.ucalgary.ca/labs/developing-brains
Joined January 2020
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  • Followers349
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Photo by Kurrasch Lab (@KurraschLab)Photo by Kurrasch Lab (@KurraschLab)Photo by Kurrasch Lab (@KurraschLab)Photo by Kurrasch Lab (@KurraschLab)Photo by Kurrasch Lab (@KurraschLab)Photo by Kurrasch Lab (@KurraschLab)Photo by Kurrasch Lab (@KurraschLab)Photo by Kurrasch Lab (@KurraschLab)
I'm happy to share our latest work published in @PLOSBiology. Here we describe a zebrafish model of SLC13A5 epilepsy and show how modulating zinc chelation and NMDA signaling can prevent seizure-like events. 1/2 journals.plos.org/plosbiolog…
Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish...

Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish...

Mutations in the SLC13A5 citrate transporter have been linked to epilepsy in humans. In this study the authors generate a new zebrafish model of slc13a5 epilepsy and reveal that in this model,...

journals.plos.org
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So happy to share the preprint of our work on zebrafish model of SLC13A5 epilepsy @KurraschLab @TESSResearch 🐟🧠 Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor signaling biorxiv.org/content/10.1101/…
Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor...

Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor...

SLC13A5 encodes a citrate transporter highly expressed in the brain important for regulating intra- and extracellular citrate levels. Mutations in this gene cause a rare infantile epilepsy characte...

biorxiv.org
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Kurrasch Lab retweeted
Matt Hill (@canna_brain) profile picture
Matt Hill@canna_brain31 Aug 2023
We are hiring a Tier 1 Canada Research Chair (level of Full Professor) in the broad area of Brain Circuits. Come join @drstephieb @painandpoppies @neurophy @KurraschLab @MayoOnTheBrain @d_sargin and many more at @HotchkissBrain Details for position 👇 medicine.careers.ucalgary.ca…
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A huge thanks to T. Boone Pickens Foundation for supporting the research at the Hotchkiss Brain Institute!! Delighted to have our brain organoid work featured today! @HotchkissBrain @UCalgary @KurraschLab Don't miss the video!😉🧠 calgary.ctvnews.ca/t-boone-p…
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Great #ENDO2023 symposium on tanycytes. Got to see the new work of ⁦@SethBlackshaw⁩ and ⁦@KurraschLab⁩!
Image from Lori Raetzman (@PrairieLTR)
Image from Lori Raetzman (@PrairieLTR)
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Glyphosate Toxicity: In Vivo, In Vitro, and Epidemiological Evidence. @KurraschLab #FreeToRead doi.org/10.1093/toxsci/kfad0…
Image from Toxicological Sciences (@ToxSci)
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We are excited to host the ZDMS Neural Disorders RIG virtual seminar on May 24. Please join us for these wonderful talks. zdmsociety.org/2022-zdms-rig…
Summer Thyme (@summerbthyme) profile pictureSummer Thyme@summerbthyme2 May 2023
It's that time of year again! @KarinTuschl @deepika_dogra1 and I are excited to host the ZDMS Neural Disorders RIG virtual seminar on May 24th. Anyone can attend. We will hear from @PascaleBomont @GulizOzcan @VatsalaT and Cheol-Hee Kim. Hope you will join: zdmsociety.org/2022-zdms-rig…
Image from Summer Thyme (@summerbthyme)
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Dr. Deborah Kurrasch is a Professor @UCalgaryMed and Scientist @UofCr4kids @HotchkissBrain. Dr. Kurrasch is the CEO/Co-Founder of Path Therapeutics, a drug discovery company with an initial focus on brain disorders.⁠ ⁠ Scientist to Entrepreneur Panel: neurovation.eventbrite.ca
Image from Hotchkiss Brain Institute (HBI) (@HotchkissBrain)
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Closing out '22 well!!🎄 I am thrilled to have received the "Owerko Centre Early Career Investigator Grant 2022" for my work on developmental epileptic encephalopathies. Big thanks to @owerkocentre @UofCr4kids @KurraschLab 🐟 🧫🧠
Image from Deepika Dogra, PhD (@deepika_dogra1)
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Kurrasch Lab retweeted
ACHRI (@UofCr4kids) profile picture
ACHRI@UofCr4kids15 Dec 2022
Thank you @ArrietaLab and @KurraschLab for sharing the innovative approaches your labs are undertaking - transforming care - and helping move towards ending the diagnostic odyssey for kids and families @UofCr4kids @UCalgaryMed @UCalgaryPeds @UCalgary @ACHFKids
Image from ACHRI (@UofCr4kids)
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Really excited to receive the Early Career Investigator Grant. Big thanks to TESS Research Foundation @TESSResearch @KurraschLab #SLC13A5
TESS Research Foundation (@TESSResearch) profile pictureTESS Research Foundation@TESSResearch12 Oct 2022
We are excited to introduce our early career investigators! 👏 TESS recently awarded 4 research grants to broaden & deepen our understanding of SLC13A5 & develop open-science tools that can be used by other basic scientists. 💪💜 Learn more ➡️ bit.ly/3RYcRke
Image from TESS Research Foundation (@TESSResearch)
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New work from @deepika_dogra1 & @KurraschLab
bioRxiv Neuroscience (@biorxiv_neursci) profile picturebioRxiv Neuroscience@biorxiv_neursci30 Sep 2022
kcna1a mutant zebrafish as a model of episodic ataxia type 1 and epilepsy biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Kurrasch Lab retweeted
Rosin Lab (@RosinLab) profile picture
Rosin Lab@RosinLab29 Mar 2022
Happy to share some recently published work from my postdoc with @KurraschLab on the impact of gestational BPA exposure on embryonic hypothalamic microglia: frontiersin.org/articles/10.…
Frontiers | Gestational Bisphenol A Exposure Impacts Embryonic Hypothalamic Microglia Numbers,...

Frontiers | Gestational Bisphenol A Exposure Impacts Embryonic Hypothalamic Microglia Numbers,...

Microglia are a resident population of phagocytic immune cells that reside within the CNS. During gestation, they are highly sensitive to their surrounding e...

frontiersin.org
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30-40% of people living with epilepsy experience resistance to current medications. Dr. @KurraschLab's research works on tailored medication using genetic modelling, which inspired Path Therapeutics. pathbio.com #epilepsy #epilepsyawareness #epilepsyeducation
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Dr. Deborah Kurrasch's lab has developed a novel drug screening platform to uncover therapies for children with refractory epilepsy. Watch Dr. Kussasch on 17 minutes of science discussing why zebrafish are particularly well suited for anti-seizure research invivobiosystems.com/17-minu…
Image from Hotchkiss Brain Institute (HBI) (@HotchkissBrain)
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Congratulations to HBI member, @DeborahKurrasch!
ACHRI (@UofCr4kids) profile pictureACHRI@UofCr4kids2 Nov 2021
Congratulations to @UofCr4kids @DeborahKurrasch for being awarded Outstanding Woman in Innovation for her work in rare genetic epilepsies in children! bit.ly/3bBM2j0 @UCalgary @UCalgaryMed @HotchkissBrain @ACHFKids @TSGICorp
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Kurrasch Lab retweeted
Neuron (@NeuroCellPress) profile picture
Neuron@NeuroCellPress16 Sep 2021
New issue is out, with an origami brain on the cover! For @sisu_han & coll.'s paper on niche cells essential to organize patterns of neurogenesis (bit.ly/2XrZcvM). With a preview by Borrell (bit.ly/3CltBKY) Check out the full issue here: cell.com/neuron/current
Image from Neuron (@NeuroCellPress)
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Julien Muffat (@tinyglue) profile picture
Julien Muffat@tinyglue24 Aug 2021
Great session on microglial biology @CAN_ACN 2021, with really exciting work by Jasna Kriz, @jrplemel, @KurraschLab and @TiinaTmk. Here's to meeting in person soon :)
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ACHRI (@UofCr4kids) profile picture
ACHRI@UofCr4kids30 Apr 2021
Brilliant research in @KurraschLab discovering link between prenatal stress and disruptions in brain development, especially in male offspring. The research is published in Developmental Cell. ow.ly/5RG750EBW69 @UCalgaryMed @HotchkissBrain @ACHFKids
Image from ACHRI (@UofCr4kids)
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ACHRI (@UofCr4kids) profile picture
ACHRI@UofCr4kids24 Apr 2021
Congratulations to the team! Thank you to our community for supporting child health and wellness research. @ACHFKids
Kurrasch Lab (@KurraschLab) profile pictureKurrasch Lab@KurraschLab21 Apr 2021
Our recent publication is now online at Dev Cell- “A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors”, in collaboration with Biernaski lab. Congratulations to all the authors! @Dev_Cell @UofCr4kids
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