@LabDomercq

We investigate oligodendrocytes/myelin and microglia in myelination/remyelination at @AchucarroGlia and @upvehu

 Bilbao, Spain
achucarro.org/es/laboratory/glia-matrix-biology/
Joined December 2022
  • Tweets462
  • Following404
  • Followers409
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Maria Domercq retweeted
IdoAmitLab@IdoAmitLabOct 16
What comes after M1/M2? In our Perspective with @FGinhoux in @ImmunityCP we explore how single-cell technologies and AI can decode the gene programs macrophages use across tissues & microenvironments, and how this modular view could transform immunotherapy cell.com/immunity/abstract/S…

Embracing macrophage complexity for research and translation

Ginhoux, Mulder, Arcila-Barrera, and Amit argue that macrophage identity is best understood not as a set of discrete subsets or a binary M1/M2 axis but as combinations of modular gene programs. They...

cell.com
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Maria Domercq retweeted
Federico Soria@SoriaFNOct 16
Buscamos candidato para la convocatoria Juan de la Cierva #JdC2026🧠 El proyecto se desarrollará en el @GlioMatrixLab con @LabDomercq y @SoriaFN en Achucarro, para estudiar la glía y la matriz extracelular en neurodesarrollo. Más info en drive.google.com/file/d/1d_j…

JdC_2026_Gliomatrix.pdf

drive.google.com
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Maria Domercq retweeted
SENC@SENC_Sep 22
🧠⏰Quedan pocos días para enviar abstracts al 2nd Iberian Glia Meeting. Organizado por @GlialRede y @redglial, se celebrará online los días 25 y 26 de noviembre 🗓️Deadline: 25 de septiembre 🔗redeglial.weebly.com/2nd-ibe… #CallForAbstracts #Glia #Neurociencia
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A wonderful close to#AIGS2026!! Three days of spectacular talks on glial cells, inspiring discussions and great moments with the students. Huge thanks to all the speakers!!! Grateful to @pie_upvehu @AchucarroGlia @upvehu and @walkonproject for their support!! See you in 2028...
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Maria Domercq retweeted
GlioMatrixLab@GlioMatrixLabSep 17
First day of Glia School #AIGS2026 @upvehu @AchucarroGlia
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Maria Domercq retweeted
Federico Soria@SoriaFNSep 16
#AIGS2026, the III Achucarro International Glia School starts today. 36 students, 14 speakers, mentoring sessions and many collaborators. 3 days of glia biology in the stunning beach of Plentzia. Thanks to @upvehu, @AchucarroGlia and the sponsors for their support.
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Maria Domercq retweeted
GlioMatrixLab@GlioMatrixLabSep 16
Great lineup of speakers! Students from 15 countries! Exciting talks and discussions.
Federico Soria@SoriaFNSep 16
#AIGS2026, the III Achucarro International Glia School starts today. 36 students, 14 speakers, mentoring sessions and many collaborators. 3 days of glia biology in the stunning beach of Plentzia. Thanks to @upvehu, @AchucarroGlia and the sponsors for their support.
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Maria Domercq retweeted
JuliRosa_Neuro@JulirosaNeuroSep 16
Heading to the #Achucarro International #Glia School! Excited to join this edition as a professor alongside such outstanding colleagues in the field. @AchucarroGlia @HNParaplejicos @idiscam @SENC_
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Excited to be celebrating day one of the Achucarro International Glia School in a beautiful location. Excellent speakers, interesting debate!!!
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Maria Domercq retweeted
Nat Rev Neurology@NatRevNeurolAug 26
Oligodendrocyte dysfunction in human age-related cognitive decline idp.nature.com/authorize?res…

Oligodendrocyte dysfunction in human age-related cognitive decline

Nature Medicine - This study identifies oligodendrocytes as active contributors to cognitive decline in aging, by leveraging a unique human brain bank with more than 70 years of associated...

nature.com
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Maria Domercq retweeted
Tess Dierckx@TessDierckxAug 7
How does aging impair OPC function? The core circadian factor BMAL1 is disrupted in aging and MS, driving metabolic deficits, senescence, and altered time-of-day dynamics. Exciting part? Time-based BMAL1-SIRT2 targeting optimizes demyelination recovery. cell.com/neuron/fulltext/S08…

Temporal changes in metabolism guide oligodendrocyte precursor cell dynamics in aging and multiple...

Aging disrupts the circadian transcription factor BMAL1 in oligodendrocyte precursor cells (OPCs), with Bmal1 loss driving OPC metabolic dysfunction and senescence. Evening-timed therapeutic interv...

cell.com
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Exciting work!!
Andrew Octavian Sasmita@AOSasmitaJul 31
An activity-modulated transport route across myelin (TRAM) for motor-driven organelle transfer in oligodendrocytes nature.com/articles/s41593-0… Congratulations @DrChapple @Lina_Komarek @KlausNave @JuliaEdgar1 🎉

An activity-modulated transport route across myelin (TRAM) for motor-driven organelle transfer in...

Nature Neuroscience - Axons require intracellular transport of cargoes between the soma and the terminus. The authors show a related logistical challenge exists at smaller scale with respect to the...

nature.com
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Maria Domercq retweeted
GlioMatrixLab@GlioMatrixLabJul 30
Summer lunch!
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Maria Domercq retweeted
Developmental Cell@Dev_CellJul 21
Glia don't just "support" neurons - they sculpt circuits. Sakers, Sheehan, Xin, Schafer & Eroglu review 25 years of evidence showing how astrocytes, microglia & oligodendrocytes actively orchestrate synapse formation, pruning & circuit maturation 🧠 cell.com/developmental-cell/…
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Maria Domercq retweeted
John Lukens@LukensJohnRJul 21
Localized PD-1 CAR T therapy reprograms neuroinflammation. @CellCellPress cell.com/cell/fulltext/S0092…
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Maria Domercq retweeted
Federico Soria@SoriaFNJul 10
Last day of #FENS2026 Barcelona. One last @AchucarroGlia family photo before we all scatter back to Bilbao. Great conference. Congratulations to the organizers @FENSorg @SENC_
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Maria Domercq retweeted
Rosa Paolicelli@rosa_paolicelliJul 8
Our work on #Microglia and #TDP-43 in early #brain development is finally out @NatureNeuro! Congrats to the brilliant @AnneCompagnion and thanks to the many collaborators!!! Enjoy the read!! :) nature.com/articles/s41593-0…

Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice

Nature Neuroscience - Compagnion et al. show that TDP-43 loss in microglia causes myelin defects, oligodendrocyte precursor cell imbalance and motor deficits in mice. They identify TDP-43 as a...

nature.com
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The shareable link is not working properly, you can access the article here nature.com/articles/s41467-0…

Monocarboxylate transporter 2 regulates maintenance of myelin and axonal integrity by oligodendro...

Nature Communications - Metabolic determinants of white matter integrity remain elusive. Here, the authors show downregulation of MCT2 in oligodendrocytes in progressive MS, and then demonstrate...

nature.com
Vanja Tepavcevic@TepavcevicVanjaJun 25
Our article is in press @NatComms! We show that MCT2 regulates oligo metabolism to promote maintenance of myelin and axonal integrity. Kudos to all authors! Co-1st @oligomoon & @Leire18234919, @solerirs @UBB_CIPF @matutelab @maaryameliemas @LabDomercq👇rdcu.be/fqmhQ
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Excellent opportunity for a PhD working in astrocytes in a top group!! xitter.cf/i/status/2074117788872…
IDISCAM@idiscamJul 6
🆕 El grupo de la Dra. Juliana M. Rosa crece con un contrato predoctoral PREP2024 para el estudio de las señales a través de astrocitos en la discriminación sensorial Financiado por @CienciaGob en el @HNParaplejicos #IDISCAM #Astrocitos #PreDoc
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Maria Domercq retweeted
GlioMatrixLab@GlioMatrixLabJul 7
Come and discover our poster at #FENS2026! “PIEZO1 REGULATES MICROGLIAL MOTILITY AND RESPONSES TO EXTRACELLULAR MATRIX REMODELING DURING ZEBRAFISH BRAIN DEVELOPMENT” presented by Irene Tomé Velasco 📌 Poster number: PS01-07AM-113 📅 July 7 🕑 11:30–13:00 Stop by and say hi!
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