Playing with #singlemolecules, bending light, and algorithms to see really small things. Led by Matthew Lew, Associate Professor @WashUESE @WashUengineers
St Louis, MO
Joined October 2015
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It's great to see Alex's undergraduate work on optimal excitation polarization modulation now out in #BOE. He will be joining us as an #ImagingScience PhD student in the New Year! doi.org/10.1364/BOE.607950
@WashUESE alum Alex Nie with Matthew Lew found that polarized light patterns can improve the precision of microscopes used to measure the orientation of single molecules.
engineering.washu.edu/news/2…
Lew Lab @ WashU retweeted
Shooting oneself in the foot?
Nope.
Shooting oneself in the prefrontal cortex.
U.S. President Donald Trump has fired all 24 members of the National Science Board, the body that oversees the National Science Foundation. Many science advocates see it as the latest step by his administration to erode—some would say destroy—the independence of the 76-year-old research agency. scim.ag/4eGM0YS
Lew Lab @ WashU retweeted
For this #SpotlightSunday, view this Spotlight by Matthew D. Lew of #OPG_JOSA_A: Surface orientation ambiguity for single molecules at dielectric interfaces bit.ly/4kh9vJ0 #OrientationImaging #RefractiveIndex @UTArlington
Very happy to share this news of my election to become an #OpticaFellow. I'm grateful to my many students and mentors over the years. Happy Thanksgiving!
Meet the new #OpticaFellows!
The Optica Board of Directors is pleased to announce that 121 members from 23 countries have been elected as Fellows for their outstanding contributions and service to Optica and the community.
Find the full class: bit.ly/4rgXHtn
Lew Lab @ WashU retweeted
How do discoveries in the lab become lifesaving treatments?
This updated infographic provides a big-picture view of the R&D pipeline, illustrating the public-private sector continuum from discovery to delivery. It visualizes just how much innovation depends on collaboration among multiple sectors and stages of research.
Use this resource in your outreach to show how progress slows when any segment is underfunded or otherwise weakened.
#FundScience #MedicalInnovation #HealthResearch
Happy to share our recent review in @NaturePhotonics on #singlemolecule #orientation #localization #microscopy, co-authored with Sophie Brasselet @CNRS @InstitutFresnel. See molecule motions and rotations in action! doi.org/10.1038/s41566-025-0…
"A new polarized dual-view inverted selective-plane illumination microscope (pol-diSPIM), coupled with engineering insights provided by its imaging model, offers an exciting way forward." My commentary is online in PNAS pnas.org/doi/10.1073/pnas.25…
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates: nature.com/articles/s41467-0…