Daily news and insights on research, investments and technologies that extend life and improve the quality of that extended life. #Longevity

London
Joined December 2018
What if how well we function matters as much as what’s been diagnosed? Dr John Beard explains why intrinsic capacity could change how we think about aging and care. #longevity #geroscience #intrinsiccapacity
1
321
As pharma shops for de-risked science, venture money is moving later and concentrating in fewer, bigger bets – our report tracks the shift. vist.ly/5pi6t #longevity #geroscience #pharma #venturecapital #biotech
316
Avaí Bio and Austrianova began work with Ospedale San Raffaele on protecting lab-grown insulin cells from the immune system. vist.ly/5phkd #longevity #geroscience #AvaíBio #Austrianova #insulin
4
364
Nature Biotechnology paper offers a better way to judge models that predict gene effects. Shift plans to use it to hunt for aging targets. vist.ly/5ph3v #longevity #geroscience #NatureBiotechnology #geneeffects #aging
2
2
388
Insilico Medicine nominates ISM9546, an oral VAV1 degrader designed with generative AI, as a preclinical candidate for autoimmune disease. vist.ly/5pghr #longevity #geroscience #InsilicoMedicine #ISM9546 #autoimmunedisease
1
4
6
482
KAUST and Oxford researchers used a transistor-based sensor to read three forms of alpha-synuclein, reaching 90.9% accuracy in a small study. vist.ly/5pgbw #longevity #geroscience #KAUST #Oxford #alphasynuclein
2
2
1
489
Rona Therapeutics grants Roche worldwide rights to an ALK7-silencing candidate, with up to $1.06b in further milestones on the table. vist.ly/5pg62 #longevity #RonaTherapeutics #Roche #ALK7 #biotech
1
455
Intrinsic capacity isn’t simply fitness, independence or being disease-free. It spans cognition, locomotion, psychological and sensory capacity, and vitality, but there’s no universally accepted composite score yet. #longevity #geroscience #intrinsiccapacity
2
3
414
An up to $28.3 million ARPA-H award aims to stretch Bexorg’s human brain platform from 24 hours to two weeks. vist.ly/5pcav #longevity #geroscience #ARPAH #Bexorg #brainresearch
1
3
4
550
German biotech MODAG won for pairing a CE-marked diagnostic with a drug candidate that targets the same protein. vist.ly/5pbv5 #longevity #geroscience #MODAG #biotech #diagnostics
1
2
590
Adjusting for how advanced patients’ disease was at the start lifts the Phase 2 result. The method was added after the trial began. vist.ly/5pbbj #longevity #geroscience #Phase2 #clinicaltrial #clinicalresearch
1
3
2
436
Cala Health’s kIQ Plus now offers three stimulation modes and a calibration before each use, and it’s available across the US. vist.ly/5pb5h #longevity #CalaHealth #kIQPlus #stimulation #digitalhealth
1
1
3
516
Buck Institute’s Eric Verdin joins clinic leaders to tackle the ‘luxury diagnostic’ trap and the push for standardized care. vist.ly/5pax4 #longevity #geroscience #BuckInstitute #EricVerdin #standardizedcare
2
3
524
BodySpec’s new storefront targets muscle loss from GLP-1 weight loss drugs, with scans said to take about 12 minutes. vist.ly/5p8bg #longevity #bodyspec #muscleloss #glp1 #weightloss
2
1
6
621
VectorY is growing PIONEER-ALS from 12 to 36 participants to test VTx-002, an antibody therapy aimed at the protein TDP-43. vist.ly/5p7v2 #longevity #geroscience #vectory #pioneerals #vtx002
3
3
607
A quick digital memory test and a lab assay for brain disease are teaming up to flag neurodegeneration earlier. vist.ly/5p7h3 #longevity #geroscience #memory #braindisease #neurodegeneration
2
7
568
A Censuswide survey commissioned by PortionIQ finds confidence is lower among longer-term users, though it’s a snapshot from one brand. vist.ly/5p6x7 #longevity #censuswide #portioniq #survey #confidence
2
5
476
Forget the diagnosis count. The researcher who helped the WHO reframe aging says function, not disease, is the better yardstick. vist.ly/5p6hf #longevity #geroscience #aging #function #disease
2
2
6
578
Jupiter Neurosciences also hired an adviser to explore a sale or licensing of its assets while the 30-person trial gets underway. vist.ly/5p52r #longevity #jupiterneurosciences #trial #licensing #assets
2
4
22
1,097
The whole-body scan company is launching a research network with 50+ institutions. Early findings come with some big open questions. vist.ly/5nz9h #longevity #research #network #institutions #findings
1
5
10
698