Research Scientist @SINTEF. Metabolic Engineering, from computer to cultivation. Biotech for healthy environment. ♻️Carbon! Leisure 🚲, 🗻 scrambler. Hi =)
Trondheim, Norway
Joined October 2019
- Tweets578
- Following591
- Followers270
- Likes2.8K
Markus Janasch retweeted
Last work from the group out of the press in @NatureComms !
Here we looked at baker yeast 🥐🍺 through the single-cell lenses 🔎🦠
We found out genetically identical subpopulations with different behaviours emerging in response to amino acid identity.
nature.com/articles/s41467-0…
Markus Janasch retweeted
In our new paper at Cell (@CellCellPress), we reveal secrets of how the third form of life, archaea, make energy. We uncover new lineages of hydrogen-using enzymes, both minimal and complex. These help archaea thrive in all sorts of extreme environments. sciencedirect.com/science/ar…
Markus Janasch retweeted
Clocking out and letting go to unleash green biotech applications in a photosynthetic host | PNAS pnas.org/doi/10.1073/pnas.23…
Markus Janasch retweeted
Was fun to pitch our research in 2 minutes for Eye-Openers videos! See for a simple intro (Dutch + English subs) in why and how we developed bacterial cell factories to convert CO2 in products @MIB_WUR @WUR, thanks to @KNCVchemie support
sciencelink.net/media/produc…
Markus Janasch retweeted
The proteome is a terminal electron acceptor biorxiv.org/content/10.1101/…
Markus Janasch retweeted
We are hiring: Phd Position in computational biology
jobs.unibas.ch/offene-stelle…
Markus Janasch retweeted
Explainable #machinelearning models were developed to understand the effects of 30 different carbon sources on E. coli growth and their mechanisms down to the individual metabolic steps ➡️ embopress.org/doi/full/10.10… #metabolism #metabolicengineering
Markus Janasch retweeted
Doctoral researcher's position in my new project at @UniTurku is now open! Apply here to do a #PhD studying the role of the proton motive force in regulation of #photosynthesis in #cyanobacteria: ats.talentadore.com/apply/va…
#phdpositions
Markus Janasch retweeted
What drives microbiome complexity? Can Shannon's entropic measures explain them? Check our new paper in PNAS led by @sfiscience @MIT Serguei Saavedra with our theoretical model of microbiome community transitions, from guts to marine ecosystems. pnas.org/doi/10.1073/pnas.23…
Markus Janasch retweeted
A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle | Nature Communications @NatureComms nature.com/articles/s41467-0…
Markus Janasch retweeted
Our latest work on metabolic engineering using kinetic models and process systems engineering methods is out nature.com/articles/s41467-0…! Congrats to Bharath (@bharathnarayana), Daniel (@realDRWeilandt
), Maria, Misko (@Misko_L34), and @Vassily_13
.
Markus Janasch retweeted
Our paper on scrambling the human genome is finally out 🍳 ! What a crazy journey this has been with my fantastic collaborator @JonasKoeppel 🎉
Make sure to check out his awesome 🧵 about our technology to create genetic diversity in human cells! 🧬
What if we could inducibly create thousands of structural variants and ecDNAs in human cells and see which ones survive?
biorxiv.org/content/10.1101/…
I’m excited to share our story on scrambling the human genome by combining prime editing, repetitive elements, and recombinases. A🧵
Markus Janasch retweeted
The book is on sale right now - save $17.99 on the ebook or paperback.
routledge.com/Nonlinear-Dyna…
Markus Janasch retweeted
Enrichment methods find perturbed processes in omics, but can we better account for pathway functions? See our update to metabolic function analysis in CellFie, now with protein secretion (critical to cell-cell interactions). Led by Helen Masson
authors.elsevier.com/sd/arti…
Markus Janasch retweeted
Truly massive bacteria—one million times the volume of E. coli—live inside the unicornfish. Explore its genome and uncover the secrets behind the gargantuan size of this bacterial behemoth.
In @Physorg_com: ow.ly/tOmH50QluEJ
Read the full study: ow.ly/4vHN50QluEK
ALT The metabolic and biosynthetic landscape of Ca. E. viviparus. The gray and orange outlines represent the cell envelope. Specific metabolic pathways are highlighted in colored boxes with key intermediates shown. Catabolic steps or transport pathways are depicted by black lines with arrowheads, and dotted lines stand for missing steps of pathways.
Markus Janasch retweeted
Great visualization of something terrible, a climate tipping point.
This shows how a rainforest can tip into rapid deforestation with longer droughts, as global warming worsens.
Similar tipping points can cause changes in ocean currents and ice sheets👇
Markus Janasch retweeted
Happy to share our new design of a C1/formaldehyde assimilation pathway out on @NatureComms. Congrats to @TongWu_C and all. Thanks to supports from @WeTheBarEvenLab, Philippe Marliere, @SteffenNLindner, and @erblabs! #MetabolicEngineering #SynBio nature.com/articles/s41467-0…
Markus Janasch retweeted
Excited to share our work @erblabs out today in @NatureCatalysis. A new synthetic CO2-fixation cycle, the THETA cycle, is designed, constructed in vitro, and modularly implemented in E. coli. Step by step, we are bringing synthetic CO2 fixation to life. nature.com/articles/s41929-0…
Markus Janasch retweeted
*Open position*
Are you interested in the fundamental #regulation of #photosynthesis and the role of #flavodiiron proteins? We have an opening for #PhD student/#PostDoc in our group focusing on this topic. See link for more info.
Please RT ats.talentadore.com/apply/tu…