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Twitter account Universitaire Master Evidence Based Practice in Health Care, clinical epidemiology, Amsterdam UMC|AMC-UvA.

Amsterdam
Joined January 2013
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Master EBP, AMC-UvA retweeted
2023, and I am still evaluating study protocols in which researchers write "if results are positive, they will be published".😳
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Master EBP, AMC-UvA retweeted
Great new read from @stephensenn for any trialist, observationalist or casualist with an interest in analyzing data that are nested (or clustered, multilevel,...) doi.org/10.1007/s10654-022-0…
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Master EBP, AMC-UvA retweeted
No matter what you were taught, don't bother to test for proportional hazards in survival analyses. Hazards are never proportional because hazard ratios vary over the follow-up if treatment has an effect on survival. @mats_julius and I explain it here: jamanetwork.com/journals/jam…
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Master EBP, AMC-UvA retweeted
From its inception, EBM has had its critics. In 2008 we were asked to engage in a debate about whether EBM has a sound scientific basis. The paper we wrote for the debate presents one of the nicest explanations of the role of EBM and what it offers. doi.org/10.1378/chest.08-006…
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Master EBP, AMC-UvA retweeted
Because what patients care about is absolute and not relative effects, it is crucial that systematic reviews provide absolute as well as relative effect estimates. Sadly, they very often don’t. doi.org/10.1016/j.jclinepi.2…
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Master EBP, AMC-UvA retweeted
New slides on some common paradoxes and fallacies in epidemiology covering absence of evidence fallacy, T2 fallacy, winner's curse and Stein's paradox @NorskEpi slideshare.net/MaartenvanSme…
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Master EBP, AMC-UvA retweeted
Helpful and insightful explanation of how predictive values change when prevalence changes. But beware - it is not certain that sensitivity and specificity remain unchanged. In theory they do, but in reality different prevalence may correspond with a different patient spectrum/
Sensitivity, specificity, positive predictive value, and negative predictive value can be tricky! See 4-slide thread below to learn the basics!! The key is understanding that prevalence of Dz significantly affects PPV and NPV, while sensitivity and specificity remain unchanged.
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Master EBP, AMC-UvA retweeted
I’ve spoken recently about how EBM teaching should move away from risk of bias/methods to understanding overall quality of evidence & results. Latest a 10 minute exposition for a meeting celebrating the 25th anniversary of the Iberoamerican Cochrane Center youtu.be/RfLlPChUlqU
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Master EBP, AMC-UvA retweeted
Have we opened a ‘Pandora’s Box’ of Systematic Review types? We discuss this (and more) in our recent ⁦@BMJ_EBM⁩ paper 👇 ebm.bmj.com/content/early/20…
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Master EBP, AMC-UvA retweeted
The Journal Observational Studies has just published interviews with 4 causal inference contributors, Don Rubin, Jamie Robins, James Heckman, and humble me. Here's a link to my interview: muse.jhu.edu/article/867087/… The other 3 can be found via Obs. Studies. Ian Schrier is moderating
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Master EBP, AMC-UvA retweeted
ScHARRHEDS: RT @CTRU_Sheffield: The DIAMOND Study are hosting a free course on the design and analysis of n-of-1 trials for non-statisticians on 26th October. This will be delivered by Professor Stephen Senn @stephensenn, renowned expert in n-of-1 trials… forms.gle/ES4m4kpAMjJ4FbUH8
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Confused about discrimination and calibration? Lead author of our JAMA Users’ Guide summarizes these key concepts for prediction models in an interview with a well-informed interviewer – yours truly. edhub.ama-assn.org/jn-learni…
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Master EBP, AMC-UvA retweeted
If you missed this open access book, don't despair! Download chapters or the whole book here: link.springer.com/book/10.10…
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Master EBP, AMC-UvA retweeted
Is the paper you need stuck behind a paywall? Five websites every researcher should know to access any research paper for free @AcademicChatter @OpenAcademics
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Master EBP, AMC-UvA retweeted
My new mug.
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Master EBP, AMC-UvA retweeted
Heel veel zin om in deze nieuwe positie verder bij te kunnen dragen aan duurzame en innovatieve #GR samen met de kenniskring en samenwerkingspartners.
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Master EBP, AMC-UvA retweeted
This is wonderful @xkcd
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