Mats Nilsson lab at @Stockholm_Uni, part of @SciLifeLab, researching molecular diagnostics and in situ spatial transcriptomics 🔬🧬 🧫🔧
Joined August 2019
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We're now also on Bluesky, sharing news from our lab. Follow us at the following handle! (nilssonlab.org)
MatsNilssonLab retweeted
Open-source, high-throughput targeted in situ transcriptomics for developmental and tissue biology
Read this Techniques & Resources Article by Hower Lee @lee_hower, Marco Grillo, Mats Nilsson @MatsNilssonLab @scilifelab & colleagues:
journals.biologists.com/dev/…
ALT Figure 1: Open-source, high-throughput targeted in situ transcriptomics.
More news!
🚀 New research led by Maria Escrivà Conde & Axel Andersson from @CarolinaWahlby's lab , uncovers the cellular diversity and zonation patterns within the desmoplastic rim in #Colorectal #LiverMetastasis using #ISS 🔬💡 #CancerResearch
aacrjournals.org/clincancerr…
Many thanks to @CarolinaWahlby, Hanna Nyström and Peter Vermeulen for such a nice collaborative effort!🔎👩🔬
🎉 Exciting news! Our latest work is now published in @Dev_journal!
The open-source solution for RNA-targeted in situ sequencing provides an accessible and efficient method for spatially resolved gene expression analysis and spatial multi-omics.
🔗 doi.org/10.1242/dev.202448
🔎Interneuronal divesity in the human striatum uncovered!🧠 We are glad to contribute to the spatially-resolved characterization of striatum in an effort lead by @AMunozManchado and her team👩🔬 #spatialbiology #xenium
Very glad to share our story on striatal human interneurons! Huge thanks for the great time that made it possible! nature.com/articles/s41467-0… @INiBICA_IIS @univcadiz @karolinskainst @NatureComms @SEBBM_es @SENC_
New preprint alert! Work led by @PhyloBrain with contribution from our lab out in Biorxiv!
NEW AVIAN BRAIN ALERT!
Check our research on the development of the pallium in birds🐣 and reptiles🦎. Comparative neurogenesis, scRNAseq and spatial-omics showing that the pallium of amniotes develops in different ways, but converge into similar circuits! shorturl.at/bvFJL
MatsNilssonLab retweeted
Workshop alert: Together w @GioeleLaManno we organize on April 29 a 1day onsite event at EPFL about computational imaging based ST feat @CarolinaWahlby, @MatsNilssonLab & local ppl @epflSV @EPFL_Imaging . epfl.ch/labs/weigert-lab/com…
🚨 Our work on the cellular dynamics of lesion development in mouse experimental autoimmune encephalomyelitis (EAE) and human postmortem samples, now out in @CellCellPress!
Fantastic collaboration effort spearheaded by @chrislangseth and @PKukanja!
cell.com/cell/fulltext/S0092… .. 1/N
And of course, none of this could be possible without the fantastic collaboration between the labs and the in situ sequencing facility @MatsNilssonLab & @GoCasteloBranco @karolinskainst @Stockholm_Uni @scilifelab
Congrats and great job to everyone involved!
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Glad to see technologies pioneered in the lab now accessible to the wider scientific community 🫡🤝
#spatialbiology #padlockprobes
Dr. Mats Nilsson has spent his career developing new #spatialbiology and #singlecellspatial tools to break through technological limitations. See what he and Dr. Katarina Tiklova had to say about Xenium #InSitu and the past, present, and future of spatial! 10xgenomics.com/blog/dr-mats…
🚨Job Alert🚨
Our Staff Scientist position at @sangerinstitute is now up and running. Do not hesitate.
Apply today: sanger.wd3.myworkdayjobs.com…
LinkedIn: linkedin.com/jobs/view/37773…
🚨New preprint🚨
Who says spatially resolved transcriptomics solutions need to be extremely expensive 😤? We say, it does not have to be *that* complicated nor expensive.
biorxiv.org/content/10.1101/…
@lee_hower @chrislangseth @sergiomarco96 @Marcoooooooooo
This is our humble attempt to democratize in situ transcriptomics for the masses. Here in this preprint, we @MatsNilssonLab have put together an end to end solution for targeted in situ transcriptomics that is compatible with immunostaining and other labelling methods. ... 1/N
🚨Looking to learn more about cutting edge spatial technologies?🚨
Join the #InSituSequencing Unit @scilifelab and @10xGenomics at Biomedicum on 11th May, 10am, introducing the new high performance Xenium spatial platform!
Registration link 👇
scilifelab.se/event/start-di…
Thrilled to share our latest collab publication in @natureneuro
Congrats to Xiaofei Li, @chrislangseth @lee_hower @dgyllborg and collaborators @adameykolab @slinnarsson @joalunatkthse Erik Sundström @HDCA_Sweden @scilifelab
nature.com/articles/s41593-0…
🔬 LAB MANAGER WANTED 🔬
The Nilsson Lab at @scilifelab & @Stockholms_univ is seeking a talented Lab Manager to join our diverse and international team! 💻🧪
Apply now: su.se/english/about-the-univ…
In Situ Technology has come full circle!
Originally pioneered and developed in the Nilsson lab, in situ analysis / sequencing has come home in the form of two Xenium In Situ platforms from @10xGenomics.
Xenium will be offered as a service by Spatial Omics platform @scilifelab
MatsNilssonLab retweeted
Interested in the #Xenium In Situ platform from @10xGenomics? We've evaluated data quality, defined best practices and complementary open source tools to enhance its analysis. We also compared Xenium to other spatial transcriptomics platforms. #spatialbiology
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Optimizing Xenium In Situ data utility by quality assessment and best practice analysis workflows biorxiv.org/cgi/content/shor… #bioRxiv
Out in @NatureCellBio!
In collab with Samakovlis lab, @ASountoulidis & @sergiomarco96 built a #spatiotemporal atlas of the human embryonic lung. Novel cell types, differentiation trajectories & interactions identified. Want to know more?
See #Thread 1/N
nature.com/articles/s41556-0…
These are some of our finding, but there is more biology in our data. For exploring our data, we put together a #Tissuumaps viewer with all the data. It's fast, interactive and easy to use. 9/N
tissuumaps.dckube.scilifelab…
Finally, congrats to @ASountoulidis and @sergiomarco96 for leading this @HDCA_Sweden effort and to the labs involved, including Samakovlis, @slinnarsson @joalunatkthse @Prof_Lundberg @CarolinaWahlby @jakmic2003 and Erik Sundström's lab.