human cardiogenesis | congenital heart defects self-organization | bridge molecules-cells-tissues training a new generation of scientists
IMBA, Vienna, Austria
Joined July 2017
- Tweets406
- Following208
- Followers1K
- Likes331
Pinned Tweet
I am really happy to share a new preprint from our lab on cardiac repair! To dissect how immune-ECM-cardiomyocyte interactions lead to cardiac repair, we established a modular human cardioid injury platform.
biorxiv.org/content/10.64898…
MendjanLab retweeted
Force regulation of myogenesis by Tono, a BTB-Zn finger transcriptional regulator, which forms droplets after acute high pressure application. It responds in 1 minute :) - in yellow in the nuclei sciencedirect.com/science/ar…
Congrats to Xu Zhang and @JrmAvellaneda #Drosophila #muscle
MendjanLab retweeted
Beyond thrilled to present our first (!) work @TheCrick! A tour de force by @tobyandrews et al combining imaging, solid morphometrics, theory, perturbations to show how a developing heart grows and scales up its morphological complexity to keep beating...
biorxiv.org/content/10.1101/…
Pumped to share our latest and first (!) work from @_Priya_R lab @TheCrick! Using the powers of #zebrafish, we uncover how multiscale mechanochemical coupling drives morphological and functional maturation of the developing heart 🫀
Stay tuned for the🧵
biorxiv.org/content/10.1101/…
MendjanLab retweeted
Very excited to see our new paper online @Nature, where @justuskleifeld @Patricia_Rothe_ and myself decipher the molecular choreography for how disassembly of the spliceosome begins. This was a great collaboration between the @plaschka_lab and @LCochella lab @IMPvienna.
MendjanLab retweeted
'The Mechanics of building functional organs - our take on this fundamental problem. We discuss general design rules building complex 3D geometries, advocate for a holistic understanding of morphogenesis by embracing the complexity of embryonic development.cshperspectives.cshlp.org/co…
How do embryos build organs with the right shape, size and function to keep our bodies ticking?🫀🫁👀
@_Priya_R and I give our take here, in a rollercoaster ride from local cell behaviors to organ-scale physiology and back
cshperspectives.cshlp.org/co…
MendjanLab retweeted
Congratulations to Clara Schmidt, @MendjanLab, who successfully defended her PhD thesis titled “Multi-Chamber Cardioids Unravel Human Heart Development and Cardiac Defects!”
MendjanLab retweeted
Meet EcoBot the professional weeder.
The Machine Learning, Solar powered apparatus that can run for the entire day pulling weeds.
Replaces expensive in every possible way, herbicides.
MendjanLab retweeted
Elly Tanaka will be IMBA’s new Scientific Director, heading the institute from April 2024 onwards. Elly Tanaka is a renowned researcher, who studies the regeneration of complex body parts. Welcome, Elly!
MendjanLab retweeted
New manuscript alert! Writing in @Nature, the Burga Lab (@arburga) describe a genomic silencing mechanism which represses a selfish genetic element in the eggs of the nematode C.tropicalis only when it is paternally inherited. Their findings reveal the potential evolutionary origin of genomic imprinting.
oeaw.ac.at/imba/research-hig…
MendjanLab retweeted
Our paper describing Bioframe, a python library for working with genomic intervals, was just accepted! academic.oup.com/bioinformat…
Check out bioframe (biorxiv.org/content/10.1101/…), a library for working with genomic interval #dataframes in #python and #pandas!!
MendjanLab retweeted
What a beautiful sight - children with Microscopes, curiosity in their eyes learning the wonders of Developmental Biology! Terrific outreach event organised by @InSDB_79 and fantastic students at @NCBS_Bangalore. Great start to InSDB 2024!
MendjanLab retweeted
Our new data-driven mathematical model of sarcomere assembly is now out. All the math was done by our fantastic collaborators in Dresden @friedrich_group @PoLDresden @IBDMmarseille @ClaraMSidor @BDehapiot journals.aps.org/prxlife/pdf…
MendjanLab retweeted
What graduate degree should you go for? The MBA, the MD, the JD, or the PhD? The PhD is unique - it has to be said - for teaching both critical reasoning and the creative process of discovery; skills that prepare you for anything you’d then want to do.
MendjanLab retweeted
Our latest release on placental microvasculature..Just in time for the holidays! @LabHaase science.org/doi/10.1126/scia…
MendjanLab retweeted
One decade after starting this journey, our collaborative paper with @Gibson_lab is finally out: rdcu.be/dtupS.
It reports chromosome assemblies of the related sea anemones @Nematostella and Scolanthus callimorphus. Will be an important resource for the community.
MendjanLab retweeted
Is there a better way to make PGCs in culture than with disorganised EBs and signalling cocktails? In our latest pub @Dev_journal we show that mouse 'gastruloids' make beautiful PGCs... 😍 [as also seen by others] (1/6) doi.org/10.1242/dev.201790
MendjanLab retweeted
Why do we get certain diseases whereas others do not exist?
This new book builds a foundation for systems medicine. Starting from basic laws, it derives why hormone, immune and aging circuits are built the way the are, culminating in a periodic table of diseases.
MendjanLab retweeted
Great study in @CellCellPress from our virologist colleagues @puchhammer et al & neurologists of the @MedUni_Wien. Bravo!! 👏
Specific Epstein-Barr virus determinants and immune responses by NK & T cells implicated in the risk for #multiplesclerosis.
cell.com/cell/fulltext/S0092…
MendjanLab retweeted
Cannot recommend this enough!
