Pathology and computational biology through engineering and applied physics

Stanford, CA
Joined September 2018
Michael Angelo retweeted
I am deeply honored to be named by the Stanford Medicine Alumni Association this year for the “Arthur Kornberg and Paul Berg Lifetime Achievement Award in Biomedical Sciences.” As a Stanford graduate student in the 1980s, I took a remarkable class in plasmid and phage replication from Dr. Kornberg. I marveled at his incisive manner of teaching complex concepts in science. I learned fundamentals of retroviral gene transfer from postdoctoral fellows and technical staff in Dr. Berg’s laboratory. I was in constant awe of Dr. Berg’s statesmanship on the world stage as a spokesman for science. Arthur Kornberg, M.D. and Paul Berg, Ph.D. were luminaries long before I was a graduate student. Professor Kornberg won the Nobel in Physiology or Medicine for isolating DNA polymerase and demonstrating how it could replicate DNA in a test tube. Professor Berg won the Nobel in Chemistry by showing the first inter-species DNA hybrid of bacterial and eukaryotic viral DNA and replicating it in bacteria. Professor Berg was instrumental in pointing out the dilemmas around recombinant DNA at the foundational Asilomar Conference in 1975, a critical meeting focusing on the ethical uses of rec-DNA technology. Dr. Kornberg’s and Dr. Berg’s efforts deeply touched biomedical sciences and helped patients worldwide. They symbolized science's dual role in fundamental discovery and service to humanity.
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SCI member @MikeAngeloLab discusses how the emerging field of #SpatialBiology will help scientists gain an in-depth understanding of the #TumorMicroenvironment and better predict patient outcomes. stan.md/4cQTB3f
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Michael Angelo retweeted
In a post #AlphaFold world, we can use protein structures in ways we never could before. Can we build phylogenies with them? Are they any good? Yes! Foldtree (biorxiv.org/content/10.1101/…) surpasses traditional sequence-based methods, even for closely related proteins.👇
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This beaver was orphaned and rescued as a newborn, Watch the incredible instinct to build a dam, even though it’s never seen its parents build one..
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Michael Angelo retweeted
I can’t get enough of these puns…and also the amazing opportunity to do science and explore the cellular jungle of tissues!
Are you feeling offal? Then take a minute to digest the inner workings of your intestine with this CODEX image by Dr. @JohnHickey22 from @GarryPNolan lab @stanford. We've got a gut feeling about this! #CeliacDiseaseAwarenessDay #CeliacDisease
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Michael Angelo retweeted
Preprint! This is definitely the most innovative and creative technological project that I have worked on: Escalating High-dimensional Imaging using Combinatorial Channel Multiplexing and Deep Learning. biorxiv.org/cgi/content/shor… 🧵👇
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Michael Angelo retweeted
Continuing the serious conversation on UAP. Many thanks to Debrief and Micah Hanks for this steady-handed summation. A lot of people helped get to this point, literally over decades. You know who you are and many know who you were. A lot of people will be required to move it forward. You don't even know you will be helping, but together we will help you realize your hand in this. UAP are, as I call it, a Zen question-- no matter the form of the question the answer will be fascinating. thedebrief.org/the-sol-found…
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Michael Angelo retweeted
While these definitions are extremely 👀, their implications are implicit. However, in Sec. 9002 the Senate explicitly “finds & declares” why this UAP Disclosure Act “legislation is necessary.” They state 5 points that everyone (especially reporters) should closely examine:👇🧵
Factcheck: The term "non-human technology" never appears in the National Defense Authorization Act passed by the U.S. Senate on 7-27-23. But the term "technologies of unknown origin" appears 13 times, and the term "non-human intelligence" appears 18 times. douglasjohnson.ghost.io/uap-…
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Michael Angelo retweeted
This has been one of those true “it takes a village” studies that has been ongoing for >7 years. It took a long time to reconcile the knowledge base around human #Hematopoietic progenitors and dive even deeper to show something new. Millions of #singlecells so many #HSPCs
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Give it.. 😂
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Michael Angelo retweeted
How often does the US launch to intercept UAP? Has this number changed after the recent balloon shoot downs?
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What does a GI oncologist get his wife for her 45th birthday? A screening colonoscopy! (Follow me for more pro tips on thoughtful gifts and keeping the magic alive in your marriage)
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See the full HuBMAP collection here: nature.com/collections/aihih…
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Michael Angelo retweeted
At UFO hearing, some in Congress made accusations that Defense Contractors are keeping/reverse-engineering UFOs. We decided to ask a few. Lockheed Martin responded. Their short response was not a denial: “Questions about UAPs are best addressed by the U.S. government."
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Michael Angelo retweeted
Smart people are mocking the idea that the U.S. government is hiding alien spaceships and bodies. They're wrong. I've researched this issue for years: there is credible evidence the secret UFO program is real.🧵 1/N
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Michael Angelo retweeted
Stanford Medicine
@StanfordMed28 Jul 2023
Understanding how placenta grows into the uterine wall could help scientists understand what goes wrong in pregnancy complications such as placenta accreta, preeclampsia, and miscarriages. #Pregnancy #MedTwitter stan.md/3DiSI3F
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