Husband, father, Assistant Scientist at Henry Ford Hospital interested in metabolic research. Tweets are my own.
Detroit - Windsor
Joined August 2019
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We have the lab up and running! Looking to recruit a post-doc to join us in the “D”. Applicants interested in metabolic disease research with an inkling towards using imaging approaches to study lipid metabolism. henryford.com/physician-dire… DM @Mottillo_Lab Please RT. Thanks!
Emilio Mottillo retweeted
The tragic transition of 🇨🇦 from fighting alongside 🇺🇸 in 2 world wars and in Afghanistan, rescuing American hostages in Iran, working collaboratively with our American neighbours across a spectrum of endeavours, now waking up with sadness to a new economic declaration of war 💔
Our JBC paper is now online! Here we examine the mechanisms by which a common genetic variant in PNPLA3 (148M) causes fatty liver disease and builds upon our previous work on the interaction of PNPLA3 with ABHD5.
jbc.org/article/S0021-9258(2…
Targeting of ABHD5 to LDs is also required to promote the interaction with PNPLA3. So both proteins need to be on LD!
New study from @Z_GerhartHines lab identifying a novel pathway regulating food intake and energy expenditure
nature.com/articles/s41586-0…
Had a great time in Munich at the Helmholtz Diabetes conference. It was an honor to be nominated for the HeIDi Young Investigator award and present our work. Wonderful meeting all the new people and connecting again with colleagues!
t1p.de/4qbhh
Emilio Mottillo retweeted
Let the games begin! 🎉
The 11th Helmholtz Diabetes Conference has officially begun! Stephan Herzig just opened the event, and we’re very excited for the next 3 days full of cutting-edge research focusing on wasting metabolism! 🙌
#HelmholtzDiabetes2024
Our paper is now online! Here we investigate the direct effect of lipolysis on AMPK signaling in adipocytes. Using our real-time FRET sensor we show lipolysis genereates long-chain acyl-CoAs that are involved in allosteric activation of AMPK.#lipidtime
rdcu.be/duWEg
New work from S. O'Rahilly's group shows GDF15 drives nausea and vomiting duirng pregnancy. Interesting study! rdcu.be/dtyNf
Happy to share my promotion to Associate Professor of Physiology at Wayne State University @waynestate
Great job by graduate student in my lab Andrew Butcko presenting at the @nih_nhlbi T32 Training grant retreat
Trainees (prior and current) presenting at the 2023 Detroit Cardiovascular Training Program (NIH T32) #NIH #NHLBI retreat at #WSU #timbryson
ALT Detroit Cardiovascular Training Program sponsored by NIH NHLBI
Emilio Mottillo retweeted
Preprint alert! We are happy to introduce Contact-FP, a suite of probes for studying #MembraneContactSite dynamics. This was an amazing team effort led by Research Associate @GregoryMiner18 and postbacc Sidney Smith 1/11 biorxiv.org/content/10.1101/…
Interesting new work showing serotonin as a suppressor of human BAT. The authors propose this may explain weight gain associated with SSRIs. The serotonin transporter sustains human brown adipose tissue thermogenesis | Nature Metabolism nature.com/articles/s42255-0…
New works shows that ABHD5 (CGI58) controls placental lipid metabolism indepdent of ATGL (PNPLA2). ABHD5 also interacts with PNPLA9 adding to the list of PNPLA binding partners.
JCI Insight - The lipase cofactor CGI58 controls placental lipolysis insight.jci.org/articles/vie…
Emilio Mottillo retweeted
Jennifer Lippincott-Schwartz, PhD @JLS_Lab will be delivering the Closing Kern Lecture at this years conference. She'll be presenting on “Imaging Interacting Organelles to Understand Metabolic Homeostasis”. @EbruErbayLab @AranyLab @DrMorganLevine
New work showing the Kidney in an axis to mediate the anorexic effects of metformin/GDF15. Renalkines anyone?
cell.com/cell-metabolism/ful…
Emilio Mottillo retweeted
Very exciting 2024 @FASEBorg Lipid Droplet Conference in the works, co-organized by @OlzmannLab and us. Stay tuned for more details!
Mark your calendars! The @FASEBorg Lipid Droplet Conference will be next summer July 21-25 2024 in St Paul MN at the Intercontinental Hotel! Beautiful venue and an amazing lineup of speakers! Co-organizing with @HenneLab. Website with more info coming soon. #LDSRC24 #LipidDroplet
ALT FASEB Lipid Droplet conference. Mark your calendars! July 21-25 2024.