MRC funded collaborative research study investigating the causal role of innate immunity in psychosis: aiming to develop new targeted treatment options

Joined December 2019
Excited about welcoming colleagues to Bristol tomorrow for our ⁦@The_MRC⁩ Psychosis Immune Mechanism Stratified Medicine (PIMS) Collaboration ⁦annual meeting. Guest lecture from Prof ⁦⁦@MondelliValeria⁩ ⁦@RachelUTG⁩ ⁦@MrcPims⁩ are you ready?
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PIMS study open and running- first participant randomised! @IMH_UoB @TheCHBH @uhbtrust @BWC_NHS
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Thrilled to see Fabi @_Fabi_CZ presenting a fantastic topic today on the role of immune regulation in psychosis and mental health @MIDASUoB excited to be part of this work @MrcPims
Almost a year has passed (too fast!) first time presenting some of flow protocol for @MrcPims 🥹🤪😮‍💨🤩 - and last conference of the year for me before going back 🇬🇧 ✈️ 🇧🇷 thanks so much @UoB_SoP @Primed_UoB @AgenciaFAPESP @usprp #MOIS22 🩸🧫🔬👩🏻‍🔬🤞🏼
Replying to @golam_khandaker
@golam_khandaker discusses temporality, comorbidity, and confounding in #psychosis and #depression, stressing the importance of patient stratification in future #immunotherapy trials. Join the discussion this afternoon at my poster (G12) 🗣️ #BAP2022 @BAPsych @mrc_ieu @MrcPims
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At the ⁦@BAPsych⁩ conference? Don’t miss our symposium on novel immunological mechanisms and treatment options for schizophrenia 26th July 9-11.30 With ⁦@bdeako⁩ ⁦@RachelUTG⁩ ⁦@GaryD2011⁩ and Rebecca Woods
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⁦!! job alert 👇 👇with the amazing @MrcPims⁩ team- Research Fellow- PIMS trial immunophenotying - me and Prof Nick Barnes #flow #iMDM 🧫🧫 bham.taleo.net/careersection…
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With @golam_khandaker @bdeako @ProfTonyDavid and the PIMS team!
Study used Mendelian randomization and brain atlas data to demonstrate that IL6/IL6R may have a specific, causal relationship with brain structure, relevant for #schizophrenia and other disorders. ja.ma/3qPKbzb @RachelUTG @johnn33dscoffee @stevesphd @MrcPims
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Delighted to share our @MrcPims study showing potential causal effect of inflammation on brain structures relevant for several psychiatric & neurodevelopmental disorders 👇 With @RachelUTG @bdeako @ProfTonyDavid @stevesphd et al 🙏 @The_MRC #PIMScollab ja.ma/35nsbEL
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Job alert 🚨 We are hiring a Research Assistant for the #Cambridge site of our multi-centre clinical trial of immunotherapy in first episode psychosis 👇 Application closes 22nd Dec! @psychiatry_ucam @CPFT_Research @MrcPims @Cambridge_Uni jobs.cam.ac.uk/job/32511/
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Excited to be giving two talks today on transdiagnostic neuro-clustering at @conference_2021 at 09:45 am BST and at @ECSR__berlin at 10:20 am BST. Do tune in if you're attending either conference! #transdiagnostic2021 #ECSRBerlin2021 #AcademicChatter @AcademicChatter #phdchat
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Ten key disease-agnostic #research questions that, if addressed, could lead to significant #progress within #neuroimmunology in the short to medium term 👇 Research priorities for neuroimmunology. MacKenzie G et al. @WellcomeOpenRes wellcomeopenresearch.org/art…
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On 6th July we had our 2nd virtual away day where we had a fantastic line up of ECR talks. To find out more, you can access our latest PIMS blog here ⏬ birmingham.ac.uk/research/me… @MrcPims @IMH_UoB
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Our PhD Student, Alex Murray's, selective review of role of inflammation in psychosis @InstituteMH @UoNresearch @ResearchNotts @NottsHealthcare
Great to see this out! Fantastic work from the twitter-less Alex Murray. No doubt the first of many. With Peter Liddle, Zia Katshu and @RachelUTG #proudsupervisor
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We conclude the day with fantastic talks on cell and animal models, imaging, and population samples! Thanks @EdPalmer5, Connor Dunleavey, Alex Murray @IMH_UoB and Rebecca Woods (Manchester) Thanks to all presenters and those who dialled in!
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@MrcPims experimental medicine study looking set for study recruitment later on this year @golam_khandaker @eimear_foley1
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Our very own @MrcPims post doc Andrey Barskey talks about unpacking the black box of ML, and applying generative deep learning to explicitly model structural brain differences and their relationships with key biomarkers.
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Great example of @orygen_aus and @IMH_UoB collaborations demonstrated by stellar PhD students @P_Lalousis and @herniman_sarah! Fantastic work using ML and network modelling to map psychosis symptoms and inflammation.
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The 2nd PIMS virtual away day is about to kick-off! We have a fantastic line-up of ECR talks throughout the morning! First up is @benjmnperry presenting his work on 'Inflammation as a cause of insulin resistance in schizophrenia' @IMH_UoB @RachelUTG @golam_khandaker
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On #Worldschizophreniaday2021 retweet of our Blog from Dec 2019.. so much work done since then, so much more to do!@golam_khandaker @bdeako @lowrigriffiths_ @P_Lalousis @ParianteSPILab and all!
The final blog of 2019 is up NOW on InSPIre the Mind!✍️ This week, @RachelUTG introduces us to the recently launched PIMS Study - investigating how the immune system may be related to #psychosis so that new & better #treatment strategies can be developed medium.com/inspire-the-mind/…