Samuel Mackenzie MD PhD (@NotoriousEMG) header
Samuel Mackenzie MD PhD (@NotoriousEMG) profile picture

Pediatric #neuromuscular doc, amateur scientist @URneuroscience, runner, chess enthusiast, dad. #Meliora

Rochester, NY
Joined September 2021
Photo by Samuel Mackenzie MD PhD (@NotoriousEMG)Photo by Samuel Mackenzie MD PhD (@NotoriousEMG)Photo by Samuel Mackenzie MD PhD (@NotoriousEMG)Photo by Samuel Mackenzie MD PhD (@NotoriousEMG)Photo by Samuel Mackenzie MD PhD (@NotoriousEMG)Photo by Samuel Mackenzie MD PhD (@NotoriousEMG)Photo by Samuel Mackenzie MD PhD (@NotoriousEMG)Photo by Samuel Mackenzie MD PhD (@NotoriousEMG)Photo by Samuel Mackenzie MD PhD (@NotoriousEMG)
Samuel Mackenzie MD PhD retweeted
Dr. Annie Andrews Dr. Amy Acton Dr. Adam Hamawy Dr. Abdul El-Sayed ♥️
16
310
18
3,939
29,937
Samuel Mackenzie MD PhD retweeted
CNN PROJECTS THAT THE MITOCHONDRIA WILL REMAIN THE POWERHOUSE OF THE CELL
178
5,876
215
54,566
1,101,615
Samuel Mackenzie MD PhD retweeted
Lebron signing with the sixers really changed the direction of this country
94
4,165
206
35,097
862,283
Samuel Mackenzie MD PhD retweeted
Every journal editor's inbox right now. Generative AI has turned systematic and scoping reviews into a mass-manufacturing assembly line. We’ve gone from rigorous evidence synthesis answering clinical dilemmas to synthetic meta-narratives built around questions nobody asked, answering problems that don't exist. Publishers love them because every automated "systematic review" brings a $ APC with zero lab auditing overhead. Citation cartels love them because reviews are lazy citation magnets that inflate Impact Factors without doing a single day of actual benchwork. The system isn't broken; it is functioning exactly as commercial publishing designed it: monetize volume, reward citation churn, and leave editors to shovel the algorithmic sand! 🚜📈💵 #MotorShastra #AcademicPublishing #ImpactFactor #APC #PeerReview #GoodhartsLaw
As an Editor, in past ~6mo, we are receiving an avalanche of unsolicited review articles (“scoping” “systematic”, narrative, NOS) on topics and ?s NO ONE EVER has asked and clearly with heavy AI lift. Even the cover letters all read the same…alarming and sad. #publishing
3
26
4,211
Samuel Mackenzie MD PhD retweeted
🎉 Congratulations to Training Director Awardee Rachel Gottlieb-Smith, MD, MHPE! #CNSAM
1
1
4
217
Samuel Mackenzie MD PhD retweeted
As an Editor, in past ~6mo, we are receiving an avalanche of unsolicited review articles (“scoping” “systematic”, narrative, NOS) on topics and ?s NO ONE EVER has asked and clearly with heavy AI lift. Even the cover letters all read the same…alarming and sad. #publishing
17
25
11
163
38,072
This was a good time. I played the role of Curious George.
🧬 Thrilled by the incredible success of our CNS Genetics Summit 2026! Our third year bringing together expertise in medical education and genomics, with a shared vision of making genetic testing part of everyday clinical practice.
4
170
If you’ve listened to Immature Brains, you’d already know all this stuff, but if you haven’t, you can learn about the history of med ed in child neurology at #CNSAM @OligoclonalBand
2
1
5
312
I wasn’t the one who f’d up the sound to be clear.
1
2
310
Samuel Mackenzie MD PhD retweeted
The August episode of Immature Brains: A Child Neurology Podcast is live! Near and dear to our hearts - and important to all neurologists: Transitions of care from child to adult neurology rss.com/podcasts/immature-br… 1/
1
3
1
15
1,155
We’re back, baby!
I started listening to this again today (to check the sound, and then I got sucked in) and honestly I think it's one of our best podcasts. Interested in neurodevelopmental disabilities and how we care for the whole patient? Take a listen!
1
4
867
Samuel Mackenzie MD PhD retweeted
Esta es la mejor manera de ver el mundial!
1,781
21,175
1,770
182,841
7,150,392
Samuel Mackenzie MD PhD retweeted
I enjoy using IGV, but I need a more efficient tool for analyzing diploid genomes. So, I developed one for myself. It provides exceptional GPU acceleration, allowing me to uncover all essential information spanning six orders of magnitude. #bioinformatics #genomics #visualization
13
52
337
25,115
Samuel Mackenzie MD PhD retweeted
Replying to @ATinyGreenCell
Tryptophan is the tenured senior professor of amino acids. It negotiated a private parking spot, its own codon, and then spent the entire department budget on synthesizing serotonin.
5
7
2
125
3,358
This is wild. Smells like a class action lawsuit to me.
Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact ThermoFisher has systematically manipulated antibody validation data. Short Thread... 🧵
1
206
Samuel Mackenzie MD PhD retweeted
Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures", but their own internal data.
42
234
78
1,066
264,363
This is my favorite scene from The Bible.
1,081
11,316
598
85,590
1,534,047