@OffirU

MD | Gastroenterology Fellow at Sheba Medical Center | IBD research and innovations. #IBD #Gastroenterology #Research

Joined March 2020
  • Tweets13
  • Following59
  • Followers21
Offir Ukashi retweeted
Shomron Ben-Horin@ShomronHOct 26
Is proximal small bowel Crohn worse than distal bcs the Tx is less effective there? Well, No... In our @sheba_medical #capsule study now published in @AGA_CGH , biologics induced similar mucosal healing in proximal vs distal SB. @OffirU @HelmsleyTrust cghjournal.org/article/S1542…
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Offir Ukashi retweeted
Shomron Ben-Horin@ShomronHJun 15
A study by our Drs Tal Engel and @OffirU in @AmJGastro shows that assessment of the same stool consistency by Bristol stool scale is inherently different between IBS pts and doctors. Better objective tools and candid communication are needed. share.google/TkdZ4oxOKR84RMD…
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איפה רוני קובן? הנה ד"ר לימור גולדנברג מבנימינה שהלל יפה הודיעו הבוקר שמונתה למנהלת פנימית ב': היא בוגרת הטכניון ומומחית ברפואה פנימית ובפרמקולוגיה קלינית, וגם... בוגרת הנדסת חשמל בטכניון, ואפילו בהצטיינות. @TechnionLive @WallaNews @HILLEL
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Offir Ukashi retweeted
UEGJ@UEGJournal21 Nov 2025
🧭 #Vedolizumab promotes small-bowel and pan-enteric #healing in #CrohnsDisease 🔸PE-mucosal healing: 15.9% at week 52 🔸SB-healing: 4.5% → 18.2% 🔸Clear reductions in CRP, FCP, Lewis & Eliakim scores 🔸Well tolerated 📖 #OpenAccess 👉bit.ly/43DZNt4 @my_ueg
Visual Abstract

ALT Visual Abstract

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Replying to @JeanFredericCo1 @IBDimmunology @TheLancet
Definition of relapse was rather non-standard, and rate of steroid Tx for relapse comparable between arms, as discussed in our Editorial thelancet.com/journals/langa…

Appendicectomy: a novel treatment for ulcerative colitis?

Although the appendix is generally believed to be a vestigial organ, there is growing evidence pointing to its possible role in modulating gut immunity and microbial homoeostasis.1,2 These roles have...

thelancet.com
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Our RCT now in @AGA_Gastro : Pts with #Crohn in remission, who recieved treat-to-target Tx guided by #capsule endoscopy inflammatory assessment, had a significantly lower flare risk over 24m compared to pts continuing standard care @HelmsleyTrust gastrojournal.org/article/S0…
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Hot off the press. Inter‐Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five‐Nations Survey Study. @UriKopylov @FernandoMagro6 #henityanai ⁦@OffirU⁩ #5Nationfriendsandparticipants onlinelibrary.wiley.com/doi/…

Inter‐Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five‐N...

Background The Montreal classification has been widely used in Crohn's disease since 2005 to categorize patients by the age of onset (A), disease location (L), behavior (B), and upper gastrointesti...

onlinelibrary.wiley.com
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Offir Ukashi retweeted
Luis Menchén@lamv5018 Jan 2025
Inter‐Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five‐Nations Survey Study. @OffirU onlinelibrary.wiley.com/doi/…

Inter‐Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five‐N...

Background The Montreal classification has been widely used in Crohn's disease since 2005 to categorize patients by the age of onset (A), disease location (L), behavior (B), and upper gastrointesti...

onlinelibrary.wiley.com
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Study by the 🇮🇪🇪🇦🇵🇹🇮🇱🇨🇵 Five-Nations in @UEGJournal showing that (like most classification systems) actual inter-rater agreement for CD Montreal classification is modest at best. At least LLM and AI models were not much better😉 @UriKopylov @OffirU doi.org/10.1002/ueg2.12757

Inter‐Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five‐N...

Background The Montreal classification has been widely used in Crohn's disease since 2005 to categorize patients by the age of onset (A), disease location (L), behavior (B), and upper gastrointesti...

onlinelibrary.wiley.com
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Our talented @Adam_goldman_ found increased intest perforations with JAKi class. Examined in Rheum pts to reduce confounding by IBD. Caveat of voluntary reporting,but this is how aTNF TB risk was first found, so cant be lightly discarded. @UEGJournal pubmed.ncbi.nlm.nih.gov/3973…

Gastrointestinal Perforations Associated With JAK Inhibitors: A Disproportionality Analysis of the...

In this global pharmacovigilance study, all JAK inhibitors were associated with increased reporting of gastrointestinal perforations compared with bDMARDs in RA patients. Until more data on IBD...

pubmed.ncbi.nlm.nih.gov
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FCP is better for colonic > small bowel (SB) inflammatiin, but how accurate is it in proximal vs. distal SB? Using VCE as gold standard, our @sheba_medical brilliant fellow @OffirU reports in @JCC_IBD a dilutional gradient of calpro along the SB ! pubmed.ncbi.nlm.nih.gov/3912…
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