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Using the immune system to cure disease | YC S21

San Francisco, CA
Joined April 2021
Parallel Bio retweeted
Organoids are so cool. They are tiny 3D tissues that mimic features of human organs. E.g. cardiac organoids beat spontaneously and immune organoids can produce antibody responses. Great post by @annasofialesiv on their potential to transform drug development.
what if the cost of drug development followed the cost curve of mass to orbit? what might it take to flip the success rate of successful trials from 5% to 95% I wrote about organoids and how they might help us tackle the biggest cost center in getting drugs to market.
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Parallel Bio retweeted
what if the cost of drug development followed the cost curve of mass to orbit? what might it take to flip the success rate of successful trials from 5% to 95% I wrote about organoids and how they might help us tackle the biggest cost center in getting drugs to market.
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Parallel Bio retweeted
Parallel Bio Cofounder Robert DiFazio on the AI problem in drug discovery: "What's interesting about AI is it's a very one-sided conversation. Everybody's focused on the frontier models, which are incredibly exciting and powerful, but people forget the other half, which is data. It's the same as with original computers, GIGO, garbage in, garbage out. You could have the world's most powerful computer, but if you're feeding it garbage, that's what comes out." "A potential issue with AI in a lot of areas is that these models are incredibly powerful, and pharma is racing to adopt AI, but they're still training AI on animal data. The issue isn't the models. The issue is that they're still using animals." "So for AI to deliver on its promise in biology, doing all the things people describe, which I think is very much possible, we have to have better data. That's the main goal of the company, to produce accurate and diverse human data at an industrial scale."
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New frontiers #3 - axial.substack.com/p/axial-n… 1. ADCs 2. Cultured meats 3. Phenotypic screening 4. Industrial enzymes 5. Chemokines 6. Building the US-version of WuXi 7. Infectious disease 8. Immunometabolism 9. Fast following in drug development 10. Single-cell sequencing
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The @califesciences Fall FAST 2021 program welcomes six startups from SOCAL, who will receive intensive coaching and advisory services from our network of business experts. Welcome Disati Medical, JUAD NGNE, NanoPharma Solutions, OncoXome, Parallel Bio, and V-Flow Medical.
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Parallel Bio is putting the immune system in a dish to improve drug discovery. The duo founded Parallel Bio in the midst of the COVID-19 pandemic and started developing an immune organoid to fill a significant gap in disease modeling. #LongLA bit.ly/3BMFdWO
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