New, interesting, and exciting research in quantitative genetics. Bringing together medical genetics, agriculture research, and evolutionary biology
Joined November 2013
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#BoG14 Really interesting pop gen talks: estimating human gen time, differentiation of height and BMI in EU, IBD mapping identifies new loci
Following and tweeting from #BoG14 Nice meeting so far - great session on complex traits
Data and theory support the application of quantitative genetic approaches to understand complex traits sciencedirect.com/science/ar…
Tissue specific selection for mitochondrial variants? plosgenetics.org/article/inf… #genetics #genomics
Simulations showing weakly deleterious variants should be common in expanding populations genetics.org/content/195/3/9… #genetics #quantgen
Data and theory show both rare and common variants influence traits, and selection altering the proportions nature.com/ng/journal/vaop/n… #genetics
QuantitativeGenetics retweeted
It's almost exactly 5 years since @bmahersciwriter wrote this on "missing heritability." Holds up pretty well, no? nature.com/news/2008/081105/…
Causal variants for Schizophrenia may be of ancient origin rather than many recently occurring mutations? cell.com/AJHG/fulltext/S0002… #genetics
The effects of many underlying causal variants fro BMI are likely to be small. sciencedirect.com/science/ar… #genetics #genomics #quantgen
Mendelian and common diseases show comorbidity. Causal variants of all frequencies for complex traits? cell.com/abstract/S0092-8674… #genetics
Larger GWAS studies continue to reveal more loci for complex phenotypes. nature.com/ng/journal/v45/n1… #genetics #genomics #quantgen
A constant methylation clock across species? Useful as biomarker for ageing, or in forensics? genomebiology.com/2013/14/10… #genetics #quantgen
QuantitativeGenetics retweeted
Find a gene, slap high-fives around the lab, publish to huzzahs, and then … uh-oh slate.com/articles/health_an… #genomics #genetics
QuantitativeGenetics retweeted
Peer into #ASHG2013, the Twitter hashtag for last week’s meeting of the American Society of Human Genetics bit.ly/18whsgk #genomics
QuantitativeGenetics retweeted
Genomics England Will Sequence 100,000 National Health Service Patients to Improve Clinical Care zite.to/17iSIMM #genomics
