Immune Regulation and Tumour Immunotherapy Group led by @squezadd, based at the Cancer Institute of University College of London, UCL.
London, England
Joined September 2018
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linkedin.com/posts/quezada-l…. Come joint our lab Quezada Lab UCL Cancer Institute Cancer Research UK (CRUK) Cancer Research UK (CRUK) City of London Centre Great PhD opportunity to develop advanced immunotherapies against cancer
Congrats to Aurélien Marabelle’s team — intratumoural anti-CTLA-4 links Treg reduction with FcγR⁺ myeloid context, underscoring the FcγR landscape as a key determinant of CPI activity and translation. nature.com/articles/s41586-0…
Quezada Lab retweeted
Congratulations to @CharlesSwanton, Mariam Jamal-Hanjani and colleagues on their fascinating analysis of the evolution of lung cancer metastasis published in @Nature!
nature.com/articles/s41586-0…
Quezada Lab retweeted
Thrilled to see a new paper led by the outstanding @Brown_lab1, now out in Nature Biotechnology.
We provide mechanistic insights into how mRNA vaccines work. challenging key assumptions and offering new ways to control vaccine activity. (1/3)
Read here: nature.com/articles/s41587-0…
Quezada Lab retweeted
Congrats to PICI researcher Dr. Catherine Wu of @DanaFarber on being part of the @CancerGrand ILLUMINE team, awarded $25M to explore the cancer dark proteome, research that could uncover entirely new targets for cancer treatment. bit.ly/4d1AxSV
Quezada Lab retweeted
Excited to share our new work uncovering a previously unknown mechanism identifying ANKIB1 as the E3 ligase that writes a critical new letter of the ubiquitin code central for immune signalling: K11-linked ubiquitin nature.com/articles/s41556-0…
Come join our team!! linkedin.com/posts/quezada-l…
Quezada Lab retweeted
Huge thanks to the team at UCLH and the UCL Cancer Institute @ucl @uclh @uclcancer, particularly Elise Reese @ekvrees and Louise Ainley, and my mentors Benny Chain @BennyChain, Sergio Quezada @QuezadaLab and Kwee Yong.
Quezada Lab retweeted
Immunology takes center stage again at the #NobelPrize! Congratulations to Mary Brunkow, Fred Ramsdell & Shimon Sakaguchi for uncovering how regulatory T cells maintain immune tolerance—a discovery that transformed our understanding of autoimmunity and cancer immunotherapy
Are you looking for a Clinical Research Training Fellowship? Do you want join our team working in cancer immunology and immunotherapy? Check this great opportunity from @CRUKCOLcentre
colcc.ac.uk/clinical-researc…
and contact our team to discuss our proposed project
Quezada Lab retweeted
Pleased to share our preprint describing a central role for post-transcriptional processes in the response to cancer immunotherapy. Huge amount of work led by Maria Vila de Mucha and @julia_hlond in collaboration with @QuezadaLab and @MartT_babraham 1/8
biorxiv.org/content/10.1101/…
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🧬 Join us Friday 19th Sept for CART Autoimmunity Symposium in Central London 🧬 Guest speakers from Erlangen & Hamburg on latest developments in Lupus, Multiple Sclerosis, & MG. Register in link below & see you there! @uclh @uclcancer hartleytaylor.co.uk/carm-hom…
Quezada Lab retweeted
Depletion of Tregs with a non-IL-2-blocking anti-CD25 enhanced antitumor responses in brain tumors and synergized with anti-PD-1 or a tumor antigen-targeted antibody bit.ly/44nab9T @uclcancer @QuezadaLab #Immunotherapy
Quezada Lab retweeted
CHIP is a common, age-related condition where mutated blood stem cells expand without causing blood disorders. CHIP raises the risk of hematological malignancies, chronic inflammatory diseases (like heart & lung disease), & lung cancer. This manuscript shows that CHIP somatic clones in blood—especially TET2 mutant ones—migrate into tumors, reshape immunity, drive progression, and promote recurrence. The ability of a somatic clonal expansion in the hematopoietic compartment, to regulate malignant progression in another tissue represents a new perspective in cancer biology. #CHIP #LCMS #cancer #biology #AACR25 nejm.org/doi/full/10.1056/NE…
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies: cell.com/immunity/fulltext/S…
Amazing collaboration led by @CR_UK funded @QuezadaLab @galvez_cancino @uclcancer and colleagues!
Quezada Lab retweeted
Happy Post Doc Appreciation Week! Our facilities are used by Post Docs at @uclcancer, @kingsmedicine, @QMBCI and @TheCrick.
We spoke to Alex Simpson in @QuezadaLab at @uclcancer about life as a Post Doc.
linkedin.com/feed/update/urn…
#CelebratePostDocs
Looking fwd to a great conference!!!
Good and Bad CD4 T-cell Help:
Cornelis JM Melief, Sergio Quezada, and Robert D. Schreiber will address this topic in a plenary session at the AACR Special Conference on Tumor Immunology and Immunotherapy (October 18-21, Boston).
bit.ly/4chsUVi
#AACRtii24 @squezadd
