RIOtrial

To find out more about the #RIOtrial, check out short animated video link below. vimeo.com/453629820/31eb42a5… Credits: @HIViBase @AngelinaNamiba @ukcherub @sarahfidler4 @JohnFrater5 Will Everett, Hanna Box

Next up is Simon Collins @HIViBase who we're very privileged to have been part of the study from the very beginning as a community representative, sharing his insights on the importance of the study as well as community impact towards the study.

Prof @JohnFrater5 @NDMOxford completing the laboratory journey of the participants' samples, and how we can analyse virology and immunology data in depth from these samples.

@TTipoe from @NDMOxford explains what happens to the large amounts of blood samples generously donated by #RIOtrial participants.

It's a celebratory #RIOtrial participant feedback meeting today! As Prof @sarahfidler4 explains, recruitment has completed and we are closer to being able to report the first findings of the study by early next year.

onlinelibrary.wiley.com/doi/… Check out this paper by RIO researcher @TTipoe from @JohnFrater5 lab @NDMOxford. He reports how HIV-specific T cell responses in people with HIV are impacted by ATIs.

@TTipoe at #AIDS2024 presented on the impact of #ATIs on HIV-specific T cell responses.

#AIDS2024 @PennyZach1 and @jnim87 present their poster comparing #BNAB sensitivity prediction outcomes using blood or gut proviral DNA and rebound plasma RNA in people treated during primary HIV infection.

frontiersin.org/journals/imm… @PennyZach1 @JohnFrater5 @NDMOxford report that 29% of a UK cohort of people treated in PHI had predicted resistance to 10-1074 by single genome Env sequence prediction algorithm. This highlights the need for bNAb resistance screening in clinical trials.

Dr Amanda Clarke and Caroline Cable from @BSUHresearch share their experiences working on the #RIOtrial. @UHSussex is one of our 12 clinical sites participating in the study! To watch and find out more, visit riotrial.org 🌟💫

vimeo.com/886495898/2bb039f3… Watch Prof Sarah Fidler speak to Ms Louise Terry, a research nurse working on the #RIOtrial, to find out what's it like working on the study.

People living with HIV were surveyed on their views on joining studies like #RIOtrial which involving temporarily stopping ART (also known as ATIs). Read the paper by members of the RIO and HEATHER studies here! 🔽

🎙️vimeo.com/877037653/739f23f5… 🎙️ Johan, who is currently participating in the #RIOtrial, kindly agreed to share his experiences and feelings with Prof. Sarah Fidler about pausing antiretroviral therapy (ART) as part of the trial. Watch the #ParticipantInterview now ⬆️

Prof @SarahFidler7 gives an update on treatment interruption trials at #EACS2023

We're delighted to welcome the latest site offering the RIO study, based at the Churchill Hospital CCVTM in Oxford, bringing the total number of study sites to 12!

Missed #IAS2023? Dr @jnim87 and colleagues discuss #RIOtrial and other exciting updates from the cobference, available on the @STI_BMJ podcast now! 🔊 stibmj.podbean.com/e/ias23-c…

Hello from Brisbane! Dr @jnim87 from the #RIOtrial team will be presenting the "Clinical trials using bNAbs: the RIO study" at the #IAS2023 pre-conference meeting HIV cure and immunotherapy forum.

riotrial.org/news/2023/06/pr… Prof Sarah Fidler discussed long-term treatment options with a view to improving the quality of life for people living with HIV, and cure, in her podcast titled “Treatment to improve quality of life, long-acting options, and cure”.

We also welcome another clinic @StGeorgesTrust in South West London to the #RIOtrial! @drlisahamzah