Rakesh (@RK_Path) profile picture

Rakesh

@RK_Path

Oncopathologist, @MAHE_Manipal

Joined January 2019
  • Tweets2.5K
  • Following546
  • Followers281
1Media
Photo by Rakesh (@RK_Path)
Amoebic Colitis #pathology #GIpath
Image from Rakesh (@RK_Path)
Image from Rakesh (@RK_Path)
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#PathQuiz 🔬🧬 #GynPath A) Endometrioid Adenocarcinoma B) Mesonephric-like Adenocarcinoma C) Clear Cell Adenocarcinoma D) High-grade Serous Carcinoma #Pathology #GynPath
Pelvic mass in a 62-year-old female. Histology shows a complex tumor with eosinophilic colloid-like material in the lumens. Varied architectural patterns including tubules and angulated glands @IARCWHO

ALT Pelvic mass in a 62-year-old female. Histology shows a complex tumor with eosinophilic colloid-like material in the lumens. Varied architectural patterns including tubules and angulated glands @IARCWHO

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Splenic marginal zone lymphoma➡️look for these 2 zones: 🩸Central zone of small lymphocytes replacing reactive germinal centers 🩸Peripheral zone of small/medium-sized cells with abundant pale cytoplasm, resembling marginal zone cells #hemepath #lymsm #PathTwitter #MedTwitter
Image from Siba El Hussein, MD (@SibaElHussein)
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Do we have to grade medullary thyroid carcinomas? Yes. If there is tumor necrosis, ≥5 mitoses per 2 mm², or ≥5% Ki-67 labeling index, classify the tumor as high-grade MTC. What constitutes necrosis? See pic 2 Dr. Nishino - 2025 Diagnostic Pathology Update #USCAP #pathology #PathX #PathTwitter
Image from Janira Navarro (@Janiranavarro)
Image from Janira Navarro (@Janiranavarro)
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Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) Allows <1% true papillae True papillae: branching/arborizing structure lined by cells with nuclear atypia and containing fibrovascular cores (see pic 1) Not true papillae (see pic 2): - Transected follicle walls - Sanderson polster Dr. Nishino - 2025 Diagnostic Pathology Update #USCAP #pathology #PathX #PathTwitter
Image from Janira Navarro (@Janiranavarro)
Image from Janira Navarro (@Janiranavarro)
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Thyroid neoplasms - Helpful IHC table Dr. Nishino - 2025 Diagnostic Pathology Update #USCAP #pathology #PathX
Image from Janira Navarro (@Janiranavarro)
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#liverpath The #nutmeg liver Macroscopic demonstration of Budd–Chiari syndrome due to IVC leiomyosarcoma and a great teaching image for liver pathology
Image from Mukul Vij, MD 🇮🇳 (@vij_mukul)
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This is a MALE patient with a solitary nodule on CXR
Image from Runjan Chetty (@RunjanChetty)
Image from Runjan Chetty (@RunjanChetty)
Image from Runjan Chetty (@RunjanChetty)
Image from Runjan Chetty (@RunjanChetty)
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How do we use and interpret immunohistochemical stains in lymph node evaluations in hematopathology? Here is a summary table I prepared which I hope will be useful, especially for beginners! #PathEd #MedEd
Image from Pranav Patwardhan (@pranavp01)
Image from Pranav Patwardhan (@pranavp01)
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Organ and diagnosis? Colleague's case. Easier with a history, of course. #pathology #PathTwitter
Image from Mark Ong (@DrMarkOng)
Image from Mark Ong (@DrMarkOng)
Image from Mark Ong (@DrMarkOng)
Image from Mark Ong (@DrMarkOng)
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Another papillary thyroid carcinoma (PTC) subtype: Columnar cell PTC (0.2% of PTCs) is characterized by columnar cells with prominent nuclear pseudostratification. The pseudostratification and lack of abundant eosinophilic cytoplasm can help distinguish from the tall cell variant (see our last post). #EndoPath #ENTPath #HNPath
PAPILLARY CARCINOMA, COLUMNAR CELL SUBTYPE A: Hypercellular tumor with papillae lined by pseudostratified epithelium. B: The cells have a columnar appearance, high nuclear to cytoplasmic ratio, and pronounced nuclear pseudostratification.

ALT PAPILLARY CARCINOMA, COLUMNAR CELL SUBTYPE A: Hypercellular tumor with papillae lined by pseudostratified epithelium. B: The cells have a columnar appearance, high nuclear to cytoplasmic ratio, and pronounced nuclear pseudostratification.

PAPILLARY CARCINOMA, COLUMNAR CELL SUBTYPE, ENCAPSULATED A: This tumor was well defined and thinly encapsulated, separated from the adjacent parenchyma by a thin capsule. B: The tumor contains papillae lined by columnar cells with pseudostratified nuclei.

ALT PAPILLARY CARCINOMA, COLUMNAR CELL SUBTYPE, ENCAPSULATED A: This tumor was well defined and thinly encapsulated, separated from the adjacent parenchyma by a thin capsule. B: The tumor contains papillae lined by columnar cells with pseudostratified nuclei.

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Ovary-Endometrioid carcinoma Diverse morphologic features (pic 1) Endometrioid carcinoma with sex-cord pattern: Usually present presents with adenofibroma-like morphology Not infrequently they have and aberrant IHC pattern like PAX-8 negativity and CDX2 positivity Dr. Pilkington- Masters of Disguise: A Selection of Morphological Mimics in Gynae Tumour Pathology #ISGyP #Gynpath #pathology #PathX
Image from Janira Navarro (@Janiranavarro)
Image from Janira Navarro (@Janiranavarro)
Image from Janira Navarro (@Janiranavarro)
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Bone marrow from elderly adult with end-stage renal failure. Peri-trabecular fibrosis. Numerous osteoblasts, occasional osteoclasts. Dips in the bony trabeculae indicate bone resoprtion, but at the same time, abundant new bone formation (= woven rather than lamellar bone).
Image from Mark Ong (@DrMarkOng)
Image from Mark Ong (@DrMarkOng)
Image from Mark Ong (@DrMarkOng)
Image from Mark Ong (@DrMarkOng)
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This week, I learned not only that gangliocytic paragangliomas were reclassified by the WHO as composite gangliocytoma/neuroma and neuroendocrine tumor (CoGNET) - thank you Rhonda Yantiss - but also that they can express CD117/KIT to result in wrong diagnoses on small biopsies.
Image from Elizabeth Montgomery, MD (@LizMontgomeryMD)
Image from Elizabeth Montgomery, MD (@LizMontgomeryMD)
Image from Elizabeth Montgomery, MD (@LizMontgomeryMD)
Image from Elizabeth Montgomery, MD (@LizMontgomeryMD)
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FNA from a 75-year-old's 3.2 cm peripheral lung mass. What is your impression? A) Benign B) Malignant C) I need a higher power 🖼️ #CytoPath #PathTwitter #Pathology
Image from Charlie Herndon (@DrCycloPath)
Image from Charlie Herndon (@DrCycloPath)
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Reserve cells are immature epithelial cells residing underneath the columnar pulmonary cells as depicted in this sketch by @SaeedAsiry. Reserve cell hyperplasia can mimick small cell carcinoma (hyperchromatic nuclei with molding), but the cells are very small with no necrosis.
Image from Sam Khader, MD (@SamKhader)
Image from Sam Khader, MD (@SamKhader)
Image from Sam Khader, MD (@SamKhader)
Image from Sam Khader, MD (@SamKhader)
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This is a crazy case of bladder cytitis cystica et glandularis with extensive intestinal metaplasia and low-grade dysplasia. It resembles a colorectal adenoma! There is lots to learn in Dr. Alex Kryvenko's new book. Get yours at innovativesciencepress.com #UMiamiPath
Image from Innovative Science Press (@science_press)
Image from Innovative Science Press (@science_press)
Image from Innovative Science Press (@science_press)
Image from Innovative Science Press (@science_press)
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Unusual case - Colonic glomus tumor !
Image from Elizabeth Montgomery, MD (@LizMontgomeryMD)
Image from Elizabeth Montgomery, MD (@LizMontgomeryMD)
Image from Elizabeth Montgomery, MD (@LizMontgomeryMD)
Image from Elizabeth Montgomery, MD (@LizMontgomeryMD)
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50/F 5cm lung mass.Patient has an ontological history. #cytopath #pathtwitter #lung @pepeheffernan @vi_monappa @kriyer68 @DrGeeONE @kr_abhisek
Image from Anupama Arya (@AnupamaArya12)
Image from Anupama Arya (@AnupamaArya12)
Image from Anupama Arya (@AnupamaArya12)
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Fallopian tubes with nodular mesothelial/histiocytic hyperplasia - a benign, incidental finding Good to know about all these incidentalomas so you don't mistake them for something else (also to not waste resources on unnecessary IHC) #pathtwitter #gynpath #generalpath #pathoutpic
Image from Diane Brackett, MD (@dgbrackett)
Image from Diane Brackett, MD (@dgbrackett)
Image from Diane Brackett, MD (@dgbrackett)
Image from Diane Brackett, MD (@dgbrackett)
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Got a very interesting HER2 Immunohistochemistry to interpret today! What would you call it? #breastpath #breastcancer #her2 #pathX #PathTwitter #pathologists
Image from Jasmine Vickery (@VickeryJasmine)
Image from Jasmine Vickery (@VickeryJasmine)
Image from Jasmine Vickery (@VickeryJasmine)
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